Meta-analysis: Total neoadjuvant therapy vs. standard therapy in locally advanced rectal cancer

Total Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-analysis – JAMA Network Open

Commentaries: Personalizing Treatment for Rectal Cancer: Total Neoadjuvant Therapy Is Leading the Way AND Total Neoadjuvant Therapy Improves Rectal Cancer Pathologic Response – Physician’s Weekly

Related meta-analysis (just published): Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials – Cancers

Commentary on Twitter

Systematic review & meta-analysis finds total neoadjuvant therapy for locally adv. rectal cancer is associated with a doubling of pathologic complete response vs standard chemoradiation plus by adjuvant chemo. @anup_kasi @KUMedCenter @geriradonc @agrothey https://t.co/oRccCh5bEb

— JAMA Network Open (@JAMANetworkOpen) December 16, 2020