Family Medicine | Page 55 of 374 | Links Medicus Content Curation & Alerts in Medicine

RCT | Allopurinol does not improve outcomes in patients with ischemic heart disease without previous gout.

13 Oct, 2022 | 13:53h | UTC

Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial – The Lancet

Invited Commentary: Xanthine oxidase inhibition for cardiovascular disease prevention – The Lancet

Commentary on Twitter

Despite favorable effects on surrogate endpoints in smaller trials, in an RCT trial of 5,721 pts with CAD, allopurinol did not significantly improve cardiovascular prognosis compared to placebo https://t.co/ITW4HAwI2K @TheLancet pic.twitter.com/EggHM8flle

— Pradeep Natarajan (@pnatarajanmd) October 7, 2022

Under a Creative Commons Attribution (CC BY 4.0) License

Incidence of myocarditis/pericarditis following mRNA COVID-19 vaccination among children and younger adults in the US.

13 Oct, 2022 | 13:51h | UTC

Incidence of Myocarditis/Pericarditis Following mRNA COVID-19 Vaccination Among Children and Younger Adults in the United States – Annals of Internal Medicine

News Release: Incidence of myocarditis/pericarditis following mRNA COVID-19 vaccination among children, younger adults in the US – American College of Physicians

Commentary on Twitter (thread – click for more)

Let me me perfectly clear about the evidence for myocarditis after mRNA vaccines
1. There is a notable increased incidence, age 12-39, males, with each dose (Table)https://t.co/XXQbyeLiSP pic.twitter.com/wLTZT3fppy

— Eric Topol (@EricTopol) October 12, 2022

Commentary on Twitter

Let me me perfectly clear about the evidence for myocarditis after mRNA vaccines
1. There is a notable increased incidence, age 12-39, males, with each dose (Table)https://t.co/XXQbyeLiSP pic.twitter.com/wLTZT3fppy

— Eric Topol (@EricTopol) October 12, 2022

Review | Transient ischemic attack and minor stroke: diagnosis, risk stratification and management.

13 Oct, 2022 | 13:50h | UTC

Transient ischemic attack and minor stroke: diagnosis, risk stratification and management – Canadian Medical Association Journal

15-year benefits of sigmoidoscopy screening on colorectal cancer incidence and mortality: a pooled analysis of randomized trials.

13 Oct, 2022 | 13:48h | UTC

15-Year Benefits of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality: A Pooled Analysis of Randomized Trials – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: One sigmoidoscopy significantly reduces long-term CRC incidence in both men and women – American College of Physicians

RCT | Effect of colonoscopy screening on risks of colorectal cancer and related death.

RCT: One-time flexible sigmoidoscopy screening is associated with long-term reduction in colorectal cancer incidence and mortality.

ACP Guideline: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults

BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy

Current and future colorectal cancer screening strategies – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one in PMC)

Consensus Statement: U.S. Multi-Society Task Force on Colorectal Cancer now suggests average-risk CRC screening begins at age 45.

USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.

ACG Clinical Guidelines: Start colorectal cancer screening at 45

Commentary on Twitter

A pooled analysis evaluating 15-yr effect of sigmoidoscopies found that receiving 1 #sigmoidoscopy significantly reduces long-term incidence of CRC in men and women: https://t.co/QXj5VRMHeo pic.twitter.com/s82sOJmBzr

— Annals of Int Med (@AnnalsofIM) October 11, 2022

Cohort Study | New and progressive medical conditions after pediatric sepsis hospitalization requiring critical care.

13 Oct, 2022 | 13:45h | UTC

New and Progressive Medical Conditions After Pediatric Sepsis Hospitalization Requiring Critical Care – JAMA Pediatrics (free for a limited period)

Commentary on Twitter

The development or progression of comorbid conditions occurred in over 10% of children who survived #sepsis hospitalization, suggesting that they may benefit from structured follow-up to identify and address new or worsening medical conditions. https://t.co/yfAt60PsU6

— JAMA Pediatrics (@JAMAPediatrics) October 11, 2022

Cohort Study | Duration of diabetes and use of insulin are the most important predictors of diabetic retinopathy.

13 Oct, 2022 | 13:44h | UTC

Presence and development of diabetic retinopathy in 153 238 patients with type 2 diabetes in the Danish Registry of Diabetic Retinopathy – Acta Ophthalmologica

Commentary: Insulin Use May Predict the Development of Diabetic Retinopathy – HCP Live

Cohort Study | Association of step counts over time with the risk of chronic diseases.

13 Oct, 2022 | 13:36h | UTC

Association of step counts over time with the risk of chronic disease in the All of Us Research Program – Nature Medicine

News Release: Counting Steps Can Reduce Disease Risk: Study – Vanderbilt University Medical Center

Cohort Study | Prospective associations of daily step counts and intensity with cancer and cardiovascular disease incidence and mortality and all-cause mortality.

Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts.

Commentary on Twitter

Using a wearable activity tracker to count and increase the number and intensity of steps taken daily can reduce the risk of several common chronic diseases, according to a study published in @NatureMedicine. https://t.co/bhoof63fBH pic.twitter.com/pA651wDWJs

— Nature Portfolio (@NaturePortfolio) October 12, 2022

RCT | No difference in cardiovascular outcomes with evening vs. morning dosing of usual antihypertensives.

12 Oct, 2022 | 14:01h | UTC

Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial – The Lancet

USPSTF Statement | Screening for anxiety is recommended in children and adolescents aged 8 to 18 years.

12 Oct, 2022 | 13:58h | UTC

Screening for Anxiety in Children and Adolescents: US Preventive Services Task Force Recommendation Statement – JAMA

Editorial: Screening for Pediatric Anxiety Disorders – JAMA

Evidence Report: Screening for Anxiety in Children and Adolescents: Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

JAMA Patient Page: Screening for Anxiety in Children and Adolescents

Author interview: USPSTF Recommendations: Screening for Anxiety in Children and Adolescents, and Depression and Suicide Risk Screening in Children and Adolescents – JAMA

USPSTF Statement | Screening for depression and suicide risk is recommended in children and adolescents aged 12 to 18 years.

12 Oct, 2022 | 14:00h | UTC

Screening for Depression and Suicide Risk in Children and Adolescents: US Preventive Services Task Force Recommendation Statement – JAMA

Editorial: Screening for Adolescent Depression and Suicide Risk – JAMA

Evidence Report: Screening for Depression and Suicide Risk in Children and Adolescents: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

JAMA Patient Page: Screening for Depression and Suicide Risk in Children and Adolescents

Author Interview: USPSTF Recommendations: Screening for Anxiety in Children and Adolescents, and Depression and Suicide Risk Screening in Children and Adolescents – JAMA

Guideline | Evaluation and management of venous thromboembolism.

12 Oct, 2022 | 13:55h | UTC

Joint Guideline on Venous Thromboembolism – 2022 – Arquivos Brasileiros de Cardiologia

Benefits and risks associated with continuation of anti–TNF after 24 weeks of pregnancy in inflammatory bowel disease.

12 Oct, 2022 | 13:52h | UTC

Benefits and Risks Associated With Continuation of Anti–Tumor Necrosis Factor After 24 Weeks of Pregnancy in Women With Inflammatory Bowel Disease – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Anti-TNF continuation after 24 weeks of pregnancy beneficial to persons with IBD, does not affect neonatal outcomes – American College of Physicians

Commentary: Continuation of Anti-TNF for IBD After 24 Weeks of Pregnancy Beneficial – HealthDay

Commentary on Twitter

10 year trial found continuation of #AntiTNF treatment after 24 weeks of pregnancy appears beneficial for #IBD activity and prematurity, not affecting neonatal outcomes and serious infections in the offspring. @EPIPHARE https://t.co/YuytSQqDsE pic.twitter.com/CRGN80K93A

— Annals of Int Med (@AnnalsofIM) September 27, 2022

RCT | Effect of colonoscopy screening on risks of colorectal cancer and related death.

11 Oct, 2022 | 13:42h | UTC

Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

In gold-standard trial, invitation to colonoscopy reduced cancer incidence but not death – STAT

New study examines the effectiveness of colonoscopies – CNN

Estimated global proportions of persistent fatigue, cognitive, and respiratory symptoms following symptomatic COVID-19.

11 Oct, 2022 | 13:39h | UTC

Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021 – JAMA

Commentaries:

Women And Hospitalized Patients More Prone To Long Covid, Study Finds – Forbes

Nearly two-thirds of long COVID patients are female, global study finds – UPI

Commentary on Twitter

A new @IHME_UW modeling study on #LongCovid based upon 1.2 million people with Covid from 22 countrieshttps://t.co/evMcFVJ2vU @JAMA_current pic.twitter.com/qt1bgHkaVV

— Eric Topol (@EricTopol) October 10, 2022

Perspective | Hydrochlorothiazide vs. chlorthalidone – what is the difference?

11 Oct, 2022 | 13:40h | UTC

Hydrochlorothiazide Versus Chlorthalidone–What is the Difference? – Circulation (free for a limited period)

Meta-analysis: Chlorthalidone vs. hydrochlorothiazide

Large Observational Study Suggests Hydrochlorothiazide may be as Effective as Chlortalidone with Less Adverse Effects

Commentary on Twitter

There are big differences among diuretics even within the same class. So let us rethink the class effect. https://t.co/ruE4IYeFf2. Here I discuss what we know about HCTZ vs CTD. pic.twitter.com/cyljdi04v9

— Rajiv Agarwal MD, MS (@AgarwalRajivMD) October 8, 2022

Consensus document for the detection and management of chronic kidney disease.

11 Oct, 2022 | 13:38h | UTC

Information and consensus document for the detection and management of chronic kidney disease – Nefrología

Guideline Summary | Diagnostic stewardship for urinary tract infection.

11 Oct, 2022 | 13:37h | UTC

Diagnostic stewardship for urinary tract infection: A snapshot of the expert guidance – Cleveland Clinic Journal of Medicine

Original Guideline: Optimal Urine Culture Diagnostic Stewardship Practice—Results from an Expert Modified-Delphi Procedure – Clinical Infectious Diseases

Development of a symptom-based tool for screening of children at high risk of preschool asthma.

11 Oct, 2022 | 13:34h | UTC

Development of a Symptom-Based Tool for Screening of Children at High Risk of Preschool Asthma – JAMA Network Open

News Release: Simple new tool allows primary caregivers to detect young kids at high risk of asthma – McMaster University

Commentary on Twitter

The CHILDhood Asthma Risk Tool #CHART applied at 3 years of age outperforms mAPI and physician diagnosis for screening children a high-risk of #PersistentWheeze by age 5. #OAResearch https://t.co/mBFGV4djlz

— JAMA Network Open (@JAMANetworkOpen) October 6, 2022