RCT | No difference in cardiovascular outcomes with evening vs. morning dosing of usual antihypertensives.

Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial – The Lancet

Related: [News release – not published yet] #ESCCongres – RCT | Evening dosing of blood pressure medication not better than morning dosing.

Related Consensus Statement: Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension – Journal of Hypertension

Related study (conflicting results): Bedtime Hypertension Treatment Improves Cardiovascular Risk Reduction in Randomized Trial