RCT | In infants undergoing heart surgery, prophylactic methylprednisolone did not significantly improve outcomes.

Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Steroids during surgery may not be helpful for infants having heart bypass – American Heart Association

Commentary on Twitter

In this randomized, controlled trial involving infants undergoing surgery with cardiopulmonary bypass, prophylactic use of methylprednisolone did not significantly reduce the likelihood of a worse outcome. #AHA22 https://t.co/jaza6JCAuk pic.twitter.com/lLrxci7SaE

— NEJM (@NEJM) November 6, 2022