Open access
Open access
Powered by Google Translator Translator

Editor's Choice

RCT | Tamponade dressing does not reduce bleeding or pain compared to no dressing after hemorrhoidectomy.

10 Nov, 2022 | 14:06h | UTC

Tamponade dressing versus no dressing after haemorrhoidectomy: multicentre, randomized clinical trial – BJS Open

 

Commentary on Twitter

 

Guideline | Intravenous maintenance fluid therapy in acute and critically ill children.

9 Nov, 2022 | 12:32h | UTC

ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis – Intensive Care Medicine

 

Commentary on Twitter

 

AHA Scientific Statement | Arrhythmias in repaired Tetralogy of Fallot.

9 Nov, 2022 | 12:33h | UTC

Arrhythmias in Repaired Tetralogy of Fallot: A Scientific Statement From the American Heart Association – Circulation: Arrhythmia and Electrophysiology

Summary: Arrhythmias in Repaired Tetralogy of Fallot – American Heart Association

Top Things to Know: Arrhythmias in Repaired Tetralogy of Fallot – American Heart Association

Commentary: Challenges in Managing Arrhythmias in Adult Tetralogy of Fallot – American Heart Association

 

RCT | Using an algorithm to stratify the risk of patients with acute heart failure may improve outcomes.

9 Nov, 2022 | 12:30h | UTC

Trial of an Intervention to Improve Acute Heart Failure Outcomes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: New Tool Assesses Risk in Acute HF Then Suggests Next Steps, Cutting Later Events – TCTMD

 

Commentary on Twitter

 

RCT | In infants undergoing heart surgery, prophylactic methylprednisolone did not significantly improve outcomes.

9 Nov, 2022 | 12:31h | UTC

Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Steroids during surgery may not be helpful for infants having heart bypass – American Heart Association

 

Commentary on Twitter

 

Study Commentary | Radial artery beats both right internal thoracic artery and vein grafting at 15 years.

9 Nov, 2022 | 12:28h | UTC

(Not published yet, presented at the American Heart Association Scientific Sessions, November 6, 2022)

RAPCO: Radial Artery Beats Both RITA and Vein Grafting at 15 Years – TCTMD

See also:

Radial Artery Patency and Clinical Outcomes Study–Right Internal Thoracic Artery – RAPCO-RITA – American College of Cardiology

Radial Artery Patency and Clinical Outcomes Study–Saphenous Vein – RAPCO-SV – American College of Cardiology

Related:

Meta-analysis: Radial artery graft vs. saphenous vein graft in long-term cardiovascular outcomes among patients undergoing coronary artery bypass grafting

Meta-Analysis: Radial-Artery vs Saphenous-Vein Grafts in CABG

 

M-A | DOACs increase the risk of arterial thrombosis vs. Vitamin-K antagonists in antiphospholipid syndrome.

9 Nov, 2022 | 12:28h | UTC

Direct Oral Anticoagulants vs Vitamin-K Antagonists in Thrombotic Antiphospholipid Syndrome: Meta-analysis of Randomized Controlled Trials – Journal of the American College of Cardiology (link to abstract – $ for full-text)

 

RCT | Effect of text messaging parents of school-aged children on outdoor time to control myopia.

9 Nov, 2022 | 12:26h | UTC

Effect of Text Messaging Parents of School-Aged Children on Outdoor Time to Control Myopia: A Randomized Clinical Trial – JAMA Pediatrics

 

Commentary on Twitter

 

Canadian guideline for the prevention and management of cardiovascular disease in primary care.

8 Nov, 2022 | 12:37h | UTC

Canadian Cardiovascular Harmonized National Guideline Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2022 update – Canadian Medical Association Journal

News Release: New one-stop guideline for cardiovascular health in Canada – Canadian Medical Association Journal

 

NICE Guideline | Obesity: identification, assessment and management.

8 Nov, 2022 | 12:35h | UTC

Obesity: identification, assessment and management – National Institute for Health and Care Excellence

Related:

Keep the size of your waist to less than half of your height, updated NICE draft guideline recommends.

ASMBS Guidelines | Indications for metabolic and bariatric surgery.

AGA clinical practice guideline on pharmacological interventions for adults with obesity.

Guideline | Preventing obesity in midlife women.

ADA Guideline Summary | Obesity and weight management for prevention and treatment of Type 2 Diabetes.

 

Follow-up of the ISCHEMIA trial | Similar survival after invasive vs. conservative management of stable coronary disease.

8 Nov, 2022 | 12:32h | UTC

Survival After Invasive or Conservative Management of Stable Coronary Disease – Circulation (free for a limited period)

Original Articles:

ISCHEMIA Trial: Health-Status Outcomes with Initial Invasive vs. Conservative Care in Stable Coronary Disease

ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease

ISCHEMIA Trial: Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease

ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease

See also:

RCT | In patients with severe ischemic left ventricular systolic dysfunction under optimal medical therapy, revascularization by PCI did not improve outcomes.

 

Commentary on Twitter

 

RCT | In patients with paroxysmal, untreated AF, cryoballoon ablation reduced recurrence compared to drug therapy.

8 Nov, 2022 | 12:29h | UTC

Progression of Atrial Fibrillation after Cryoablation or Drug Therapy – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

RCT | Surgery reduced major adverse limb events vs. endovascular therapy in patients with chronic limb-threatening ischemia.

8 Nov, 2022 | 12:34h | UTC

Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Bypass surgery favorable for initial treatment of chronic limb-threatening ischemia – National Institutes of Health

 

Commentary on Twitter

https://twitter.com/NEJM/status/1589621195632439296

 

Phase 2 RCT | Small interfering RNA to reduce Lipoprotein(a) in cardiovascular disease.

8 Nov, 2022 | 12:30h | UTC

Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Clinical trial finds novel therapy markedly reduced lipoprotein(a) levels in people with cardiovascular disease – Brigham and Women’s Hospital

 

Commentary on Twitter

 

RCT | New defibrillation strategies increased the rates of survival to hospital discharge in patients with refractory ventricular fibrillation.

8 Nov, 2022 | 12:27h | UTC

Defibrillation Strategies for Refractory Ventricular Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: “Double shock” from two defibrillators could save more lives – Heart & Stroke

 

Commentary on Twitter

 

RCT | Rapid up-titration of guideline-directed medical therapies for acute heart failure reduced readmissions and deaths.

8 Nov, 2022 | 12:24h | UTC

Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial – The Lancet (free registration required)

News Release: Maximizing heart failure meds within 2 weeks reduced risk of hospital readmission, death – American Heart Association

Commentary: STRONG-HF: Rapid Uptitration of GDMT After Acute HF Pays Dividends – TCTMD

 

RCT | After an out-of-hospital cardiac arrest, fever prevention for 36 vs. 72 hours resulted in similar outcomes.

8 Nov, 2022 | 12:23h | UTC

Duration of Device-Based Fever Prevention after Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

CDC Clinical Practice Guideline for prescribing opioids for pain.

7 Nov, 2022 | 13:00h | UTC

CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 – Morbidity and Mortality Weekly Report

Commentaries:

Prescribing Opioids for Pain — The New CDC Clinical Practice Guideline – New England Journal of Medicine

CDC issues new opioid prescribing guidance, giving doctors more leeway to treat pain – NPR

 

NICE Guideline | Self-harm: assessment, management and preventing recurrence.

7 Nov, 2022 | 12:58h | UTC

Self-harm: assessment, management and preventing recurrence – National Institute for Health and Care Excellence

 

RCT | In patients with CKD (eGFR 20-45 mL/min per 1.73 m2), Empagliflozin reduced the risk of progression of kidney disease.

7 Nov, 2022 | 12:56h | UTC

Empagliflozin in Patients with Chronic Kidney Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: EMPA-KIDNEY supports SGLT2 inhibition for chronic kidney disease – medwire News

Video Summary: EMPA-KIDNEY results: Empagliflozin reduces kidney disease progression and cardiovascular deaths

 

Commentary on Twitter

 

RCT | Triglyceride lowering with Pemafibrate fails to reduce CVD risk in patients with Type 2 DM and hypertriglyceridemia.

7 Nov, 2022 | 12:54h | UTC

Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk – New England Journal of Medicine (link to abstract – $ for full-text)

News Releases:

New medicine reduces triglyceride by 25%, no change in CVD risk in people with Type 2 diabetes – American Heart Association

Triglyceride-lowering trial neutral for cardiovascular event reduction – Brigham and Women’s Hospital

Commentaries:

Pemafibrate Fails to Lower CVD Risk in Patients With High Triglycerides: PROMINENT – TCTMD

PROMINENT: Pemafibrate Effective in Lowering Tryglycerides, But Not Reducing Risk of CV Events – American College of Cardiology

 

Commentary on Twitter

 

RCT | Early amino acids in extremely preterm infants did improve neurodisability at 2 Years.

7 Nov, 2022 | 12:52h | UTC

Early Amino Acids in Extremely Preterm Infants and Neurodisability at 2 Years – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Extra Parenteral Amino Acids No Benefit for Extremely Preterm Infants – HealthDay

 

Commentary on Twitter

 

RCT | Chlortalidone and Hydrochlorothiazide resulted in similar reductions of CVD in older patients with hypertension.

7 Nov, 2022 | 12:50h | UTC

News Release (not published yet): No difference in heart outcomes found in use of two diuretics to treat blood pressure – American Heart Association

Commentaries:

In High BP, Chlorthalidone and Hydrochlorothiazide Have Similar Impact on MACE – TCTMD

Diuretic Comparison Project – DCP – American College of Cardiology

 

RCT | Intravenous iron did not significantly reduce hospital admissions in patients with heart failure and iron deficiency.

7 Nov, 2022 | 12:48h | UTC

Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial – The Lancet

Commentaries:

Effectiveness of Intravenous Iron Treatment Versus Standard Care in Patients With Heart Failure and Iron Deficiency – IRONMAN – American College of Cardiology

IRONMAN Misses but Lends Support to IV Iron Repletion in HF – TCTMD

 

Cohort Study | Preoperative hemodialysis timing and postoperative mortality in patients with end-stage kidney disease.

7 Nov, 2022 | 12:46h | UTC

Association Between Preoperative Hemodialysis Timing and Postoperative Mortality in Patients With End-stage Kidney Disease – JAMA (free for a limited period)

Editorial: Optimal Timing of Hemodialysis Before Surgery – JAMA (free for a limited period)

 

Commentary from the author on Twitter (thread – click for more)

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.