Open access
Open access
Powered by Google Translator Translator

Critical Care & Emergencies (all articles)

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management.

11 Apr, 2022 | 02:00h | UTC

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management – American Journal of Emergency Medicine

 

Review: Atrial fibrillation.

11 Apr, 2022 | 01:57h | UTC

Atrial fibrillation – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Atrial fibrillation – Nature Reviews Disease Primers (if the link is paywalled, try this one)

 

Commentary on Twitter

 

RCT: Effect of Gram Stain–Guided initial antibiotic therapy on clinical response in patients with ventilator-associated pneumonia.

11 Apr, 2022 | 01:36h | UTC

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia: The GRACE-VAP Randomized Clinical Trial – JAMA Network Open

Commentary: Can Gram Stains Guide Antibiotics for Pneumonia in Critical Care? – Medscape (free registration required)

 

Commentary on Twitter

 

Clinical care of severe acute respiratory infections – Tool kit (COVID-19 adaptation, update 2022).

11 Apr, 2022 | 01:45h | UTC

Clinical care of severe acute respiratory infections – Tool kit – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

NCCN Guidelines: CAR T-cell–related toxicities in patients with cancer.

11 Apr, 2022 | 01:32h | UTC

Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Related:

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Critical Care Management of Chimeric Antigen Receptor T Cell–related Toxicity. Be Aware and Prepared

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

 

M-A: Oxygen targets during mechanical ventilation in the ICU.

11 Apr, 2022 | 01:26h | UTC

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

 

M-A: Prophylactic therapies for morbidity and mortality after aneurysmal subarachnoid hemorrhage.

11 Apr, 2022 | 00:52h | UTC

Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials – Stroke (link to abstract – $ for full-text)

Related: RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

 

Commentary on Twitter

 

M-A: Prehospital risk assessment in patients suspected of non-ST-segment elevation acute coronary syndrome.

11 Apr, 2022 | 00:48h | UTC

Prehospital risk assessment in patients suspected of non-ST-segment elevation acute coronary syndrome: a systematic review and meta-analysis – BMJ Open

 

Commentary on Twitter

 

RCT: In critically ill children requiring noninvasive respiratory support following extubation, high-flow nasal cannula therapy was NOT noninferior to CPAP, resulting in increased time to liberation from respiratory support.

8 Apr, 2022 | 11:07h | UTC

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (free for a limited period)

News Release: Trial identifies most effective breathing support for children in intensive care – Imperial College London

 

Commentary on Twitter

 

State of the Art Review: Prognostication and shared decision making in neurocritical care.

8 Apr, 2022 | 10:53h | UTC

Prognostication and shared decision making in neurocritical care – The BMJ

 

Commentary on Twitter

 

M-A: Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia.

8 Apr, 2022 | 10:50h | UTC

Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis – International Journal of Infectious Diseases

Related:

Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

Review: Vaccine-induced immune thrombotic thrombocytopenia.

Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance.

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)

 

M-A: Diagnostic performance of CO-RADS for Covid-19.

8 Apr, 2022 | 10:31h | UTC

Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis – European Radiology

Related: CO-RADS – A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation – Radiology

 

Stroke: advances in treatment offer hope for patients.

8 Apr, 2022 | 10:23h | UTC

Stroke: advances in treatment offer hope for patients – Evidently Cochrane

 

Study Commentary | Immediate versus delayed cardiac catheterization in post-arrest patients without ST elevation myocardial infarction: is survivorship bias an important influence?

8 Apr, 2022 | 10:11h | UTC

Immediate Versus Delayed Cardiac Catheterization in Post-Arrest Patients Without ST Elevation Myocardial Infarction: Is Survivorship Bias an Important Influence? – Annals of Emergency Medicine

Original Study: #ESCCongress – RCT: Immediate coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation did not improve outcomes compared to delayed/selective angiography.

 

Study Commentary | Back to BaSICS (study that compared balanced solution vs. 0.9% saline solution in critically ill patients).

8 Apr, 2022 | 10:09h | UTC

Back to BaSICS – Annals of Emergency Medicine

Original Studies:

BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.

BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.

Related:

Perspective: The ongoing saga of normal saline vs. balanced fluids.

RCT: In critically ill adults, using a balanced multielectrolyte solution did not lower the risk of death or acute kidney injury compared to standard saline.

Balanced Crystalloids versus Saline in Critically Ill Adults — A Systematic Review with Meta-Analysis – NEJM Evidence

Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline

 

Study Commentary | To Bougie or not to Bougie: Bougie vs. Stylet for first-pass intubation success.

8 Apr, 2022 | 10:07h | UTC

To Bougie or Not to Bougie: Bougie versus Stylet for First-Pass Intubation Success – Annals of Emergency Medicine

Original Study: RCT: In critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful first attempt intubation vs. with use of an endotracheal tube with stylet.

 

Brief Review: How to do lung ultrasound.

8 Apr, 2022 | 09:52h | UTC

How to do lung ultrasound – European Heart Journal – Cardiovascular Imaging

 

Study finds increased risk of pulmonary embolism up to 110 days after COVID-19.

7 Apr, 2022 | 10:06h | UTC

Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study – The BMJ

News Release: Study finds increased risk of serious blood clots up to six months after COVID-19 – BMJ

Editorial: Thromboembolism and bleeding after covid-19

Commentary: Covid: Blood clot risk higher for six months after having virus – BBC

 

Pragmatic RCT: In outpatients with Covid-19, the addition of pulse oximetry for monitoring did not improve outcomes compared to subjective assessments of dyspnea alone.

7 Apr, 2022 | 09:58h | UTC

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

 

Commentary on Twitter

 

RCT: Among patients with complicated urinary tract infection, oral Tebipenem Pivoxil Hydrobromide was noninferior to intravenous Ertapenem and showed a similar safety profile.

7 Apr, 2022 | 09:53h | UTC

Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

RCT: In patients undergoing intraarterial treatment for stroke, functional outcomes after 3 months were similar with general anesthesia vs. sedation.

7 Apr, 2022 | 08:00h | UTC

General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke: The GASS Randomized Trial – Anesthesia

 

Commentary on Twitter

 

Major burns: part 2. Anesthesia, intensive care and pain management.

7 Apr, 2022 | 07:59h | UTC

Major burns: part 2. Anaesthesia, intensive care and pain management – BJA Education

See also: Major burns: Part 1. Epidemiology, pathophysiology and initial management.

 

RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

6 Apr, 2022 | 10:47h | UTC

Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage: two randomized phase 3 trials in Japanese patients – Journal of Neurosurgery

 

Craniocervical artery dissections: a concise review for clinicians.

6 Apr, 2022 | 10:06h | UTC

Craniocervical Artery Dissections: A Concise Review for Clinicians – Mayo Clinic Proceedings

 

RCT: Erythropoietin not beneficial for patients with acute kidney injury.

6 Apr, 2022 | 10:02h | UTC

Erythropoietin in Acute Kidney Injury (EAKI): a pragmatic randomized clinical trial – BMC Nephrology

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.