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Internal Medicine

2022 ACR/EULAR classification criteria for granulomatosis with polyangiitis.

4 Feb, 2022 | 09:00h | UTC

2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Guideline: Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease.

4 Feb, 2022 | 08:49h | UTC

Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British Clinical Diabetologists and the Renal Association UK guideline update 2021 – BMC Nephrology

 

Clinical Practice Guideline for Optimal Hemodialysis Treatment.

4 Feb, 2022 | 08:47h | UTC

Executive Summary of the Korean Society of Nephrology 2021 Clinical Practice Guideline for Optimal Hemodialysis Treatment – Kidney Research and Clinical Practice

 

Anaphylaxis: Highlights from the practice parameter update.

4 Feb, 2022 | 08:43h | UTC

Anaphylaxis: Highlights from the practice parameter update – Cleveland Clinic Journal of Medicine

Original Article: Anaphylaxis—a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis – Journal of Allergy and Clinical Immunology

 

Review: Extraosseous calcification in kidney disease.

4 Feb, 2022 | 08:40h | UTC

Extraosseous calcification in kidney disease – Cleveland Clinic Journal of Medicine

 

Geriatric Choosing Wisely choice of recommendations in France: a pragmatic approach based on clinical audits.

4 Feb, 2022 | 08:46h | UTC

Geriatric Choosing Wisely choice of recommendations in France: a pragmatic approach based on clinical audits – BMC Geriatrics

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

Soft tissue sarcoma: Recognizing a rare disease.

4 Feb, 2022 | 08:41h | UTC

Soft tissue sarcoma: Recognizing a rare disease – Cleveland Clinic Journal of Medicine

 

Hyaluronic acid injections have increased for knee arthritis in the US, despite guideline recommendations against their use.

4 Feb, 2022 | 08:32h | UTC

Hyaluronic Acid Injections for Knee Osteoarthritis: Has Utilization Among Medicare Beneficiaries Changed Between 2012 and 2018? – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)

News Release: Hyaluronic acid injections have increased for knee arthritis – despite recommendations against their use

Related Guideline: Treatment of Osteoarthritis of the Knee: Evidence-Based Guideline, 2nd Edition – Journal of the American Academy of Orthopaedic Surgeons

 

Podcast: Infective Endocarditis Pearls.

4 Feb, 2022 | 08:27h | UTC

Infective Endocarditis Pearls – The Curbsiders

 

Study showed aminotransferase levels are often unremarkable in patients with alcohol-related cirrhosis and have a poor correlation with complications or death.

4 Feb, 2022 | 08:30h | UTC

Normal or Near Normal Aminotransferase Levels in Patients with Alcoholic Cirrhosis – American Journal of Medical Sciences (link to abstract – $ for full-text)

Commentary: Physicians over-relying on a commonly used laboratory test can miss liver cirrhosis – Medical University of South Carolina

 

An observational study including 15.670 people using methotrexate and 2.689 using leflunomide showed the incidences of discontinuation related to cytopenia, liver enzyme elevation, or kidney function decline.

4 Feb, 2022 | 08:21h | UTC

What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline? – Rheumatology

 

Psychosis in systemic lupus erythematosus (SLE): a 40-year experience of a specialist center showed most patients (66.7%) had full remission with a combination of antipsychotics and immunosuppressive therapy.

4 Feb, 2022 | 08:20h | UTC

Psychosis in systemic lupus erythematosus (SLE): 40-year experience of a specialist centre – Rheumatology

 

Thrombolytic use for STEMI: what ED clinicians should know.

4 Feb, 2022 | 08:23h | UTC

Thrombolytic Use for STEMI: What ED Clinicians Should Know – emDocs

 

Consensus Statement: Preoperative management of medications for psychiatric diseases.

3 Feb, 2022 | 09:59h | UTC

Preoperative Management of Medications for Psychiatric Diseases: Society for Perioperative Assessment and Quality Improvement Consensus Statement – Mayo Clinic Proceedings

 

Perspective: The origins, development, and context of the Lancet Commission on the Value of Death – “Death has turned from being a family, social, and cultural event to primarily a medical event”.

3 Feb, 2022 | 08:51h | UTC

The origins, development, and context of the Lancet Commission on the Value of Death – The BMJ

Related: The Lancet Commission: Experts warn of the increasing overmedicalization of death, call for radical rethink of how society cares for dying people.

 

Cluster randomized controlled trial: An innovative telemedical network to improve infectious disease management in critically ill patients and outpatients.

3 Feb, 2022 | 08:53h | UTC

An innovative telemedical network to improve infectious disease management in critically ill patients and outpatients: a stepped-wedge, cluster randomized controlled trial (TELnet@NRW) – Journal of Medical Internet Research

Related:

The “Choosing Wisely” initiative in infectious diseases – German Society of Infectious Diseases (link to abstract – $ for full-text)

Infectious Diseases Society of America: Five Things Physicians and Patients Should Question

 

A nationwide study in Sweden showed the risk of death doubled in patients with chronic disease and co-occurring psychiatric disorders.

3 Feb, 2022 | 08:49h | UTC

Risk of Death Doubled in Patients with Chronic Disease and Co-occurring Psychiatric Disorders – University of Oxford

Original Study: Psychiatric comorbidity and risk of premature mortality and suicide among those with chronic respiratory diseases, cardiovascular diseases, and diabetes in Sweden: A nationwide matched cohort study of over 1 million patients and their unaffected siblings – PLOS Medicine

 

Review: Behçet syndrome.

3 Feb, 2022 | 08:29h | UTC

Behçet syndrome – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Behçet syndrome (if the link is paywalled, try this one)

Related: EULAR recommendations for the management of Behçet’s syndrome

 

Outpatient Therapies for COVID-19: How do we choose?

2 Feb, 2022 | 08:53h | UTC

Outpatient Therapies for COVID-19: How do we choose? – Open Forum Infectious Diseases

 

A pragmatic RCT found low adherence and no additional benefit of prescribing a very low-protein diet in patients with advanced chronic kidney disease.

3 Feb, 2022 | 08:21h | UTC

No additional benefit of prescribing a very low-protein diet in patients with advanced Chronic Kidney Disease under regular nephrology care: a pragmatic, randomized, controlled trial – American Journal of Clinical Nutrition (link to abstract – $ for full-text)

 

Updated NIH COVID-19 Treatment Guidelines: Therapeutic management of nonhospitalized adults with COVID-19.

2 Feb, 2022 | 08:50h | UTC

Therapeutic Management of Nonhospitalized Adults With COVID-19 – NIH COVID-19 Treatment Guidelines

 

Commentary on Twitter

 

Perspective: Avoidance of β-blockers in patients who use stimulants is not supported by good evidence.

2 Feb, 2022 | 08:39h | UTC

Avoidance of β-blockers in patients who use stimulants is not supported by good evidence – Canadian Medical Association Journal

 

Perspective: The ongoing saga of normal saline vs. balanced fluids.

2 Feb, 2022 | 08:43h | UTC

The ongoing saga of normal saline versus balanced fluids – First10EM

Original studies:

RCT: In critically ill adults, using a balanced multielectrolyte solution did not lower the risk of death or acute kidney injury compared to standard saline.

Balanced Crystalloids versus Saline in Critically Ill Adults — A Systematic Review with Meta-Analysis – NEJM Evidence

Related:

BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.

BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.

Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline

 

Using melatonin for sleep is on the rise, study says, despite potential health harms.

2 Feb, 2022 | 08:41h | UTC

Using melatonin for sleep is on the rise, study says, despite potential health harms – CNN

Original Study: Trends in Use of Melatonin Supplements Among US Adults, 1999-2018 – JAMA (free for a limited period)

 

Cluster Randomized Trial: In older patients undergoing elective surgical procedures, a multimodal nonpharmacological prevention program reduced postoperative delirium occurrence and days with delirium.

2 Feb, 2022 | 08:38h | UTC

Outcomes of a Delirium Prevention Program in Older Persons After Elective Surgery: A Stepped-Wedge Cluster Randomized Clinical Trial – JAMA Surgery

Author Interview: Effective Delirium Prevention in Older Persons After Elective Surgery

 

Commentary on Twitter

 

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