Critical Care & Emergencies (all articles)
RCT: In patients with cardiogenic shock receiving VA-ECMO, moderate hypothermia did not significantly reduce 30-day mortality. 42% of patients in the moderate hypothermia group died vs. 51% in the normothermia group (adjusted odds ratio, 0.71 [95% CI, 0.45 to 1.13], P = .15).
13 Feb, 2022 | 22:11h | UTCEffect of Moderate Hypothermia vs Normothermia on 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Hypothermia vs. Normothermia for Cardiogenic Shock Patients on VA-ECMO – American College of Cardiology
Commentary on Twitter
In this RCT, for patients with cardiogenic shock receiving venoarterial ECMO, moderate hypothermia for 24 hours compared with normothermia did not significantly decrease 30-day mortality. https://t.co/0LKYJ1bNB3 pic.twitter.com/KmXPAlvqh9
— JAMA (@JAMA_current) February 2, 2022
Opinion: Time to retire the concept of Transient Ischemic Attack.
13 Feb, 2022 | 22:01h | UTCTime to Retire the Concept of Transient Ischemic Attack – JAMA (free for a limited period)
Commentary on Twitter
After spending my entire career studying TIAs, Don Easton and I are recommending we retire the term. It isn't clear that TIAs ever existed, at least as they were conceptualized. Rise up Acute Ischemic Cerebrovascular Event/Syndrome. https://t.co/FeG31pPHey
— Clay Johnston (@ClayJohnstonMD) February 11, 2022
Sleep assessment in critically ill adults: established methods and emerging strategies.
13 Feb, 2022 | 21:55h | UTC
Commentary on Twitter
#CritCareExplore @SCCM Critically ill patients sleep poorly while in the ICU with potential implications for several important outcomes. This review summarizes both current methods and new strategies to measure sleep in these challenging environments. https://t.co/2jtpHe4MKp pic.twitter.com/c5jnqwR3Mh
— Critical Care Explorations (@CritCareExplore) February 12, 2022
Review: Management of venous thromboembolism in pregnancy.
13 Feb, 2022 | 21:57h | UTCManagement of venous thromboembolism in pregnancy – Thrombosis Research
Related:
Management of high-risk pulmonary embolism in pregnancy.
Study: Diagnosis of Pulmonary Embolism During Pregnancy
Imaging is the only way to diagnose blood clots in pregnancy
ED management of the post-laryngectomy patient.
13 Feb, 2022 | 21:44h | UTCED Management of the Post-Laryngectomy Patient – emDocs
IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections.
11 Feb, 2022 | 08:51h | UTCOriginal Guidelines:
IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.
RCT: In patients with acute stroke with a large ischemic region, endovascular therapy resulted in better functional outcomes compared to medical care alone but was associated with increased risk of intracranial hemorrhage.
11 Feb, 2022 | 08:49h | UTCEndovascular Therapy for Acute Stroke with a Large Ischemic Region – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Endovascular Stroke Therapy Works for Large Infarcts: RESCUE-Japan LIMIT – TCTMD
AHA Scientific Statement: Identifying best practices to improve evaluation and management of in-hospital stroke.
10 Feb, 2022 | 10:13h | UTCNews Release: Five elements to optimize treatment of in-hospital stroke – American Heart Association
Commentary on Twitter
Identifying Best Practices to Improve Evaluation and Management of In-Hospital #Stroke: A Scientific Statement From the American Heart Association #AHAJournals #ISC22 https://t.co/e6zcLMeyBZ @American_Heart @AHAScience pic.twitter.com/eBgLc7OrBK
— Stroke AHA/ASA (@StrokeAHA_ASA) February 9, 2022
IDSA Updated Covid-19 Guideline now supports the use of convalescent plasma in ambulatory patients with mild to moderate COVID-19 at high risk for progression to severe disease.
9 Feb, 2022 | 10:15h | UTC
Commentary on Twitter
Update Alert: Revised recommendation on the use of #convalescentplasma in ambulatory patients w/ COVID-19 at high risk of progression to severe disease w/ no other treatment options.
📄: https://t.co/YRCxtdilXT#COVID19Guidelines @JGPharmD @adarsh_bhimraj @RMKGandhi @ShohamTxID pic.twitter.com/KpXnywH362
— IDSA (@IDSAInfo) February 8, 2022
European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.
9 Feb, 2022 | 10:18h | UTCRelated: IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.
The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022.
9 Feb, 2022 | 08:46h | UTC
Review: Supraventricular arrhythmia in pregnancy.
9 Feb, 2022 | 08:38h | UTCSupraventricular arrhythmia in pregnancy – Heart
Review | Prehospital plasma transfusion: what does the literature show?
9 Feb, 2022 | 08:22h | UTC
Review | Emergency blood transfusion for trauma and perioperative resuscitation.
9 Feb, 2022 | 08:22h | UTC
Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation.
7 Feb, 2022 | 08:56h | UTC
ERC-ESICM guidelines on temperature control after cardiac arrest in adults.
7 Feb, 2022 | 08:44h | UTCERC-ESICM guidelines on temperature control after cardiac arrest in adults – Intensive Care Medicine (if the link is paywalled, try this one)
Related:
Commentary on Twitter
Temperature control post ROSC @ERC_resus @ESICM guidelines:
🌡 monitor (core T) + prevent fever (min 72h)
❄️ insufficient evidence for/against 32-36°C or early cooling
Not recommended
🌡 active rewarming (mild hypothermia)
🚑 pre 🏥 cooling (cold fluids)https://t.co/w6X8fLInzf pic.twitter.com/U8TWG1oUyV— Intensive Care Medicine (@yourICM) January 28, 2022
M-A: Tranexamic acid in aneurysmal subarachnoid hemorrhage does not improve clinical outcomes or mortality.
7 Feb, 2022 | 08:26h | UTCEfficacy and safety of tranexamic acid in aneurysmal subarachnoid hemorrhage: A meta-analysis of randomized controlled trials – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
M-A: The effect of Dexmedetomidine as a sedative agent for mechanically ventilated patients with sepsis.
7 Feb, 2022 | 08:15h | UTC
Does my hospitalized patient need an NPO-after-midnight order preoperatively?
4 Feb, 2022 | 09:58h | UTCRelated:
Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.
Consensus Statement: Preoperative Management of Medications for Neurologic Diseases.
4 Feb, 2022 | 10:00h | UTCPreoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings
Related: Consensus Statement: Preoperative management of medications for psychiatric diseases.
Anaphylaxis: Highlights from the practice parameter update.
4 Feb, 2022 | 08:43h | UTCAnaphylaxis: Highlights from the practice parameter update – Cleveland Clinic Journal of Medicine
Podcast: Infective Endocarditis Pearls.
4 Feb, 2022 | 08:27h | UTCInfective Endocarditis Pearls – The Curbsiders
Thrombolytic use for STEMI: what ED clinicians should know.
4 Feb, 2022 | 08:23h | UTCThrombolytic Use for STEMI: What ED Clinicians Should Know – emDocs
Perspective: The origins, development, and context of the Lancet Commission on the Value of Death – “Death has turned from being a family, social, and cultural event to primarily a medical event”.
3 Feb, 2022 | 08:51h | UTCThe origins, development, and context of the Lancet Commission on the Value of Death – The BMJ
Cluster randomized controlled trial: An innovative telemedical network to improve infectious disease management in critically ill patients and outpatients.
3 Feb, 2022 | 08:53h | UTCRelated:
The “Choosing Wisely” initiative in infectious diseases – German Society of Infectious Diseases (link to abstract – $ for full-text)
Infectious Diseases Society of America: Five Things Physicians and Patients Should Question


