Randomized trial: Biological mesh results in significantly more complications compared to synthetic mesh in noncomplex ventral hernia repair

Synthetic Versus Biological Mesh in Laparoscopic and Open Ventral Hernia Repair (LAPSIS): Results of a Multinational, Randomized, Controlled, and Double-blind Trial – Annals of Surgery (link to abstract – $ for full-text)

Commentary on Twitter

The use of biological mesh resulted in significantly more complications (P = 0.013),also after adjusting for hernia type, body mass index,and study site.The trial was prematurely stopped due to unacceptable high recurrence rate in the biological mesh arms https://t.co/P0fV50xopv

— George Ferzli (@drferzli) December 25, 2020