Family Medicine

M-A | Association of SGLT2 inhibitors with cardiovascular outcomes and safety events.

1 Nov, 2022 | 11:56h | UTC

Association of sodium-glucose cotransporter 2 inhibitors with cardiovascular outcome and safety events: A meta-analysis of randomized controlled clinical trials – Frontiers in Cardiovascular Medicine

 

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ACC Expert consensus for integrating atherosclerotic cardiovascular disease and multimorbidity treatment.

31 Oct, 2022 | 13:59h | UTC

2022 ACC Expert Consensus Decision Pathway for Integrating Atherosclerotic Cardiovascular Disease and Multimorbidity Treatment: A Framework for Pragmatic, Patient-Centered Care: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Commentary: American College of Cardiology shares expert analysis on treating ASCVD patients with multiple chronic conditions – Cardiovascular Business

 

Commentary on Twitter

.@ACCinTouch's newest Expert Consensus Decision Pathway, just published in #JACC, offers a comprehensive and integrative framework for treating patients with #ASCVD and multimorbidity. https://t.co/NAa1aP4OEx#ACCClinicalDoc #CardioTwitter @kofi_larry @virani_md @tygluckman pic.twitter.com/XPePHSwuFL

— JACC Journals (@JACCJournals) October 25, 2022

 

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M-A of RCT | Comparison of low carbohydrate vs. low fat diets in Type 2 DM.

31 Oct, 2022 | 13:55h | UTC

Comparison of the Effectiveness of Low Carbohydrate Versus Low Fat Diets, in Type 2 Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials – Nutrients

 

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SR | Immediate versus delayed postpartum insertion of contraceptive implant and IUD for contraception.

31 Oct, 2022 | 13:56h | UTC

Immediate versus delayed postpartum insertion of contraceptive implant and IUD for contraception – Cochrane Library

Summary: Is it better to insert an implant or intrauterine device (coil) for contraception within days of childbirth or wait 4 to 6 weeks? – Cochrane Library

 

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RCT | Effects of a low-carbohydrate dietary intervention on hemoglobin A1c.

31 Oct, 2022 | 13:54h | UTC

Effects of a Low-Carbohydrate Dietary Intervention on Hemoglobin A1c: A Randomized Clinical Trial – JAMA Network Open

See also: Visual Abstract

News Release: At risk for diabetes? Cut the carbs, says new study – Tulane University

Commentaries:

Expert reaction to study looking at effects of a low-carbohydrate dietary intervention and improved glycaemia – Science Media Centre

Low-Carb Diet Promising for Lowering Blood Sugar in Prediabetes – TCTMD

 

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Dose-reduced direct oral anticoagulants: practical considerations.

31 Oct, 2022 | 13:52h | UTC

Peripheral Matters | Dose-Reduced Direct Oral Anticoagulants: Practical Considerations – American College of Cardiology

 

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WHO Report | Fungal priority pathogens list to guide research, development and public health action.

28 Oct, 2022 | 13:31h | UTC

WHO fungal priority pathogens list to guide research, development and public health action – World Health Organization

News Release: WHO releases first-ever list of health-threatening fungi – World Health Organization

 

Commentary on Twitter (thread – click for more)

Fungal pathogens can cause illnesses and death.
They are becoming increasingly common and resistant to treatment.

Yet, too little is known about them.

The 🆕 WHO fungal priority pathogens list is an important step to boost urgently needed research:
📌 https://t.co/cXgj2HPZIc pic.twitter.com/4LgdIqf4Lo

— World Health Organization (WHO) (@WHO) October 25, 2022

 

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Systematic Review | Support for healthy breastfeeding mothers with healthy term babies.

28 Oct, 2022 | 13:23h | UTC

Support for healthy breastfeeding mothers with healthy term babies – Cochrane Library

Summary: Support for breastfeeding mothers – Cochrane Library

 

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CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox.

28 Oct, 2022 | 13:21h | UTC

Health Care Personnel Exposures to Subsequently Laboratory-Confirmed Monkeypox Patients — Colorado, 2022 – Morbidity and Mortality Weekly Report

Commentaries:

Clinicians at Low Risk of Acquiring Monkeypox From Patients – JAMA

Low risk of monkeypox spread noted in health workers – CIDRAP

Risk of Monkeypox Transmission Low in Health Care Settings – HealthDay

 

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Review | Monkeypox.

27 Oct, 2022 | 12:36h | UTC

Monkeypox – New England Journal of Medicine

Related:

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine

Monkeypox: disease epidemiology, host immunity and clinical interventions.

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 

Commentary on Twitter

Monkeypox cases reported in the United Kingdom, Portugal, and Italy in May 2022 led the WHO to declare a global health emergency. The authors review the virology, epidemiology, clinical features, and treatment of monkeypox. https://t.co/dk2ZxxPsN7 pic.twitter.com/u3gzD6V7Bo

— NEJM (@NEJM) October 26, 2022

 

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Cohort Study | Maternal hypertensive disorder of pregnancy and mortality in offspring from birth to young adulthood.

27 Oct, 2022 | 12:31h | UTC

Maternal hypertensive disorder of pregnancy and mortality in offspring from birth to young adulthood: national population based cohort study – The BMJ

News Release: Blood pressure disorder in pregnancy linked to heightened risk of death in offspring – BMJ Newsroom

 

Commentary on Twitter

NEW research: Maternal HDP, particularly eclampsia and severe pre-eclampsia, is associated with increased risks of overall mortality and various cause specific mortalities in offspring from birth to young adulthood https://t.co/kfczWFwzG5

— The BMJ (@bmj_latest) October 23, 2022

 

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Cohort Study | Cannabis, cocaine, methamphetamine, and opiates linked to increased risk of incident atrial fibrillation.

27 Oct, 2022 | 12:29h | UTC

Cannabis, cocaine, methamphetamine, and opiates increase the risk of incident atrial fibrillation – European Heart Journal

Editorial: Drug abuse and risk of atrial fibrillation: a neglected association – European Heart Journal

Commentaries:

Illicit drugs associated with increased likelihood of developing atrial fibrillation – European Society of Cardiology/News Medical

Marijuana, Meth, Cocaine Use Can Help Trigger Dangerous A-Fib – HealthDay

 

Commentary on Twitter

New study just published in EHJ suggests that cannabis, cocaine, methamphetamine, and opiates may increase the risk of incident atrial fibrillation: discover more!https://t.co/ySrmaLnacC#AF #methamphetamine #cocaine #opiate #cannabis #cardiotwitter @escardio @ESC_Journals pic.twitter.com/YCvqjPGQjG

— EHJ Editor-in-Chief (@ehj_ed) October 20, 2022

 

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Case-control study | Alcohol intake as a risk factor for acute stroke.

27 Oct, 2022 | 12:26h | UTC

Alcohol Intake as a Risk Factor for Acute Stroke: The INTERSTROKE Study – Neurology (PDF)

 

Commentary on Twitter

In this study, high and moderate alcohol intake were associated with increased odds of stroke, while low intake was not associated with #stroke. However, there were important regional variations. Read the full article: https://t.co/lrczN0KBmD #NeuroTwitter pic.twitter.com/95QXuwczEA

— Neurology Journal (@GreenJournal) October 19, 2022

 

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Review | Management of NAFLD in primary care settings.

27 Oct, 2022 | 12:24h | UTC

Management of NAFLD in primary care settings – Liver International

Related:

Updated S2k Clinical Practice Guideline on Non-alcoholic Fatty Liver Disease (NAFLD) issued by the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie

AGA Clinical Practice Update | Diagnosis and management of nonalcoholic fatty liver disease in lean individuals.

Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group – The Lancet Gastroenterology & Hepatology (free registration required)

Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association – Arteriosclerosis, Thrombosis, and Vascular Biology

Advancing the global public health agenda for NAFLD: a consensus statement – Nature Reviews Gastroenterology & Hepatology

Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease – Gastroenterology

Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports

 

Commentary on Twitter

Opportunities of assessment and treatment of #NAFLD in primary care settings

👉 https://t.co/cXJHFRiJVn

✍️ @VWSWong @DrJavierCrespo @JVLazarus #livertwitter #liverreviews #NASH pic.twitter.com/5SLqNvafAm

— Liver International (@LiverInt) October 23, 2022

 

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Review | Hypercalcemia.

26 Oct, 2022 | 14:37h | UTC

Hypercalcemia: A Review – JAMA (free for a limited period)

Author Interview: Hypercalcemia—A Review – JAMA

 

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Optimizing medication use in older adults with rheumatic diseases: deprescribing as an approach when less may be more.

26 Oct, 2022 | 14:33h | UTC

Optimizing Medication Use in Older Adults With Rheumatic Musculoskeletal Diseases: Deprescribing as an Approach When Less May Be More – ACP Open Rheumatology

Related:

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy – European Heart Journal – Cardiovascular Pharmacotherapy

Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology

Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology

Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis – Health Technology Assessment

Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports

How-to guide for medication reviews in older adults with cancer: A Young International Society of Geriatric Oncology and Nursing & Allied Health Interest Group initiative – Journal of Geriatric Oncology

Deprescribing in Palliative Cancer Care – Life

Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360

Process evaluation of implementation strategies to reduce potentially inappropriate medication prescribing in older population: A scoping review – Research in Social and Administrative Pharmacy

AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review – Gastroenterology

Development of a Metric to Detect and Decrease Low-Value Prescribing in Older Adults – JAMA Network Open

The MedSafer Study—Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial – JAMA Internal Medicine

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines – Supportive Care in Cancer

Prescribing practices, patterns, and potential harms in patients receiving palliative care: A systematic scoping review – Exploratory Research in Clinical and Social Pharmacy

A narrative review of evidence to guide deprescribing among older adults – Journal of General and Family Medicine

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens – The Lancet Health Longevity

Polypharmacy Management in Older Patients – Mayo Clinic Proceedings

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt international

Eliminating Medication Overload: A National Action Plan – Lown Institute

International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action – Drugs & Aging

Common ED Medication Errors: Polypharmacy – emDocs

Current and future perspectives on the management of polypharmacy – BMC Family Practice

Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety

Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international

Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety

 

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M-A | Age, sex, race, BMI, and duration of type 2 DM differences in cardiovascular outcomes with glucose lowering drugs.

26 Oct, 2022 | 14:32h | UTC

Age, sex, race, BMI, and duration of diabetes differences in cardiovascular outcomes with glucose lowering drugs in type 2 diabetes: A systematic review and meta-analysis – eClinicalMedicine

Commentary: Meta-analysis may guide optimal type 2 diabetes glucose-lowering agent for MACE protection – medwire News

 

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M-A | Non-pharmacologic and pharmacologic treatments for anxiety in long-term care.

26 Oct, 2022 | 14:26h | UTC

Non-pharmacologic and pharmacologic treatments for anxiety in long-term care: a systematic review and meta-analysis – Age and Ageing

 

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ASMBS Guidelines | Indications for metabolic and bariatric surgery.

24 Oct, 2022 | 14:17h | UTC

2022 American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO): Indications for Metabolic and Bariatric Surgery – Surgery for Obesity and Related Diseases

News Release: After 30 years — new guidelines for weight-loss surgery – American Society for Metabolic and Bariatric Surgery

Commentary: New guidelines expand eligibility for weight loss surgery. Will insurance coverage follow? – USA Today

 

Commentary on Twitter

✴️ Updated Indictions of #BariatricSurgery for treating #obesity by @ASMBS @IfsoSecretariat https://t.co/TrTcCEu0q1 pic.twitter.com/c5s15FmXpp

— Ali Aminian (@Ali_Aminian_MD) October 21, 2022

 

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KDIGO 2022 Clinical practice guideline for diabetes management in chronic kidney disease.

24 Oct, 2022 | 14:16h | UTC

KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease – Kidney International

See also: Executive summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: an update based on rapidly emerging new evidence – Kidney International

Related: ADA/KDIGO Consensus Report | Diabetes management in chronic kidney disease.

 

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RCT | Ivermectin does not improve time to recovery in outpatients with mild to moderate COVID-19.

24 Oct, 2022 | 14:14h | UTC

Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial – JAMA

Commentary: Ivermectin doesn’t speed time to recovery from nonsevere COVID – CIDRAP

 

Commentary on Twitter

Study findings do not support the use of #ivermectin in outpatients with mild to moderate #COVID19. https://t.co/do8zbVkeLK #Research

— JAMA (@JAMA_current) October 21, 2022

 

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Conservative interventions for treating urinary incontinence in women: an overview of Cochrane systematic reviews.

24 Oct, 2022 | 14:13h | UTC

Conservative interventions for treating urinary incontinence in women: an Overview of Cochrane systematic reviews – Cochrane Library

Summary: Conservative interventions for urinary incontinence in women: an overview of Cochrane Reviews – Cochrane Library

 

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Systematic Review | Antidepressants for hip and knee osteoarthritis.

24 Oct, 2022 | 14:04h | UTC

Antidepressants for hip and knee osteoarthritis – Cochrane Library

 

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Systematic Review | Systemic corticosteroids for radicular and non‐radicular low back pain.

24 Oct, 2022 | 14:03h | UTC

Systemic corticosteroids for radicular and non‐radicular low back pain – Cochrane Library

 

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Cohort Study | Women with schizophrenia-spectrum disorders are at increased risk of relapse after menopause.

24 Oct, 2022 | 13:59h | UTC

Women with Schizophrenia-Spectrum Disorders After Menopause: A Vulnerable Group for Relapse – Schizophrenia Bulletin

 

Commentary on Twitter

cohort study: Starting at age 45–50, women were consistently more often hospitalized for psychosis than their male peers. Women ≥45 had significantly higher aHRs than women <45 at antipsychotic monotherapy >0.6 DDDs/day, and than men at >1.1 DDDs/day https://t.co/YYINatGD0O pic.twitter.com/7xWmAnt72q

— P𝘧OL (@psychopharmacol) October 7, 2022

 

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