Critical Care & Emergencies (all articles)
Cohort Study: Characteristics and outcomes of Type 2 myocardial infarction.
18 Mar, 2022 | 08:05h | UTCCharacteristics and Outcomes of Type 2 Myocardial Infarction – JAMA Cardiology (link to abstract – $ for full-text)
Commentaries:
Type 2 MI Not Uncommon in the Emergency Department – TCTMD
Type 2 Myocardial Infarction: Clinical Characteristics and Outcomes – American College of Cardiology
Commentary on Twitter
Among patients presenting with acute chest discomfort to the emergency department, tachyarrhythmias and hypertension are responsible for more than two thirds of type 2 myocardial infarction and result in a lower mortality compared to other triggers. https://t.co/ODMCmOjeQO
— JAMA Cardiology (@JAMACardio) March 10, 2022
RCT: Oral contezolid vs. linezolid in adults with complicated skin and soft tissue infections.
18 Mar, 2022 | 07:54h | UTCA Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections – Journal of Antimicrobial Therapy (link to abstract – $ for full-text)
Commentary on Twitter
Phase III efficacy & safety of oral contezolid Vs linezolid in adults with c.SSTIs
📌Non inferior
📌Interestingly:Contezolid demonstrated significant lower incidence thrombocytopenia (0% Wow vs 2.3%) & leucopenia (0.3% vs 3.4%) than linezolid
📌QIDP https://t.co/wSvxUInnkZ— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) March 11, 2022
2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute sequelae of SARS-CoV-2 infection, and return to play.
17 Mar, 2022 | 09:26h | UTCCommentaries:
ACC Issues Clinical Guidance on CV Consequences of COVID-19 – American College of Cardiology
ACC Releases Guidance on CV Issues With COVID-19 – TCTMD
Key Points: 2022 ACC Decision Pathway on Cardiovascular Sequelae of COVID-19
Related:
Review | Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.
The pathogenesis and long-term consequences of Covid-19 cardiac injury: state-of-the-art review.
COVID-19 infections increase risk of heart conditions up to a year later, study finds.
Commentary on Twitter (thread – click for more)
Access the full ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-acute Sequelae of SARS-CoV-2 Infection, and Return to Play: https://t.co/ph75qZxfpT #JACC @JACCJournals #CardioTwitter (8/8) pic.twitter.com/mpYJic6gem
— American College of Cardiology (@ACCinTouch) March 16, 2022
Treatments for moderate to severe COVID-19: Cochrane evidence.
17 Mar, 2022 | 09:19h | UTCTreatments for moderate to severe COVID-19: Cochrane evidence – Evidently Cochrane
Treatments for mild COVID-19: Cochrane evidence.
17 Mar, 2022 | 09:17h | UTCTreatments for mild COVID-19: Cochrane evidence – Cochrane Library
Malignant Hypertension: Current perspectives and challenges.
17 Mar, 2022 | 09:03h | UTC
Open-Label, multicenter study of Flecainide Acetate oral inhalation solution for acute conversion of recent-onset, symptomatic atrial fibrillation to sinus rhythm.
17 Mar, 2022 | 09:01h | UTC
Commentary on Twitter
Inhalation of flecainide simply converts many episodes of recent onset atrial fibrillation #AHAJournals #HeartMonthhttps://t.co/vNXx4fKy2u pic.twitter.com/UNGA9DX3qM
— CircEP (@CirculationEP) February 25, 2022
M-A: The role of acute hypercapnia on mortality and short-term physiology in patients mechanically ventilated for ARDS.
17 Mar, 2022 | 08:31h | UTCThe role of acute hypercapnia on mortality and short-term physiology in patients mechanically ventilated for ARDS: a systematic review and meta-analysis – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
Acute hypercapnia in #ARDS pts on MV, SR/MA.
Conflicting effect! Protective effects of permissive hypercapnia seem driven by associated PV (improved hemodynamics) vs deleterious effects of imposed hypercapnia seem mediated by pulmonary vascular dysfunctionhttps://t.co/H1TuliectW pic.twitter.com/uLoAZPvbWg— Intensive Care Medicine (@yourICM) March 16, 2022
Happy TRALIdays: An overview of trauma resuscitation and transfusion complications.
17 Mar, 2022 | 08:08h | UTCHappy TRALIdays: An Overview of Trauma Resuscitation and Transfusion Complications – emDocs
Review: Role of imaging in rare COVID-19 vaccine multiorgan complications.
16 Mar, 2022 | 10:00h | UTCRole of imaging in rare COVID-19 vaccine multiorgan complications – Insights into Imaging
Electroencephalography in delirium assessment: a scoping review.
16 Mar, 2022 | 08:31h | UTCElectroencephalography in delirium assessment: a scoping review – BMC Neurology
Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists.
15 Mar, 2022 | 09:51h | UTC
Clinical practice guidelines for pain, agitation, delirium, immobility, and sleep disturbance in the intensive care unit.
15 Mar, 2022 | 08:45h | UTC
M-A: Similar outcomes with Beta-lactam monotherapy vs. combination therapy for bloodstream infections or pneumonia due to Pseudomonas aeruginosa.
15 Mar, 2022 | 08:29h | UTCBeta-lactam monotherapy or combination therapy for bloodstream infections or pneumonia due to Pseudomonas aeruginosa: a meta-analysis – International Journal of Antimicrobial Agents (link to abstract – $ for full-text)
Podcast: Cardiorenal Syndrome Pearls.
15 Mar, 2022 | 08:23h | UTC#326 NephMadness 2022: Cardiorenal Syndrome – The Curbsiders
Meta-analysis of randomized controlled trials comparing intraoperative red blood cell transfusion strategies.
14 Mar, 2022 | 01:47h | UTCRelated:
Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery
Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA
Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies.
14 Mar, 2022 | 01:04h | UTC
Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis.
14 Mar, 2022 | 01:14h | UTCRelated:
ERC-ESICM guidelines on temperature control after cardiac arrest in adults.
RCT: Effectiveness of Fosfomycin for treating multidrug-resistant Escherichia coli bacteremic urinary tract infections.
14 Mar, 2022 | 00:53h | UTCCommentaries:
The Role of Intravenous Fosfomycin: Finding Our Way Out of Dante’s Forest Dark – JAMA Network Open
Fosfomycin Not Noninferior to Comparators for Bacteremic UTI – HealthDay
‘Forgotten’ antibiotic recovered for resistant bacterial infections – University of Seville
Commentary on Twitter
In this RCT, fosfomycin did not demonstrate noninferiority in MDR-E coli bacteremic UTI, mostly due to adverse event-related withdrawals in mITT, but showed efficacy in per protocol analysis. #FORESTtrial @jesusrbano https://t.co/oiPtiQo2XA pic.twitter.com/Q44QQb18cN
— JAMA Network Open (@JAMANetworkOpen) January 13, 2022
Management of respiratory failure: ventilator management 101 and noninvasive ventilation.
14 Mar, 2022 | 00:45h | UTC
Review: Drug-induced acute kidney injury.
14 Mar, 2022 | 00:48h | UTCDrug-Induced Acute Kidney Injury – Clinical Journal of the American Society of Nephrology
RCT: Safety and efficacy of three enteral feeding strategies in patients with severe stroke.
11 Mar, 2022 | 09:51h | UTCSafety and efficacy of three enteral feeding strategies in patients with severe stroke in China (OPENS): a multicentre, prospective, randomised, open-label, blinded-endpoint trial – The Lancet Neurology (link to abstract – $ for full-text)
Efficacy and safety of non-operative management of uncomplicated acute appendicitis compared to appendectomy: an umbrella review of systematic reviews and meta-analyses.
11 Mar, 2022 | 09:49h | UTCRelated:
Review: Diagnosis of uncomplicated and complicated appendicitis in adults.
A Randomized trial comparing antibiotics with appendectomy for appendicitis
Association between statin use and daptomycin-related musculoskeletal adverse events: A mixed approach combining a meta-analysis and a disproportionality analysis.
11 Mar, 2022 | 09:39h | UTC
RCT: In patients with refractory out-of-hospital cardiac arrest, a strategy of intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and immediate invasive assessment did not significantly improve survival with a favorable neurological outcome (OR 1.63; 95% CI 0.93 to 2.85; P = .09).
10 Mar, 2022 | 10:57h | UTCEffect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Early Invasive Therapy for Out-of-Hospital Cardiac Arrest – American College of Cardiology
Commentary on Twitter
https://twitter.com/JAMA_current/status/1496183512025677829