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Gastrointestinal Surgery (all articles)

RCT: Primary tumor resection plus chemotherapy vs. chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases

7 Mar, 2021 | 19:23h | UTC

Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial – Journal of Clinical Oncology

Original study: No Survival Benefit to Primary Resection Before Chemo in Metastatic Colorectal Cancer – Medscape / Reuters

 

 


RCT: Biologic mesh implantation is associated with serious abdominal wall complications in patients undergoing emergency abdominal surgery

7 Mar, 2021 | 19:07h | UTC

Biologic mesh implantation is associated with serious abdominal wall complications in patients undergoing emergency abdominal surgery: A randomized-controlled clinical trial – Trauma & Acute Care Surgery (link to abstract – $ for full-text)

 


RCT: Safety of combined division vs. separate division of the splenic vein in patients undergoing distal pancreatectomy

5 Mar, 2021 | 08:25h | UTC

Safety of Combined Division vs Separate Division of the Splenic Vein in Patients Undergoing Distal Pancreatectomy: A Noninferiority Randomized Clinical Trial – JAMA Surgery

Commentaries: An Evidence-Based Beneficial Shortcut for Distal Pancreatic Resection – JAMA Surgery AND Surgical Shortcut Noninferior to Standard Technique for Pancreatic Resection – Physician’s Weekly

 

Commentary on Twitter

https://twitter.com/JAMASurgery/status/1367157880261144577

 


ACG Clinical Guidelines: Start colorectal cancer screening at 45

5 Mar, 2021 | 08:31h | UTC

ACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology

Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45

 


RCT: Mixed findings with Terlipressin plus Albumin for the treatment of Type 1 hepatorenal syndrome

4 Mar, 2021 | 08:35h | UTC

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

 


RCT: Albumin provides no benefit to hospitalized patients with decompensated cirrhosis

4 Mar, 2021 | 08:37h | UTC

A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Albumin provides no benefit to hospitalized patients with advanced liver disease – University College London

 


RCT: Irrigating acetic acid solution during colonoscopy for the detection of sessile serrated neoplasia

4 Mar, 2021 | 08:16h | UTC

Irrigating Acetic Acid Solution During Colonoscopy for the Detection of Sessile Serrated Neoplasia: A Randomized Controlled Trial – Digestive Diseases and Sciences

 


RCT: Laparoscopic anterior resection with or without transanal tube for rectal cancer patients

4 Mar, 2021 | 08:02h | UTC

Laparoscopic anterior resection with or without transanal tube for rectal cancer patients – A multicenter randomized controlled trial – The American Journal of Surgery (link to abstract – $ for full-text)

 


M-A: Glue vs. mechanical mesh fixation in laparoscopic inguinal hernia repair

2 Mar, 2021 | 01:29h | UTC

Glue versus mechanical mesh fixation in laparoscopic inguinal hernia repair: meta-analysis and trial sequential analysis of randomized clinical trials – British Journal of Surgery

 


Laparoscopic Roux-en-Y gastric bypass vs. laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials

2 Mar, 2021 | 01:27h | UTC

Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials (SLEEVEPASS and SM-BOSS) – British Journal of Surgery

Visual abstract: Merged SLEEVEPASS and SM-BOSS trials

 


Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis

26 Feb, 2021 | 08:17h | UTC

Drains, Germs, or Steel: Multidisciplinary Management of Acute Colonic Diverticulitis – Digestive Diseases and Sciences

 


Study: Unhealthy alcohol use common after bariatric surgery

26 Feb, 2021 | 08:14h | UTC

Association of Bariatric Surgical Procedures With Changes in Unhealthy Alcohol Use Among US Veterans – JAMA Network Open

Commentaries: Unhealthy Alcohol Use—A Common Iatrogenic Complication of Bariatric Surgery – JAMA Network Open AND Bariatric Surgery May Increase Risk of Unhealthy Alcohol Use – Psychiatric News Alert AND Bariatric Surgery Ups Risk of Alcohol Abuse – Physician’s Weekly

 

Commentary on Twitter

 


RCT: Hypothermic machine perfusion in liver transplantation

25 Feb, 2021 | 08:44h | UTC

Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Cold Perfusion Cuts Liver Transplant Complications – MedPage Today

 


Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers

24 Feb, 2021 | 02:00h | UTC

Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers – News Medical

Original study: Gastroesophageal reflux disease: A risk factor for laryngeal squamous cell carcinoma and esophageal squamous cell carcinoma in the NIH‐AARP Diet and Health Study cohort – Cancer

 


Review: Diagnosis and treatment of metastatic colorectal cancer

19 Feb, 2021 | 02:07h | UTC

Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review – JAMA (free for a limited period)

 


M-A: Role of diet in colorectal cancer incidence

17 Feb, 2021 | 01:12h | UTC

Role of Diet in Colorectal Cancer Incidence: Umbrella Review of Meta-analyses of Prospective Observational Studies – JAMA Network Open

 


RCT: Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer

16 Feb, 2021 | 01:44h | UTC

Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer (RELARC): a randomised, controlled, phase 3, superiority trial – The Lancet Oncology (link to abstract – $ for full-text)

 


RCT: In patients with cirrhosis treated with TIPS, prophylactic rifaximin reduced the risk for Hepatic Encephalopathy

7 Feb, 2021 | 21:10h | UTC

The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Rifaximin prevents overt hepatic encephalopathy after TIPS – HealthDay

 

Commentary on Twitter

 


Duration of adjuvant doublet chemotherapy (3 or 6 months) in patients with high-risk stage II colorectal cancer

3 Feb, 2021 | 01:10h | UTC

Duration of Adjuvant Doublet Chemotherapy (3 or 6 months) in Patients With High-Risk Stage II Colorectal Cancer – Journal of Clinical Oncology

Commentary: Adjuvant Doublet Chemotherapy for High-Risk Stage II Colorectal Cancer: 3- or 6- Month Duration? – The ASCO Post

 


Meta-analysis: Risk of colorectal cancer and cancer related mortality after detection of low-risk or high-risk adenomas, compared with no adenoma, at index colonoscopy

3 Feb, 2021 | 01:20h | UTC

Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review And Meta-Analysis – Gastroenterology (link to abstract – $ for full-text)

Related studies: Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies – Gastroenterology AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text) AND Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA

Related guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology

 


Pancreatic Cysts—An Overview and Summary of Society Guidelines, 2021

28 Jan, 2021 | 01:19h | UTC

Pancreatic Cysts—An Overview and Summary of Society Guidelines, 2021 – JAMA (free for a limited period)

 


Acute Pancreatitis: A Review

28 Jan, 2021 | 01:20h | UTC

Acute Pancreatitis: A Review – JAMA (free for a limited period)

Podcast: Acute Pancreatitis Part 1 of 2: Diagnosis

Podcast: Acute Pancreatitis Part 2 of 2: Treatment

 


10-year follow up of a randomized trial shows metabolic surgery is more effective than conventional medical therapy for the control of type 2 diabetes

26 Jan, 2021 | 00:44h | UTC

Metabolic surgery versus conventional medical therapy in patients with type 2 diabetes: 10-year follow-up of an open-label, single-centre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Gastrointestinal surgery can be a ‘cure’ for type 2 diabetes finds new long-term study – King’s College London

 


Cohort study: Aspirin linked to reduced risk of colon cancer if you start it before age 70

26 Jan, 2021 | 00:37h | UTC

Aspirin Use and Risk of Colorectal Cancer Among Older Adults – JAMA Oncology (free for a limited period)

Commentaries: Does aspirin lower colorectal cancer risk in older adults? It depends on when they start – Massachusetts General Hospital AND Aspirin Use Cuts CRC Risk in Those Initiating Use Before Age 70 – Physician’s Weekly

 


Randomized trial: In patients with colorectal peritoneal metastases, adding hyperthermic intraperitoneal chemotherapy to cytoreductive surgery does not improve survival and causes more frequent late complications

26 Jan, 2021 | 00:34h | UTC

Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

https://twitter.com/TheLancetOncol/status/1351469448264351752

 


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