RCT: In critically ill children requiring noninvasive respiratory support following extubation, high-flow nasal cannula therapy was NOT noninferior to CPAP, resulting in increased time to liberation from respiratory support.
8 Apr, 2022 | 11:07h | UTCEffect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (free for a limited period)
News Release: Trial identifies most effective breathing support for children in intensive care – Imperial College London
Commentary on Twitter
In this study, among critically ill children requiring noninvasive respiratory support following extubation, HFNC vs CPAP failed to meet the criterion for noninferiority for time to liberation from respiratory support. https://t.co/X1lNAO28le #CCR pic.twitter.com/XBnUpsqUNq
— JAMA (@JAMA_current) April 7, 2022