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Endocrinology (all articles)

Can COVID-19 cause diabetes?

19 Jan, 2021 | 01:48h | UTC

Can COVID-19 cause diabetes? – Nature Reviews Endocrinology

Related: COVID-19 and diabetes mellitus: from pathophysiology to clinical management – Nature Reviews Endocrinology

 

Commentary on Twitter

 


Study: Sweetened beverage sales decreased after new tax implementation and bounced back quickly after the tax was repealed

19 Jan, 2021 | 01:24h | UTC

Evaluation of Changes in Beverage Prices and Volume Sold Following the Implementation and Repeal of a Sweetened Beverage Tax in Cook County, Illinois – JAMA Network Open

Commentaries: Sweetened beverage sales bounced back quickly after Cook County tax repealed – University of Illinois at Chicago AND Is the Association Between Beverage Taxes and Reductions in Sales Driven by Communication of Health Consequences in Addition to Price Increases? – JAMA Network Open

 

Commentaries on Twitter

https://twitter.com/Neena_P/status/1344090204626366465

 


Meta-analysis: The effect of low-fat and low-carbohydrate diets on weight loss and lipid levels

19 Jan, 2021 | 01:18h | UTC

The Effect of Low-Fat and Low-Carbohydrate Diets on Weight Loss and Lipid Levels: A Systematic Review and Meta-Analysis – Nutrients

 


Systematic review: Time-restricted eating’s effects on human health

19 Jan, 2021 | 01:16h | UTC

Food Timing, Circadian Rhythm and Chrononutrition: A Systematic Review of Time-Restricted Eating’s Effects on Human Health – Nutrients

 


Meta-analysis of randomized trials: patients adhering to a low carbohydrate diet for six months may experience remission of diabetes without adverse consequences

15 Jan, 2021 | 08:43h | UTC

Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished randomized trial data – The BMJ

Commentary: Short term low carbohydrate diet linked to remission of type 2 diabetes – The BMJ

 

 


Meta-analysis of randomized trials: SGLT-2 inhibitors and GLP-1 receptor agonists reduce cardiovascular and renal outcomes in type 2 diabetes

15 Jan, 2021 | 08:41h | UTC

Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials – The BMJ

Calculator based on the results: interactive decision support tool for outcomes

 


Study: Despite recommendations, less than 2 percent of patients with treatment-resistant hypertension were tested for primary aldosteronism in a large U.S. cohort

14 Jan, 2021 | 01:55h | UTC

Testing for Primary Aldosteronism and Mineralocorticoid Receptor Antagonist Use Among U.S. Veterans: A Retrospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Primary Aldosteronism Testing Rare in Treatment-Resistant HTN – HealthDay AND Primary Aldosteronism Testing Rare for Patients with Resistant Hypertension – NEJM Journal Watch

 

Commentary from the author on Twitter (thread – click for more)

 


Systematic review into city interventions to address obesity

14 Jan, 2021 | 01:50h | UTC

Systematic review into city interventions to address obesity – EClinicalMedicine

 


New Guidance for Type 1 Diabetes Continuous Glucose Monitoring Use During Exercise

12 Jan, 2021 | 01:40h | UTC

New Guidance for Type 1 Diabetes Continuous Glucose Monitoring Use During Exercise – JAMA

Original Guideline: Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA) – Diabetologia

 


Observational study: Childhood growth hormone treatment linked to increased risks of cardiovascular events in early adulthood

10 Jan, 2021 | 20:27h | UTC

Association of Childhood Growth Hormone Treatment With Long-term Cardiovascular Morbidity – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: Childhood Tx with Growth Hormone May Up Cardiovascular Risks Later – Physician’s Weekly AND Growth Hormones in Childhood Tied to Heart Problems Later On – MedPage Today (free registration required)

 


Effects of low sodium diet vs. high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride

10 Jan, 2021 | 20:12h | UTC

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride – Cochrane Library

Summary: The effect of a low salt diet on blood pressure and some hormones and lipids in people with normal and elevated blood pressure – Cochrane Library

 


Guideline: ADA 2021 Standards of Medical Care in Diabetes

10 Dec, 2020 | 00:11h | UTC

Just published! New ADA 2022 Guideline for the Management of Diabetes

Guideline Homepage: ADA 2021 Standards of Medical Care in Diabetes – American Diabetes Association (free supplement)

 

See ADA 2021 Guideline topics below:

 

Introduction: Standards of Medical Care in Diabetes—2021

Summary of Revisions: Standards of Medical Care in Diabetes—2021

 

  1. Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes—2021
  2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2021
  3. Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2021
  4. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2021
  5. Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2021
  6. Glycemic Targets: Standards of Medical Care in Diabetes—2021
  7. Diabetes Technology: Standards of Medical Care in Diabetes—2021
  8. Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2021
  9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2021
  10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2021
  11. Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes—2021
  12. Older Adults: Standards of Medical Care in Diabetes—2021
  13. Children and Adolescents: Standards of Medical Care in Diabetes—2021
  14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2021
  15. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2021
  16. Diabetes Advocacy: Standards of Medical Care in Diabetes—2021

 

Commentary on Twitter

 


AHA Scientific Statement: Menopause transition and cardiovascular disease risk

15 Dec, 2020 | 01:32h | UTC

Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association – Circulation

News release: Heart disease risk in women increases leading up to menopause; early intervention is key – American Heart Association

Top Things to Know: Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention

Commentaries: Menopause Transition and Cardiovascular Health: Time Matters – American Heart Association AND Report on latest menopause science looks at heart risks – American Heart Association AND Menopause Transition and CVD Risk: AHA Scientific Statement – American College of Cardiology

 


Randomized trial: No difference in quality of life and slightly greater weight loss with Roux-en-Y Gastric Bypass compared to Laparoscopic Sleeve Gastrectomy at 7 years

11 Dec, 2020 | 09:20h | UTC

Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss and Quality of Life at 7 Years in Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Using Quality-of-Life Measures to Determine the Ideal Bariatric Procedure – JAMA Surgery (free for a limited period)

 


Randomized trial: No benefit and potential harm from Vitamin D at doses of 1000 IU/d or higher compared with 200 IU/d in older persons with elevated fall risk

9 Dec, 2020 | 08:13h | UTC

The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults: A Response-Adaptive, Randomized Clinical Trial – Annals of Internal Medicine

Commentaries: Study Finds No Benefit, Possible Harm to Seniors’ Fall Risks with Higher Doses of Vitamin D – Johns Hopkins Medicine AND Does High-Dose Vitamin D Actually Heighten Fall Risk? – Physician’s Weekly

 

Commentary on Twitter (thread – click for more)

https://twitter.com/ErinMichos/status/1336091776994537472

 


Cohort study: In the general population, both low and high levels of LDL cholesterol were associated with an increased risk of all-cause mortality

9 Dec, 2020 | 08:11h | UTC

Association between low density lipoprotein and all cause and cause specific mortality in Denmark: prospective cohort study – The BMJ

 

Commentary on Twitter

 


Randomized trial: A low-fat vegan diet can reduce body weight and improve insulin sensitivity in overweight adults

2 Dec, 2020 | 07:16h | UTC

Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults: A Randomized Clinical Trial – JAMA Network Open

Commentary: Plant-based diet ramps up metabolism, according to new study – Physicians Committee for Responsible Medicine

 


Meta-analysis of statins for primary prevention: 100 adults (aged 50-75 years) without known cardiovascular disease would have to be treated for 2.5 years to prevent 1 major adverse cardiovascular event

30 Nov, 2020 | 00:56h | UTC

Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years: A Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Time to Benefit of Statins for Primary Prevention of Cardiovascular Events – American College of Cardiology

 

Commentary on Twitter

 


Practice recommendations for the management of the most common forms of secondary hypertension, including primary aldosteronism, renovascular hypertension, pheochromocytoma, Cushing’s syndrome, and sleep apnea

26 Nov, 2020 | 08:59h | UTC

Practice Recommendations for Diagnosis and Treatment of the Most Common Forms of Secondary Hypertension – High Blood Pressure & Cardiovascular Prevention

 


Podcast: Diabetes Triple Distilled. Pitfalls of A1c testing, different guidelines for A1C targets, when and how to use the newer medications such as SGLT-2 inhibitors and GLP-1 agonists, and more

24 Nov, 2020 | 09:03h | UTC

#243 Diabetes Triple Distilled – The Curbsiders Internal Medicine Podcast

 


Systematic review: Ultra-long‐acting insulins provide modest benefit compared to NPH insulin for Type 2 DM, resulting in reduced risk of hypoglycemia but no difference in HbA1c

23 Nov, 2020 | 09:45h | UTC

(Ultra‐)long‐acting insulin analogues versus NPH insulin (human isophane insulin) for adults with type 2 diabetes mellitus – Cochrane Library

Summary: (Ultra-)long-acting insulin analogues compared with NPH insulin (human isophane insulin) for adults with type 2 diabetes mellitus

 


#AHA20 – RCT: Sotagliflozin improved cardiovascular outcomes in patients with Diabetes and CKD. Diarrhea, genital mycotic infections, volume depletion, and diabetic ketoacidosis were more common with sotagliflozin than with placebo

18 Nov, 2020 | 09:08h | UTC

Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk – SCORED – American College of Cardiology

 


#AHA20 – RCT: Sotagliflozin improved cardiovascular outcomes in patients with Diabetes and Recent Worsening Heart Failure. Diarrhea and severe hypoglycemia were more common with sotagliflozin than with placebo

18 Nov, 2020 | 09:06h | UTC

Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure – SOLOIST-WHF – American College of Cardiology

 


Opinion: A new important study supports wider use of the polypill

18 Nov, 2020 | 09:01h | UTC

Richard Smith: A new important study supports wider use of the polypill – The Lancet

Original study and commentaries: Randomized trial: A polypill comprising statins, multiple blood pressure lowering drugs, and aspirin prevents cardiovascular events among patients at intermediate cardiovascular risk

 

Commentary on Twitter

 


[Abstract Only] In a Phase 2 randomized trial, Semaglutide at high doses improved Nonalcoholic Steatohepatitis (NASH), but with no significant beneficial effects in liver fibrosis

17 Nov, 2020 | 09:31h | UTC

A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Semaglutide Shows Promise in NASH Phase 2 Study – Medscape (free registration required)

 

Commentary on Twitter

https://twitter.com/NEJM/status/1327238536001593346

 


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