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Gastrointestinal Surgery (all articles)

Systematic review: The association of Alvimopan treatment with postoperative outcomes after abdominal surgery

19 Jan, 2021 | 01:05h | UTC

The association of alvimopan treatment with postoperative outcomes after abdominal surgery: A systematic review across different surgical procedures and contexts of perioperative care – Surgery (link to abstract – $ for full-text)

Meta-analysis of observational studies: Proton pump inhibitors linked to increased risk for recurrent Clostridioides difficile infection

17 Jan, 2021 | 22:00h | UTC

Proton pump inhibitor use and risk for recurrent Clostridioides difficile infection: A systematic review & meta-analysis – Clinical Microbiology and Infection

 

Postdischarge virtual visits for low-risk surgeries: A randomized noninferiority clinical trial

17 Jan, 2021 | 21:57h | UTC

Postdischarge Virtual Visits for Low-risk Surgeries: A Randomized Noninferiority Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Surgical Centers Warm Up to Video Chats, Texts for Patient Follow-Up – MedPage Today (free registration required)

 

Randomized trial: Biological mesh results in significantly more complications compared to synthetic mesh in noncomplex ventral hernia repair

15 Jan, 2021 | 08:17h | UTC

Synthetic Versus Biological Mesh in Laparoscopic and Open Ventral Hernia Repair (LAPSIS): Results of a Multinational, Randomized, Controlled, and Double-blind Trial – Annals of Surgery (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

14 Jan, 2021 | 01:57h | UTC

Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial – JAMA

Editorial: Evolving Issues in the Use of Antibiotics for the Treatment of Uncomplicated Appendicitis

Commentary: More Support for Single-Drug Antibiotics for Uncomplicated Appendicitis – Physician’s Weekly

 

Commentary on Twitter

 

Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations

14 Jan, 2021 | 01:36h | UTC

Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations – Surgery (link to abstract – $ for full-text)

 

Randomized trial: Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) improve outcomes vs. traditional approach in locally advanced rectal cancer

12 Jan, 2021 | 01:12h | UTC

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

[Abstract Only] Meta-Analysis: Not enough evidence to recommend the use of a prosthetic Mesh for prevention of parastomal hernia

12 Jan, 2021 | 01:18h | UTC

Meta-Analysis and Systematic Review of the Use of a Prosthetic Mesh for Prevention of Parastomal Hernia – Annals of Surgery (link to abstract – $ for full-text)

 

Meta-analysis: Total neoadjuvant therapy vs. standard therapy in locally advanced rectal cancer

12 Jan, 2021 | 01:10h | UTC

Total Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-analysis – JAMA Network Open

Commentaries: Personalizing Treatment for Rectal Cancer: Total Neoadjuvant Therapy Is Leading the Way AND Total Neoadjuvant Therapy Improves Rectal Cancer Pathologic Response – Physician’s Weekly

Related meta-analysis (just published): Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials – Cancers

 

Commentary on Twitter

 

Study suggests the intensity of active surveillance in patients with rectal cancer managed by a watch-and-wait approach could be reduced if they maintain a complete clinical response within the first 3 years

12 Jan, 2021 | 01:11h | UTC

Conditional recurrence-free survival of clinical complete responders managed by watch and wait after neoadjuvant chemoradiotherapy for rectal cancer in the International Watch & Wait Database: a retrospective, international, multicentre registry study – The Lancet Oncology

Commentaries: Rectal cancer patients who “watch and wait” may only need few years of stringent follow-up – eCancer AND Intense rectal cancer surveillance may be reduced – MDedge

 

Randomized trial: Laparoscopic lavage vs. primary resection for perforated purulent diverticulitis; similar long-term results, but recurrence was more common after laparoscopic lavage

10 Jan, 2021 | 20:25h | UTC

Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: Long-term Outcomes From the Scandinavian Diverticulitis (SCANDIV) Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Laparoscopic Lavage a Safe Option in Perforated Diverticulitis — No difference versus resection in long-term severe complications, but recurrence more common – MedPage Today (free registration required)

 

Randomized trial: In surgical patients at moderate or high risk of venous thromboembolism, pharmaco-thromboprophylaxis alone is as good as the combination of pharmaco-thromboprophylaxis and graduated compression stockings

16 Dec, 2020 | 10:00h | UTC

Compression stockings in addition to low-molecular-weight heparin to prevent venous thromboembolism in surgical inpatients requiring pharmacoprophylaxis: the GAPS non-inferiority RC – Health Technology Assessment

 

Randomized trial: Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer does not benefit patients vs. surgery alone

16 Dec, 2020 | 09:55h | UTC

Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Peritoneal Lavage in Cancer Gastrectomy Is Not a Wash— Study found no survival benefit and more adverse events and deaths compared with standard surgery – MedPage Today

 

Commentary on Twitter

 

Randomized trial: Among patients with advanced rectal cancer, short-course radiotherapy followed by chemotherapy before total mesorectal excision reduces disease-related treatment failure compared to standard treatment

15 Dec, 2020 | 01:29h | UTC

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology

 

Commentary on Twitter

 

Randomized trial: No difference in quality of life and slightly greater weight loss with Roux-en-Y Gastric Bypass compared to Laparoscopic Sleeve Gastrectomy at 7 years

11 Dec, 2020 | 09:20h | UTC

Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss and Quality of Life at 7 Years in Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Using Quality-of-Life Measures to Determine the Ideal Bariatric Procedure – JAMA Surgery (free for a limited period)

 

Systematic Review: Probiotics probably make little or no difference for patients with acute infectious diarrhea

10 Dec, 2020 | 08:53h | UTC

Probiotics for treating acute infectious diarrhoea – Cochrane Library

Summary: Do probiotics help to treat acute infectious diarrhoea? – Cochrane Library

 

Randomized trial: In patients with recurrent, complicated, or persistent painful diverticulitis, sigmoid resection improved quality of life but was associated with a small but significant risk of major complications

10 Dec, 2020 | 08:51h | UTC

Comparing Laparoscopic Elective Sigmoid Resection With Conservative Treatment in Improving Quality of Life of Patients With Diverticulitis: The Laparoscopic Elective Sigmoid Resection Following Diverticulitis (LASER) Randomized Clinical Trial – JAMA Surgery

Author Interview: Laparoscopic Sigmoid Resection vs Conservative Treatment in Improving Quality of Life in Diverticulitis

Commentary: Laparoscopic sigmoid resection for recurrent diverticulitis associated with higher quality of life scores – 2 Minute Medicine

 

Commentary on Twitter

 

Review: Perioperative venous thromboembolism prophylaxis

3 Dec, 2020 | 08:28h | UTC

Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings

 

State of the art review: Advances in the diagnosis and management of gastroesophageal reflux disease

30 Nov, 2020 | 00:52h | UTC

Advances in the diagnosis and management of gastroesophageal reflux disease – The BMJ (free for a limited period)

 

Randomized trial: Colorectal cancer screening with repeated fecal immunochemical tests detects more colorectal cancer and advanced adenomas compared to screening sigmoidoscopy

25 Nov, 2020 | 09:05h | UTC

Colorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial – Gastroenterology (link to abstract – $ for full-text)

 

Safe surgery: A cluster randomized trial showed that the implementation of control charts with feedback on indicators to surgical teams was associated with concomitant reductions in major adverse events in patients

9 Nov, 2020 | 01:23h | UTC

Effect of monitoring surgical outcomes using control charts to reduce major adverse events in patients: cluster randomised trial – The BMJ

 

Guideline synopsis for follow-up colonoscopy after polypectomy. Repeat Col in 7 to 10 y after 1 to 2 tubular adenomas (TA) < 10 mm; Repeat Col in 3 to 5 y after 3 to 4 TA < 10 mm; Repeat Col in 3 y after 5 to 10 TA < 10 mm; Repeat Col in 3 years after 1 or more TA > 10 mm

9 Nov, 2020 | 01:17h | UTC

Recommendations for Follow-up Colonoscopy After Polypectomy – JAMA (free for a limited period)

Author interview: New Recommendations for How Often to Repeat Colonoscopy Following Polypectomy

Original guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology

 

Randomized trial: Similar outcomes with goal-directed hemodynamic therapy vs. restrictive normovolemic therapy in major open abdominal surgery

6 Nov, 2020 | 09:34h | UTC

Goal-directed hemodynamic therapy versus restrictive normovolemic therapy in major open abdominal surgery: A randomized controlled trial – Surgery

 

Commentary on Twitter

 

Review: Management of common postoperative complications

4 Nov, 2020 | 09:26h | UTC

Management of Common Postoperative Complications – Mayo Clinic Proceedings

 

USPSTF draft statement now recommends starting colorectal cancer screening at 45

28 Oct, 2020 | 08:57h | UTC

Draft Recommendation Statement: Colorectal Cancer Screening – U.S. Preventive Services Task Force

Commentaries: Colorectal cancer screening should start five years earlier — at 45 — expert panel says – STAT AND USPSTF Lowers Colorectal Cancer Screening Age to 45 in Draft Recommendation – NEJM Journal Watch

 

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