Perspective | Hydrochlorothiazide vs. chlorthalidone – what is the difference?

Hydrochlorothiazide Versus Chlorthalidone–What is the Difference? – Circulation (free for a limited period)

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Meta-analysis: Chlorthalidone vs. hydrochlorothiazide

Large Observational Study Suggests Hydrochlorothiazide may be as Effective as Chlortalidone with Less Adverse Effects

Commentary on Twitter

There are big differences among diuretics even within the same class. So let us rethink the class effect. https://t.co/ruE4IYeFf2. Here I discuss what we know about HCTZ vs CTD. pic.twitter.com/cyljdi04v9

— Rajiv Agarwal MD, MS (@AgarwalRajivMD) October 8, 2022