Internal Medicine
Takotsubo Syndrome: A review of presentation, diagnosis and management.
2 Feb, 2022 | 08:25h | UTCRelated:
International Expert Consensus Document on Takotsubo Syndrome
International Registry: 16.6% of Patients with Takotsubo Syndrome Have Underlying Malignancy
Systematic Review: Long-Term Prognosis and Outcome Predictors in Takotsubo Syndrome
Cohort Study: Hospital Readmission Following Takotsubo Syndrome
DIC in Pregnancy: Pathophysiology, clinical characteristics, diagnostic scores, and treatments.
2 Feb, 2022 | 08:27h | UTC
M-A: Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis.
2 Feb, 2022 | 08:20h | UTCEfficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Review: Advance care planning and goals of care discussions in advanced liver disease.
2 Feb, 2022 | 08:17h | UTC
Review: Diagnosis and Management of Multiple Myeloma.
2 Feb, 2022 | 08:11h | UTCDiagnosis and Management of Multiple Myeloma: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis and Management of Multiple Myeloma – JAMA
Review: Eosinophils and eosinophilic immune dysfunction in health and disease.
2 Feb, 2022 | 08:15h | UTCEosinophils and eosinophilic immune dysfunction in health and disease – European Respiratory Review
Review: Prevention of atherosclerosis from childhood.
2 Feb, 2022 | 08:12h | UTCPrevention of atherosclerosis from childhood – Nature Reviews Cardiology (if the link is paywalled, try this one)
Observational study suggests Ceftaroline has comparable efficacy vs. Daptomycin for the treatment of Methicillin-Resistant Staphylococcus aureus bloodstream infection.
2 Feb, 2022 | 08:07h | UTC
Commentary on Twitter
New in OFID: A multicenter retrospective observational cohort study found no difference in treatment failure or mortality between MRSA bloodstream infections treated with ceftaroline or daptomycin.
📄: https://t.co/3QB5JXd8s5@PaulSaxMD @DrJLi @FungalDoc @IDpharmresearch pic.twitter.com/zNa9XRWP8F
— IDSA (@IDSAInfo) December 29, 2021
WHO Recommendations: Reducing the risk of cognitive decline and dementia.
1 Feb, 2022 | 09:50h | UTCReducing the Risk of Cognitive Decline and Dementia: WHO Recommendations – Frontiers in Neurology
Related:
New WHO toolkit promotes inclusion of people with dementia in society.
Dementia: number of people affected to triple in next 30 years – World Health Organization
The Lancet Commission: Experts warn of the increasing overmedicalization of death, call for radical rethink of how society cares for dying people.
1 Feb, 2022 | 09:55h | UTCHomepage: Lancet Commission on the Value of Death (free registration required for all articles)
Report of the Lancet Commission on the Value of Death: bringing death back into life
The precariousness of balancing life and death
Ros Taylor: seeing palliative care as relational
Commentary on Twitter (thread – click for more)
Increasing overmedicalisation at the end of life is denying people & their families a good death.
Towards a compassionate community model: The Lancet #ValueofDeath Commission calls for a radical rethink of care for the dying & attitudes to death. https://t.co/DpJiu1tOcV pic.twitter.com/FU9MgCO1J6
— The Lancet (@TheLancet) January 31, 2022
[Preprint] Study suggests SARS-CoV-2 Omicron subvariants BA.2 is even more transmissible than the original variant.
1 Feb, 2022 | 08:56h | UTCCommentaries:
Study suggests BA.2 COVID-19 subvariant more contagious – CIDRAP
‘Stealth Omicron’ spreads more than original strain: study – MedicalXpress
Commentary from the author on Twitter (thread – click for more)
New Preprint Out!
“Transmission of SARS-CoV-2 Omicron VOC subvariants BA.1 and BA.2: Evidence from Danish Households”
We investigate the secondary attack rate (SAR) in #Omicron BA.1 vs. BA.2 households in Demark, 20 December 2021 – 18 January 2022.https://t.co/F3XBH2LnW9
1/ pic.twitter.com/MwGPNYkOg8— Frederik Plesner Lyngse (@LyngseF) January 31, 2022
Consensus: Nephrotoxins and acute kidney injury.
1 Feb, 2022 | 08:46h | UTC
M-A: Vasopressin and glucocorticoids for in-hospital cardiac arrest.
1 Feb, 2022 | 08:43h | UTC
Commentary on Twitter
Systemic review and meta analysis post VAM-IHCA.
▶️ Moderate certainty for benefit with steroids and vasopressin on ROSC
▶️ Less certainty for longer term outcomes @mathiasholmb@LarsWAndersen1 @AsgerGranfeldthttps://t.co/K3jZ1gBs1h— Critical Care Reviews (@CritCareReviews) January 4, 2022
Recommendations on the everyday management of patients with spondyloarthritis, including psoriatic arthritis.
1 Feb, 2022 | 08:44h | UTC
RCT: In patients with rheumatoid arthritis, treatment with oral drug Tofacitinib increases cardiovascular and cancer risk compared to treatment with subcutaneous TNF inhibitors.
1 Feb, 2022 | 08:35h | UTCCardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis – New England Journal of Medicine (link to abstract – $ for full-text)
Video: CV and Cancer Risk with Tofacitinib in RA – New England Journal of Medicine
Commentary: CV, Cancer Risk Up With Tofacitinib for Rheumatoid Arthritis – HealthDay
RCT: A comprehensive geriatric assessment hospital at home may be a cost-effective alternative to hospital admission.
1 Feb, 2022 | 08:32h | UTC
Review | Hepatic encephalopathy: thinking beyond ammonia.
1 Feb, 2022 | 08:36h | UTCHepatic Encephalopathy: Thinking Beyond Ammonia – Clinical Liver Disease
Review: Primary care-based cardiovascular disease risk management after adverse pregnancy outcomes.
1 Feb, 2022 | 08:29h | UTCPrimary Care–Based Cardiovascular Disease Risk Management After Adverse Pregnancy Outcomes: a Narrative Review – Journal of General Internal Medicine (if the link is paywalled, try this one)
See also: thread from the author on Twitter summarizing the article
Related:
AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk
Cohort Study: Preeclampsia and Cardiovascular Disease
Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors (recent studies on the subject)
M-A: The diagnostic accuracy of syndromic management for genital ulcer disease.
1 Feb, 2022 | 08:12h | UTC
Systematic Review: Self‐management interventions for people with chronic obstructive pulmonary disease.
1 Feb, 2022 | 08:21h | UTCSummary: Self-management for people with chronic obstructive pulmonary disease – Cochrane Library
Commentary on Twitter
Graphical abstract for our new #Cochrane Review on #Self-management interventions for people with #COPD thanks to @jade_schrijver for drafting it and the epic review update https://t.co/4V7d9TUHMh pic.twitter.com/tgL67df9rg
— CochraneAirways (@CochraneAirways) January 17, 2022
Registry study in Denmark found an increased bleeding risk with the association of systemic Fluconazole and Apixaban (OR 3.5; 95% CI, 1.4-10.6).
1 Feb, 2022 | 08:13h | UTC
Review: Multidisciplinary management of tracheobronchial injury.
1 Feb, 2022 | 08:17h | UTCMultidisciplinary management of tracheobronchial injury – European Respiratory Review
Position Paper: Preventing heart failure.
30 Jan, 2022 | 14:53h | UTC
FDA halts use of antibody drugs that don’t work vs. Omicron.
30 Jan, 2022 | 14:35h | UTCFDA halts use of antibody drugs that don’t work vs. omicron – Associated Press
RCT: Vitamin D supplementation for older adults (mean age 67 years) for 5 years reduced the risk of autoimmune diseases by 22%. Absolute risk in the treatment group was 0.95% vs. 1.19% in the placebo group.
30 Jan, 2022 | 14:30h | UTCCommentary: Vitamin D and fish oil supplements may help prevent autoimmune disease, study says – CNN
Related:
USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases