Gastrointestinal Surgery (all articles)
Global variation in postoperative mortality and complications after cancer surgery: a multicenter, prospective cohort study in 82 countries
25 Jan, 2021 | 01:21h | UTCCommentary: Better post-surgical care would boost cancer survival chances – University of Birmingham
Commentary on Twitter (thread – Click for more)
https://twitter.com/ewenharrison/status/1352401851711418372
Meta-analysis: Does near-infrared fluorescent cholangiography with indocyanine green reduce bile duct injuries and conversions to open surgery during laparoscopic or robotic cholecystectomy?
25 Jan, 2021 | 01:06h | UTCDoes near-infrared fluorescent cholangiography with indocyanine green reduce bile duct injuries and conversions to open surgery during laparoscopic or robotic cholecystectomy? — A meta-analysis – Surgery (link to abstract – $ for full-text)
Cohort study: Tomographic radiation in patients who underwent appendectomy linked to increased risk of hematologic malignant neoplasms
22 Jan, 2021 | 08:25h | UTCRisk of Hematologic Malignant Neoplasms From Abdominopelvic Computed Tomographic Radiation in Patients Who Underwent Appendectomy – JAMA Surgery (free for a limited period)
Commentary: Optimizing the Gold Standard—Low-Dose Computed Tomography Modalities as a Part of Clinical Practice in Acute Appendicitis Imaging – JAMA Surgery (free for a limited period)
Author Interview: Risk of Hematologic Malignant Neoplasms From Abdominopelvic CT Radiation
Role of imaging in visceral vascular emergencies
20 Jan, 2021 | 01:14h | UTCRole of imaging in visceral vascular emergencies – Insights into Imaging
Study: Similar length of hospital stay with laparoscopic vs. open gastrectomy for gastric cancer
20 Jan, 2021 | 01:05h | UTCLength of Hospital Stay With Laparoscopic vs Open Gastrectomy for Gastric Cancer – The ASCO Post
Postsurgical disease recurrence in stage I to III colorectal cancer may be predicted by ctDNA
20 Jan, 2021 | 01:07h | UTCCommentaries: Postsurgical Disease Recurrence in Stage I to III Colorectal Cancer May Be Predicted by ctDNA – The ASCO Post AND Liquid Biopsy Predicts Colon Cancer Relapse Months Before CT – MedPage Today (free registration required)
Randomized trial: Prevention of biliary fistula after partial hepatectomy by transcystic biliary drainage
19 Jan, 2021 | 01:19h | UTCPrevention of biliary fistula after partial hepatectomy by transcystic biliary drainage: randomized clinical trial – British Journal of Surgery (link to abstract – $ for full-text)
Randomized trial: Pneumatic dilation does not work for persistent dysphagia after antireflux surgery
19 Jan, 2021 | 01:13h | UTCPneumatic dilation for persistent dysphagia after antireflux surgery, a multicentre single-blind randomised sham-controlled clinical trial – Gut (link to abstract – $ for full-text)
Systematic review: The association of Alvimopan treatment with postoperative outcomes after abdominal surgery
19 Jan, 2021 | 01:05h | UTCThe association of alvimopan treatment with postoperative outcomes after abdominal surgery: A systematic review across different surgical procedures and contexts of perioperative care – Surgery (link to abstract – $ for full-text)
Meta-analysis of observational studies: Proton pump inhibitors linked to increased risk for recurrent Clostridioides difficile infection
17 Jan, 2021 | 22:00h | UTC
Postdischarge virtual visits for low-risk surgeries: A randomized noninferiority clinical trial
17 Jan, 2021 | 21:57h | UTCPostdischarge Virtual Visits for Low-risk Surgeries: A Randomized Noninferiority Clinical Trial – JAMA Surgery (free for a limited period)
Commentary: Surgical Centers Warm Up to Video Chats, Texts for Patient Follow-Up – MedPage Today (free registration required)
Randomized trial: Biological mesh results in significantly more complications compared to synthetic mesh in noncomplex ventral hernia repair
15 Jan, 2021 | 08:17h | UTCSynthetic Versus Biological Mesh in Laparoscopic and Open Ventral Hernia Repair (LAPSIS): Results of a Multinational, Randomized, Controlled, and Double-blind Trial – Annals of Surgery (link to abstract – $ for full-text)
Commentary on Twitter
The use of biological mesh resulted in significantly more complications (P = 0.013),also after adjusting for hernia type, body mass index,and study site.The trial was prematurely stopped due to unacceptable high recurrence rate in the biological mesh arms https://t.co/P0fV50xopv
— George Ferzli (@drferzli) December 25, 2020
Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin
14 Jan, 2021 | 01:57h | UTCEditorial: Evolving Issues in the Use of Antibiotics for the Treatment of Uncomplicated Appendicitis
Commentary: More Support for Single-Drug Antibiotics for Uncomplicated Appendicitis – Physician’s Weekly
Commentary on Twitter
In this RCT comparing 7d oral moxifloxacin vs 2d IV ertapenam 5d oral levofloxacin metronidazole for adults w uncomplicated #appendicitis, Tx success was >65% for both, but oral #antibiotics did not meet noninferiority criteria vs IV PO https://t.co/SwcopsGZTm #VisualAbstract
— JAMA (@JAMA_current) January 12, 2021
Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations
14 Jan, 2021 | 01:36h | UTCMeta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations – Surgery (link to abstract – $ for full-text)
Randomized trial: Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) improve outcomes vs. traditional approach in locally advanced rectal cancer
12 Jan, 2021 | 01:12h | UTCShort-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
New online: phase 3 RAPIDO trial: Short-course #radiotherapy followed by #chemotherapy before total mesorectal excision (TME) vs standard of care in locally advanced #rectalcancer https://t.co/bTgUC6Lo39 #crcsm pic.twitter.com/Iu3HbQ1xjG
— The Lancet Oncology (@TheLancetOncol) December 8, 2020
[Abstract Only] Meta-Analysis: Not enough evidence to recommend the use of a prosthetic Mesh for prevention of parastomal hernia
12 Jan, 2021 | 01:18h | UTCMeta-Analysis and Systematic Review of the Use of a Prosthetic Mesh for Prevention of Parastomal Hernia – Annals of Surgery (link to abstract – $ for full-text)
Meta-analysis: Total neoadjuvant therapy vs. standard therapy in locally advanced rectal cancer
12 Jan, 2021 | 01:10h | UTCCommentaries: Personalizing Treatment for Rectal Cancer: Total Neoadjuvant Therapy Is Leading the Way AND Total Neoadjuvant Therapy Improves Rectal Cancer Pathologic Response – Physician’s Weekly
Related meta-analysis (just published): Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials – Cancers
Commentary on Twitter
Systematic review & meta-analysis finds total neoadjuvant therapy for locally adv. rectal cancer is associated with a doubling of pathologic complete response vs standard chemoradiation plus by adjuvant chemo. @anup_kasi @KUMedCenter @geriradonc @agrothey https://t.co/oRccCh5bEb
— JAMA Network Open (@JAMANetworkOpen) December 16, 2020
Study suggests the intensity of active surveillance in patients with rectal cancer managed by a watch-and-wait approach could be reduced if they maintain a complete clinical response within the first 3 years
12 Jan, 2021 | 01:11h | UTCCommentaries: Rectal cancer patients who “watch and wait” may only need few years of stringent follow-up – eCancer AND Intense rectal cancer surveillance may be reduced – MDedge
Randomized trial: Laparoscopic lavage vs. primary resection for perforated purulent diverticulitis; similar long-term results, but recurrence was more common after laparoscopic lavage
10 Jan, 2021 | 20:25h | UTCLaparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: Long-term Outcomes From the Scandinavian Diverticulitis (SCANDIV) Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)
Commentary: Laparoscopic Lavage a Safe Option in Perforated Diverticulitis — No difference versus resection in long-term severe complications, but recurrence more common – MedPage Today (free registration required)
Randomized trial: In surgical patients at moderate or high risk of venous thromboembolism, pharmaco-thromboprophylaxis alone is as good as the combination of pharmaco-thromboprophylaxis and graduated compression stockings
16 Dec, 2020 | 10:00h | UTC
Randomized trial: Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer does not benefit patients vs. surgery alone
16 Dec, 2020 | 09:55h | UTCExtensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
ICYMI – Results of the EXPEL trial show no survival benefit with extensive peritoneal #lavage after surgery vs surgery alone; not recommended for patients undergoing curative #gastrectomy for #gastriccancer.https://t.co/rCgHNt7VZ1#gitwitter #some4surgery pic.twitter.com/BC1BJgElYm
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) December 9, 2020
Randomized trial: Among patients with advanced rectal cancer, short-course radiotherapy followed by chemotherapy before total mesorectal excision reduces disease-related treatment failure compared to standard treatment
15 Dec, 2020 | 01:29h | UTC
Commentary on Twitter
New online: phase 3 RAPIDO trial: Short-course #radiotherapy followed by #chemotherapy before total mesorectal excision (TME) vs standard of care in locally advanced #rectalcancer https://t.co/bTgUC6Lo39 #crcsm pic.twitter.com/Iu3HbQ1xjG
— The Lancet Oncology (@TheLancetOncol) December 8, 2020
Randomized trial: No difference in quality of life and slightly greater weight loss with Roux-en-Y Gastric Bypass compared to Laparoscopic Sleeve Gastrectomy at 7 years
11 Dec, 2020 | 09:20h | UTCEffect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss and Quality of Life at 7 Years in Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentary: Using Quality-of-Life Measures to Determine the Ideal Bariatric Procedure – JAMA Surgery (free for a limited period)
Systematic Review: Probiotics probably make little or no difference for patients with acute infectious diarrhea
10 Dec, 2020 | 08:53h | UTCProbiotics for treating acute infectious diarrhoea – Cochrane Library
Summary: Do probiotics help to treat acute infectious diarrhoea? – Cochrane Library
Randomized trial: In patients with recurrent, complicated, or persistent painful diverticulitis, sigmoid resection improved quality of life but was associated with a small but significant risk of major complications
10 Dec, 2020 | 08:51h | UTCAuthor Interview: Laparoscopic Sigmoid Resection vs Conservative Treatment in Improving Quality of Life in Diverticulitis
Commentary on Twitter
https://twitter.com/drferzli/status/1330948905941557248


