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Critical Care & Emergencies (all articles)

RCT: In patients with cardiogenic shock receiving VA-ECMO, moderate hypothermia did not significantly reduce 30-day mortality. 42% of patients in the moderate hypothermia group died vs. 51% in the normothermia group (adjusted odds ratio, 0.71 [95% CI, 0.45 to 1.13], P = .15).

13 Feb, 2022 | 22:11h | UTC

Effect of Moderate Hypothermia vs Normothermia on 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentary: Hypothermia vs. Normothermia for Cardiogenic Shock Patients on VA-ECMO – American College of Cardiology

 

Commentary on Twitter

 


Opinion: Time to retire the concept of Transient Ischemic Attack.

13 Feb, 2022 | 22:01h | UTC

Time to Retire the Concept of Transient Ischemic Attack – JAMA (free for a limited period)

 

Commentary on Twitter

 


Sleep assessment in critically ill adults: established methods and emerging strategies.

13 Feb, 2022 | 21:55h | UTC

Sleep Assessment in Critically Ill Adults: Established Methods and Emerging Strategies – Critical Care Explorations

 

Commentary on Twitter

 


Review: Management of venous thromboembolism in pregnancy.

13 Feb, 2022 | 21:57h | UTC

Management of venous thromboembolism in pregnancy – Thrombosis Research

Related:

Management of high-risk pulmonary embolism in pregnancy.

Study: Diagnosis of Pulmonary Embolism During Pregnancy

Imaging is the only way to diagnose blood clots in pregnancy

Prevention and Treatment of Pregnancy-Associated Venous Thromboembolism: Critical Appraisal of International Guidelines

 


ED management of the post-laryngectomy patient.

13 Feb, 2022 | 21:44h | UTC

ED Management of the Post-Laryngectomy Patient – emDocs

 


IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections.

11 Feb, 2022 | 08:51h | UTC

IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections – Clinical Microbiology and Infection

Original Guidelines:

European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

 


RCT: In patients with acute stroke with a large ischemic region, endovascular therapy resulted in better functional outcomes compared to medical care alone but was associated with increased risk of intracranial hemorrhage.

11 Feb, 2022 | 08:49h | UTC

Endovascular Therapy for Acute Stroke with a Large Ischemic Region – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Endovascular Stroke Therapy Works for Large Infarcts: RESCUE-Japan LIMIT – TCTMD

 


AHA Scientific Statement: Identifying best practices to improve evaluation and management of in-hospital stroke.

10 Feb, 2022 | 10:13h | UTC

Identifying Best Practices to Improve Evaluation and Management of In-Hospital Stroke: A Scientific Statement From the American Heart Association – Stroke

News Release: Five elements to optimize treatment of in-hospital stroke – American Heart Association

 

Commentary on Twitter

 


IDSA Updated Covid-19 Guideline now supports the use of convalescent plasma in ambulatory patients with mild to moderate COVID-19 at high risk for progression to severe disease.

9 Feb, 2022 | 10:15h | UTC

IDSA Guidelines on the Treatment and Management of Patients with COVID-19 – Infectious Diseases Society of America

Related: [Preprint] RCT: In symptomatic adults above 18 years positive for SARS-CoV-2, early outpatient treatment with high-titer convalescent plasma significantly reduced hospitalizations.

 

Commentary on Twitter

 


European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

9 Feb, 2022 | 10:18h | UTC

European Society of clinical microbiology and infectious diseases (ESCMID) guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli (endorsed by ESICM –European Society of intensive care Medicine) – Clinical Microbiology and Infection

Related: IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

 


The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022.

9 Feb, 2022 | 08:46h | UTC

The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022 – American Journal of Kidney Diseases

 


Review: Supraventricular arrhythmia in pregnancy.

9 Feb, 2022 | 08:38h | UTC

Supraventricular arrhythmia in pregnancy – Heart

 


Review | Prehospital plasma transfusion: what does the literature show?

9 Feb, 2022 | 08:22h | UTC

Prehospital Plasma Transfusion: What Does the Literature Show? – Transfusion Medicine and Hemotherapy

 


Review | Emergency blood transfusion for trauma and perioperative resuscitation.

9 Feb, 2022 | 08:22h | UTC

Emergency Blood Transfusion for Trauma and Perioperative Resuscitation: Standard of Care – Transfusion Medicine and Hemotherapy

 


Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation.

7 Feb, 2022 | 08:56h | UTC

Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation – The American Journal of Emergency Medicine

 


ERC-ESICM guidelines on temperature control after cardiac arrest in adults.

7 Feb, 2022 | 08:44h | UTC

ERC-ESICM guidelines on temperature control after cardiac arrest in adults – Intensive Care Medicine (if the link is paywalled, try this one)

Related:

M-A: In comatose survivors of cardiac arrest, targeted hypothermia is not associated with improved survival or better neurological outcomes vs. targeted normothermia.

RCT: In comatose survivors of out-of-hospital cardiac arrest, there was no difference in mortality and neurologic outcomes with mild (target temperature of 34 °C) vs. moderate therapeutic hypothermia (target temperature of 31 °C).

M-A: Targeted temperature management following out-of-hospital cardiac arrest – “Routine use of moderate or deep hypothermia in comatose survivors of OHCA may potentially be associated with more harm than benefit”.

RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

 

Commentary on Twitter

 


M-A: Tranexamic acid in aneurysmal subarachnoid hemorrhage does not improve clinical outcomes or mortality.

7 Feb, 2022 | 08:26h | UTC

Efficacy and safety of tranexamic acid in aneurysmal subarachnoid hemorrhage: A meta-analysis of randomized controlled trials – The American Journal of Emergency Medicine (link to abstract – $ for full-text)

 


M-A: The effect of Dexmedetomidine as a sedative agent for mechanically ventilated patients with sepsis.

7 Feb, 2022 | 08:15h | UTC

The Effect of Dexmedetomidine as a Sedative Agent for Mechanically Ventilated Patients With Sepsis: A Systematic Review and Meta-Analysis – Frontiers in Medicine

 


Does my hospitalized patient need an NPO-after-midnight order preoperatively?

4 Feb, 2022 | 09:58h | UTC

Does my hospitalized patient need an NPO-after-midnight order preoperatively? – Cleveland Clinic Journal of Medicine

Related:

ESPEN practical guideline: Clinical nutrition in surgery – “Preoperative fasting from midnight is unnecessary in most patients. Patients undergoing surgery, who are considered to have no specific risk of aspiration, shall drink clear fluids until 2 h before anesthesia. Solids shall be allowed until 6 h before anesthesia.”

Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.

Editorial: The rationale for the recommendations of the European Pediatric Fasting Guideline – “the authors of the 2021 ESAIC pediatric guideline have found reasons to recommend reductions to the minimum fasting times for infant formula to 4 h, for breast milk to 3 h and for clear fluids to 1 h”.

 


Consensus Statement: Preoperative Management of Medications for Neurologic Diseases.

4 Feb, 2022 | 10:00h | UTC

Preoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings

Related: Consensus Statement: Preoperative management of medications for psychiatric diseases.

 


Anaphylaxis: Highlights from the practice parameter update.

4 Feb, 2022 | 08:43h | UTC

Anaphylaxis: Highlights from the practice parameter update – Cleveland Clinic Journal of Medicine

Original Article: Anaphylaxis—a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis – Journal of Allergy and Clinical Immunology

 


Podcast: Infective Endocarditis Pearls.

4 Feb, 2022 | 08:27h | UTC

Infective Endocarditis Pearls – The Curbsiders

 


Thrombolytic use for STEMI: what ED clinicians should know.

4 Feb, 2022 | 08:23h | UTC

Thrombolytic Use for STEMI: What ED Clinicians Should Know – emDocs

 


Perspective: The origins, development, and context of the Lancet Commission on the Value of Death – “Death has turned from being a family, social, and cultural event to primarily a medical event”.

3 Feb, 2022 | 08:51h | UTC

The origins, development, and context of the Lancet Commission on the Value of Death – The BMJ

Related: The Lancet Commission: Experts warn of the increasing overmedicalization of death, call for radical rethink of how society cares for dying people.

 


Cluster randomized controlled trial: An innovative telemedical network to improve infectious disease management in critically ill patients and outpatients.

3 Feb, 2022 | 08:53h | UTC

An innovative telemedical network to improve infectious disease management in critically ill patients and outpatients: a stepped-wedge, cluster randomized controlled trial (TELnet@NRW) – Journal of Medical Internet Research

Related:

The “Choosing Wisely” initiative in infectious diseases – German Society of Infectious Diseases (link to abstract – $ for full-text)

Infectious Diseases Society of America: Five Things Physicians and Patients Should Question

 


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