Family Medicine
Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19.
29 Mar, 2022 | 10:05h | UTC
Cumulative burden of psychiatric disorders and self-harm across 26 adult cancers.
29 Mar, 2022 | 09:58h | UTCCumulative burden of psychiatric disorders and self-harm across 26 adult cancers – Nature Medicine
See also: Suicide risk and mortality among patients with cancer – Nature Medicine (if the link is paywalled, try this one)
Invited Commentary: Shining a light on the psychological burden of cancer – Nature Medicine
Commentary on Twitter
Patients with cancer who are diagnosed with a psychiatric disorder had a higher incidence of mortality and are at greater risk of self-harm compared with other patients with cancer, according to a paper published in @NatureMedicine. https://t.co/U5b7ODKSNd pic.twitter.com/816N6ZCfms
— Nature Portfolio (@NaturePortfolio) March 28, 2022
Multidisciplinary consensus for the management of pulmonary thromboembolism.
29 Mar, 2022 | 09:54h | UTC
Scientists find that the impact of social media on wellbeing varies across adolescence.
29 Mar, 2022 | 09:56h | UTCNews Release: Scientists find that the impact of social media on wellbeing varies across adolescence – University of Cambridge
Original Study: Windows of developmental sensitivity to social media – Nature Communications
Commentaries:
Teenage social media use linked to less life-satisfaction for some – BBC
Social media may affect girls’ mental health earlier than boys’, study finds – The Guardian
Expert reaction to study on social media use and wellbeing over adolescence – Science Media Centre
Guideline: Treatment of unspecific back pain in children and adolescents.
29 Mar, 2022 | 09:52h | UTC
Association of antipsychotic drug exposure in pregnancy with risk of neurodevelopmental disorders: a national birth cohort study.
29 Mar, 2022 | 08:46h | UTCAssociation of Antipsychotic Drug Exposure in Pregnancy With Risk of Neurodevelopmental Disorders: A National Birth Cohort Study – JAMA Internal Medicine (free for a limited period)
Crossover RCT: Effects of experimental sleep restriction on energy intake, energy expenditure, and visceral obesity.
29 Mar, 2022 | 08:31h | UTCEffects of Experimental Sleep Restriction on Energy Intake, Energy Expenditure, and Visceral Obesity – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Lack of sleep increases unhealthy abdominal fat, study finds – Mayo Clinic
Related: RCT: Advising overweight patients to increase sleep duration may reduce caloric intake.
Review: Short and oral antimicrobial therapy for diabetic foot infection.
29 Mar, 2022 | 08:29h | UTC
AGA clinical practice update on the role of diet in irritable bowel syndrome.
28 Mar, 2022 | 10:04h | UTCRelated:
10 mistakes in dietary management of irritable bowel syndrome and how to avoid them.
Supplement: Irritable bowel syndrome and related conditions.
RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome
Guidelines for the treatment of irritable bowel syndrome
ACG Clinical Guideline: Management of irritable bowel syndrome
M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome
Study challenges the theory that light alcohol consumption benefits heart health.
28 Mar, 2022 | 10:09h | UTCNews Release: Large study challenges the theory that light alcohol consumption benefits heart health – Massachusetts General Hospital
Original Study: Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease – JAMA Network Open
Related: No amount of alcohol is good for the heart, says World Heart Federation.
Commentary on Twitter
Cohort study found confounding factors mediate the J-shaped association between alcohol intake & CVD. Genetic epidemiology suggests any amount of alcohol is associated with increased CVD risk, with exponential risk increases at heavier consumption levels. https://t.co/PrPDmyt87q
— JAMA Network Open (@JAMANetworkOpen) March 25, 2022
The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.
28 Mar, 2022 | 09:48h | UTCM-A: Most patients with allergy to Penicillin can be given Cefazolin
Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy
Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule
Consensus Recommendations: Management of a Surgical Patient with a Label of Penicillin Allergy
Practical Guide for Pharmacists to Successfully Implement Penicillin Allergy Skin Testing
NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk
Commentary on Twitter
In this cohort study of more than 330,000 children, less than 5% were labeled with penicillin allergy with wide variation across practices, with 8% of those labeled despite not receiving any penicillin prescription. https://t.co/kvXcm1RKRd
— JAMA Network Open (@JAMANetworkOpen) March 15, 2022
Retrospective Cohort: A population-based study in Sweden and Norway did not find an increased risk of pregnancy complications after COVID-19 vaccination.
28 Mar, 2022 | 09:51h | UTCAssociation of SARS-CoV-2 Vaccination During Pregnancy With Pregnancy Outcomes – JAMA
See also: Association of COVID-19 Vaccination in Pregnancy With Adverse Peripartum Outcomes – JAMA
Editorial: COVID-19 mRNA Vaccines During Pregnancy: New Evidence to Help Address Vaccine Hesitancy – JAMA
News Release: No increase in pregnancy complications after COVID-19 vaccination – Karolinska Institutet
Half of all women experience false positive mammograms after 10 years of annual screening.
28 Mar, 2022 | 08:53h | UTC
Commentary on Twitter
Comparative effectiveness study finds biennial screening interval, older age, and non-dense breasts were associated with larger reductions in false-positive results than screening with tomosynthesis vs digital mammography. @BCSC_research @dmiglio https://t.co/16CMFH5bcI
— JAMA Network Open (@JAMANetworkOpen) March 25, 2022
Study Commentary: Symptoms can appear up to 10 years before a Parkinson’s disease diagnosis in a primary care setting.
28 Mar, 2022 | 08:37h | UTCOriginal Study: Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population – JAMA Neurology (link to abstract – $ for full-text)
A practical guide to implementing SMART in asthma management.
28 Mar, 2022 | 08:42h | UTC
M-A: Comparative effectiveness of statins on non-HDL cholesterol in people with diabetes and at risk of cardiovascular disease.
25 Mar, 2022 | 10:01h | UTCNews Release: Best statins for reducing cardiovascular risk in people with diabetes found – University of Manchester
Commentary on Twitter
This network meta-analysis indicated that rosuvastatin, at moderate and high intensity doses, and simvastatin and atorvastatin, at high intensity doses, were most effective at moderately reducing levels of non-HDL-C in patients with diabeteshttps://t.co/NwUf4sX5KA
— The BMJ (@bmj_latest) March 24, 2022
Review: How to improve compliance to hypertension treatment.
28 Mar, 2022 | 08:31h | UTCHow to improve compliance to hypertension treatment – European Society of Cardiology
Commentary on Twitter
#NonAdherence is a major factor for suboptimal #BP control. A one-size-fits-all approach is not ideal. A personalised approach is needed to address it. @spoorthy_burli in #CVPracticeJournal https://t.co/mm1Tjd8fPT@HeartOTXHeartMD @iamritu @AnastasiaSMihai @KreutzReinhold pic.twitter.com/Gdd693gfmU
— European Society of Cardiology Journals (@ESC_Journals) March 25, 2022
Cochrane Special Collection: Diagnosing tuberculosis.
25 Mar, 2022 | 09:57h | UTCDiagnosing tuberculosis – Cochrane Library
3 orthopedic surgeries that might be doing patients (and their pockets) more harm than good.
25 Mar, 2022 | 09:54h | UTC
Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study.
25 Mar, 2022 | 09:56h | UTCCommentaries:
Sweeteners may be linked to increased cancer risk – new research – The Conversation
Expert reaction to observational study of sweeteners and cancer risk – Science Media Centre
Review: Tobacco and nicotine use.
25 Mar, 2022 | 08:49h | UTCTobacco and nicotine use – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Infographic: Tobacco and nicotine use (if the link is paywalled, try this one)
Commentary on Twitter
https://twitter.com/DiseasePrimers/status/1507089870950318118
[Preprint] RCT: Vitamin D supplements did not prevent Covid-19 or other acute respiratory infections.
25 Mar, 2022 | 09:49h | UTCRelated:
RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19
Commentary on Twitter (thread – click for more)
https://twitter.com/KarlPfleger/status/1506871284214337543
RCT: In patients with chronic migraine and overuse of symptomatic medications, migraine preventive therapy without switching or limiting the frequency of the overused medication was non-inferior to switching to a different symptomatic medication with a maximum limit of two treatment days/week.
25 Mar, 2022 | 08:44h | UTCPatient-Centered Treatment of Chronic Migraine With Medication Overuse: A Prospective, Randomized, Pragmatic Clinical Trial – Neurology (link to abstract – $ for full-text)
Study Commentary: Widespread screening catches more cases of depression. But follow-up care still falls far short.
25 Mar, 2022 | 08:34h | UTC
Cohort Study: Risk of mental health problems in children and youths following concussion.
25 Mar, 2022 | 08:29h | UTCRisk of Mental Health Problems in Children and Youths Following Concussion – JAMA Network Open
Commentaries:
Concussion Linked to Mental Health Issues Among Children Aged 5 to 18 Years – HealthDay