Family Medicine | Page 54 of 374 | Links Medicus Content Curation & Alerts in Medicine

ACC/AHA blood pressure categories – A systematic review of the relationship with adverse pregnancy outcomes.

21 Oct, 2022 | 13:05h | UTC

American College of Cardiology/American Heart Association blood pressure categories – a systematic review of the relationship with adverse pregnancy outcomes – American Journal of Obstetrics & Gynecology (PDF)

Commentary on Twitter

American College of Cardiology/American Heart Association blood pressure categories – a systematic review of the relationship with adverse pregnancy outcomes https://t.co/8YbeVAysXS @acog @RCObsGyn @MySMFM @ranzcog pic.twitter.com/DiOKsihXWW

— AJOG (@AJOG_thegray) October 12, 2022

AGA clinical practice guideline on pharmacological interventions for adults with obesity.

21 Oct, 2022 | 13:06h | UTC

AGA Clinical Practice Guideline on Pharmacological Interventions for Adults With Obesity – Gastroenterology

News Release: First medical guideline recommends new prescription medications for weight loss, ranks the most effective drugs – American Gastroenterological Association

RCT | Effect of financial voucher incentives on the cessation of smoking in pregnant women.

21 Oct, 2022 | 12:58h | UTC

Effect of financial voucher incentives provided with UK stop smoking services on the cessation of smoking in pregnant women (CPIT III): pragmatic, multicentre, single blinded, phase 3, randomised controlled trial – The BMJ

Editorial: Financial incentives for sustained smoking abstinence in pregnancy – The BMJ

News Release: Shopping vouchers help women to stop smoking during pregnancy – BMJ Newsroom

Commentary on Twitter (thread – click for more)

Appreciate there are other things going on but …
Results from our phase III trial of financial incentives for smoking cessation in pregnancy published today in @bmj_latest 🧵1/3https://t.co/1El3JFSOQu

— Linda Bauld (@LindaBauld) October 20, 2022

RCT | A telemedicine model for abortion in South Africa.

21 Oct, 2022 | 12:51h | UTC

A telemedicine model for abortion in South Africa: a randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

News Release: Telemedicine can give vulnerable women access to safe medical abortions – Karolinska Institutet

Commentaries on Twitter

Researchers report that their telemedicine model for medical #abortion—with uterine palpation as the sole in-person component—was non-inferior to standard care in a low-resource setting. https://t.co/kUMVxYBrI9 pic.twitter.com/sPjgxsB1bK

— The Lancet (@TheLancet) August 30, 2022

Medical #abortion can be carried out safely and effectively via #telemedicine, finds an RCT published in @TheLancet by Margit Endler and colleagues at KI & @UCT_news. This method can potentially reduce the number of unsafe abortions in resource-poor areas. https://t.co/UoNPnD23Hp pic.twitter.com/ac0mvyaJeU

— Karolinska Institutet (@karolinskainst) September 7, 2022

Note: medical abortion is not a legalized procedure in Brazil.

RCT | Evaluation of mRNA-1273 vaccine in children 6 months to 5 years of age.

20 Oct, 2022 | 12:35h | UTC

Evaluation of mRNA-1273 Vaccine in Children 6 Months to 5 Years of Age – New England Journal of Medicine

Commentary on Twitter

Randomized, placebo-controlled trial of the 2-dose @moderna_tx vaccine in children 6 months to 5 years, during Omicron. Safe in ~4,800 kids; good immune response; efficacy vs infections 👇https://t.co/DkLXAQQaeZ @NEJM pic.twitter.com/ettWOnDGQf

— Eric Topol (@EricTopol) October 19, 2022

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

20 Oct, 2022 | 12:34h | UTC

Myocarditis after BNT162b2 Vaccination in Israeli Adolescents – New England Journal of Medicine

Commentary on Twitter

Among Israeli adolescents between 12 and 15 years of age who received the BNT162b2 vaccine, 9 cases of mild myocarditis were observed, mainly after the second dose. https://t.co/OatYqN4IPD pic.twitter.com/c96d1o7wnt

— NEJM (@NEJM) October 19, 2022

Cohort Study | Associations of hypertriglyceridemia onset age with cardiovascular disease and all‐cause mortality in adults.

20 Oct, 2022 | 12:25h | UTC

Associations of Hypertriglyceridemia Onset Age With Cardiovascular Disease and All‐Cause Mortality in Adults: A Cohort Study – Journal of the American Heart Association

Pooled analysis of cohort studies | Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters.

19 Oct, 2022 | 14:28h | UTC

Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales – The Lancet

Commentaries:

Prioritisation of COVID-19 boosters in the omicron era – The Lancet

COVID booster halved severe illness, but some groups still at higher risk – CIDRAP

Case-control study | Odds of hospitalization for COVID-19 after 3 vs. 2 doses of mRNA vaccine by time since booster dose.

19 Oct, 2022 | 14:27h | UTC

Odds of Hospitalization for COVID-19 After 3 vs 2 Doses of mRNA COVID-19 Vaccine by Time Since Booster Dose – JAMA

News Release: Study indicates COVID-19 boosters among vaccinated individuals significantly reduce hospitalization rates – Providence Health & Services

Systematic Review | Antihistamines to prevent and treat motion sickness.

19 Oct, 2022 | 14:21h | UTC

Antihistamines for motion sickness – Cochrane Library

Summary: Antihistamines to prevent and treat motion sickness – Cochrane Library

Commentary on Twitter

New from Cochrane Evidence: Antihistamines are likely to reduce the risk of developing motion sickness in susceptible adults under normal conditions, e.g. traveling by car or boat, but they may be more likely to cause drowsiness than placebo https://t.co/l3gtX9ad7T… pic.twitter.com/EcQZYmwMrU

— Cochrane ENT (@CochraneENT) October 17, 2022

RCT | Combination of pitavastatin and ezetimibe vs. monotherapy of pitavastatin in patients with primary hypercholesterolemia.

19 Oct, 2022 | 14:15h | UTC

A Multicenter, Randomized, Double-Blind, Active-Controlled, Factorial Design, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of Pitavastatin and Ezetimibe Versus Monotherapy of Pitavastatin in Patients With Primary Hypercholesterolemia – Clinical Therapeutics

M-A | Cardiovascular and renal efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients without diabetes.

19 Oct, 2022 | 14:11h | UTC

Cardiovascular and renal efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients without diabetes: a systematic review and meta-analysis of randomised placebo-controlled trials – BMJ Open

Retrospective Cohort Study | Trends in the association between diabetes and cardiovascular events, 1994-2019.

18 Oct, 2022 | 12:58h | UTC

Trends in the Association Between Diabetes and Cardiovascular Events, 1994-2019 – JAMA (free for a limited period)

RCT | Two-year effects of Semaglutide in adults with overweight or obesity.

18 Oct, 2022 | 12:53h | UTC

Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial – Nature Medicine

Commentary: STEP 5: Sustained semaglutide treatment maintains weight loss – medwire News

RCT: Effect of continued weekly subcutaneous Semaglutide vs. placebo on weight loss maintenance in adults with overweight or obesity

RCT: High dose once a week Semaglutide (2.4 mg) in adults with overweight or obesity, and type 2 diabetes

RCT: Effect of high-dose subcutaneous Semaglutide vs. placebo in adults with overweight or obesity

RCT: Once-weekly, high-dose semaglutide is effective for improving overweight or obesity among non-diabetic adults

Commentary on Twitter

Results from the STEP 5, testing #semaglutide as an adjuct to behavioral interventions in adults with #overweight or #obesity, demonstrate sustained #weightloss over a period of 104 weeks. @ProfBatterhamMD @seanwharton @DrGeorgiaRigas https://t.co/0mBtzhCYID

— Nature Medicine (@NatureMedicine) October 11, 2022

Perspective | The polypill: from concept and evidence to implementation.

18 Oct, 2022 | 12:55h | UTC

The polypill: from concept and evidence to implementation – The Lancet (free registration required)

News Release: The polypill could avoid millions of premature deaths, heart attacks and strokes every year, say leading cardiology experts – McMaster University

#ESCCongress | In patients within 6 months of a myocardial infarction, a polypill containing aspirin, ramipril, and atorvastatin resulted in a lower risk of major adverse cardiovascular events compared to usual care.

#ESCCongress – M-A: Polypills with and without aspirin substantially reduce cardiovascular disease, myocardial infarction, stroke, revascularization, and cardiovascular death in primary cardiovascular disease prevention.

Opinion: A new important study supports wider use of the polypill

#AHA20 – Randomized trial: A polypill comprising statins, multiple blood pressure lowering drugs, and aspirin prevents cardiovascular events among patients at intermediate cardiovascular risk

Perspective: Are Polypills and Population-based Treatment the Next Big Things?

The Polypill Revisited: Why We Still Need Population-Based Approaches in the Precision Medicine Era

Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population

Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases

Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart

Perspective: The Polypill and the Long Journey to Major Impact

Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care

Guideline | Sarcopenia: screening, diagnosis, management and prevention.

18 Oct, 2022 | 12:51h | UTC

Singapore Clinical Practice Guidelines For Sarcopenia: Screening, Diagnosis, Management and Prevention – The Journal of Frailty & Aging

Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management – The journal of nutrition, health & aging

Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report – Age and Ageing

Cohort Study | Association of attention-deficit/hyperactivity disorder diagnosis with adolescent quality of life.

18 Oct, 2022 | 12:48h | UTC

Association of Attention-Deficit/Hyperactivity Disorder Diagnosis With Adolescent Quality of Life – JAMA Network Open

Commentary on Twitter

Adolescents with an ADHD diagnosis reported similar quality of life overall and on 3 subdomains but worse outcomes for 5 other aspects of quality of life compared adolescents with similar levels of hyperactive/inattentive behaviors but no ADHD diagnosis. https://t.co/5o0MNfEzjD

— JAMA Network Open (@JAMANetworkOpen) October 13, 2022

Cohort Study | Association of daily step count and intensity with incident dementia.

18 Oct, 2022 | 12:38h | UTC

Association of Daily Step Count and Intensity With Incident Dementia in 78 430 Adults Living in the UK – JAMA Neurology

Commentaries:

Walking Daily Linked to Lower Dementia Risk, but How Many Steps Does It Take? – Psychiatric News Alert

Higher Step Counts Equal Better CV Health: UK Biobank – TCTMD

Cohort Study | Association of step counts over time with the risk of chronic diseases.

Cohort Study | Prospective associations of daily step counts and intensity with cancer and cardiovascular disease incidence and mortality and all-cause mortality.

Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts.

M-A | Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome.

18 Oct, 2022 | 12:37h | UTC

Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials – Therapeutic Advances in Endocrinology and Metabolism

Post-trial follow-up | Longer-term all-cause and cardiovascular mortality with intensive blood pressure control.

17 Oct, 2022 | 12:41h | UTC

Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control: A Secondary Analysis of a Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

Author Interview: Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control – JAMA

Commentaries:

Benefits of Intensive Blood Pressure Control May Not Persist After Trial Intervention – HCP Live

Study Highlights Importance of Long-term Management of Hypertension – Wake Forest University School of Medicine

SPRINT Trial final report: targeting a systolic BP of less than 120 mm Hg in patients at increased CV risk is associated with improved CV and mortality outcomes but increases the risk of serious adverse events.

Study: Real-world blood pressure measurements vs. measurements taken in the SPRINT trial

Studies: Intensive versus Standard Blood-Pressure Control

Commentary on Twitter

In a secondary analysis of SPRINT, the mortality benefits of intensive BP control attenuated after the trial, while outpatient systolic BP increased by an average of 7 mm Hg for participants in the intensive treatment group. https://t.co/INSo2zYzhp #Research

— JAMA Cardiology (@JAMACardio) October 12, 2022

A practical approach to the guideline-directed pharmacological treatment of heart failure with reduced ejection fraction.

17 Oct, 2022 | 12:15h | UTC

A practical approach to the guideline-directed pharmacological treatment of heart failure with reduced ejection fraction – ESC Heart Failure

Review | Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease.

14 Oct, 2022 | 14:19h | UTC

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy – European Heart Journal – Cardiovascular Pharmacotherapy

Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology

Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology

Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis – Health Technology Assessment

Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports

How-to guide for medication reviews in older adults with cancer: A Young International Society of Geriatric Oncology and Nursing & Allied Health Interest Group initiative – Journal of Geriatric Oncology

Deprescribing in Palliative Cancer Care – Life

Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360

Process evaluation of implementation strategies to reduce potentially inappropriate medication prescribing in older population: A scoping review – Research in Social and Administrative Pharmacy

AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review – Gastroenterology

Development of a Metric to Detect and Decrease Low-Value Prescribing in Older Adults – JAMA Network Open

The MedSafer Study—Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial – JAMA Internal Medicine

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines – Supportive Care in Cancer

Prescribing practices, patterns, and potential harms in patients receiving palliative care: A systematic scoping review – Exploratory Research in Clinical and Social Pharmacy

A narrative review of evidence to guide deprescribing among older adults – Journal of General and Family Medicine

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens – The Lancet Health Longevity

Polypharmacy Management in Older Patients – Mayo Clinic Proceedings

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt international

Eliminating Medication Overload: A National Action Plan – Lown Institute

International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action – Drugs & Aging

Common ED Medication Errors: Polypharmacy – emDocs

Current and future perspectives on the management of polypharmacy – BMC Family Practice

Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety

Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international

Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety

Special Statement | Postpartum visit checklists for normal pregnancy and complicated pregnancy.

14 Oct, 2022 | 14:18h | UTC

Society for Maternal-Fetal Medicine Special Statement: Postpartum visit checklists for normal pregnancy and complicated pregnancy – American Journal of Obstetrics & Gynecology

Original Guideline: ACOG Postpartum Toolkit (PDF)

Position Statement | Home blood pressure monitoring.

14 Oct, 2022 | 14:16h | UTC

Home blood pressure monitoring: a position statement from the Korean Society of Hypertension Home Blood Pressure Forum – Clinical Hypertension

2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement – Journal of Hypertension

Current applications and limitations of European guidelines on blood pressure measurement: implications for clinical practice – Internal and Emergency Medicine

Randomized Diagnostic Study: home blood pressure measurements correlate better with 24-h ambulatory monitoring measurements compared to clinic, and kiosk measurements.

Study suggests a 30-second interval between automated office blood pressure measurements is as accurate and reliable as a 60-second interval.

USPSTF Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement – diagnostic confirmation with blood pressure measurements outside of the clinical setting is advised before starting treatment

Study suggests that 7 days of home blood pressure monitoring is likely better than 24h ambulatory monitoring or 3 office measurements

RCT | A low-intensity psychosocial intervention improved recovery from depression in older adults in Brazil.

14 Oct, 2022 | 14:09h | UTC

A task-shared, collaborative care psychosocial intervention for improving depressive symptomatology among older adults in a socioeconomically deprived area of Brazil (PROACTIVE): a pragmatic, two-arm, parallel-group, cluster-randomised controlled trial – The Lancet Health Longevity

Invited Commentary: Empowering older adults and their communities to cope with depression in resource-limited settings – The Lancet Health Longevity

Commentary on Twitter

Empowering older adults and their communities to cope with #depression in resource-limited settings https://t.co/8GShpxpcOX @clausuemoto #Geriatrics

Our commentary @LancetLongevity about the incredible PRO-ACTIVE intervention by @scazufca & cols https://t.co/x2UerUFAYY pic.twitter.com/IP0DqTmGdP

— Marlon Aliberti (@marlon_aliberti) October 3, 2022

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