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Critical Care & Emergencies (all articles)

Brain death: a clinical overview.

27 Apr, 2022 | 07:48h | UTC

Brain death: a clinical overview – Journal of Intensive Care

 

Commentary on Twitter

 

Primary palliative care recommendations for critical care clinicians.

27 Apr, 2022 | 07:46h | UTC

Primary palliative care recommendations for critical care clinicians – Journal of Intensive Care

 

Review: Use of antimicrobials for bloodstream infections in the intensive care unit.

27 Apr, 2022 | 01:34h | UTC

Use of Antimicrobials for Bloodstream Infections in the Intensive Care Unit, a Clinically Oriented Review – Antibiotics

 

Practice Pointer: Making decisions about radiological imaging in pregnancy.

26 Apr, 2022 | 08:44h | UTC

Making decisions about radiological imaging in pregnancy – The BMJ

 

Yes, relapses after Paxlovid happen — now what?

26 Apr, 2022 | 08:18h | UTC

Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations

 

Commentary on Twitter

 

Cluster RCT: Supraglottic airway device vs. tracheal intubation in the initial airway management of out-of-hospital cardiac arrest.

26 Apr, 2022 | 08:12h | UTC

Supraglottic airway device versus tracheal intubation in the initial airway management of out-of-hospital cardiac arrest: the AIRWAYS-2 cluster RCT – Health Technology Assessment

Related Study: Effect of Placement of a Supraglottic Airway Device vs Endotracheal Intubation on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest in Taipei, Taiwan: A Cluster Randomized Clinical Trial – JAMA Network Open

 

Guideline: Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure.

26 Apr, 2022 | 08:03h | UTC

Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure –A clinical practice Guideline Level 3 – ESC Heart Failure

 

Podcast: Inpatient diabetes pearls.

26 Apr, 2022 | 07:48h | UTC

#330 Inpatient Diabetes with Dr. Dave Lieb – The Curbsiders

 

Gout in the ED: Pearls and pitfalls.

26 Apr, 2022 | 07:37h | UTC

Gout in the ED: Pearls and Pitfalls – emDocs

 

Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study.

25 Apr, 2022 | 01:00h | UTC

Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study (the ECHO-COVID study) – Intensive Care Medicine

 

Commentary on Twitter

 

WHO recommends highly successful COVID-19 therapy (nirmatrelvir-ritonavir) and calls for wide geographical distribution and transparency from originator.

22 Apr, 2022 | 09:36h | UTC

WHO recommends highly successful COVID-19 therapy and calls for wide geographical distribution and transparency from originator – World Health Organization

See also:

A living WHO guideline on drugs for covid-19 – The BMJ

Therapeutics and COVID-19: living guideline – World Health Organization

Related:

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

The COVID-19 Treatment Guidelines Panel’s Statement on Potential Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications – NIH COVID-19 Treatment Guidelines Panel

 

Commentary on Twitter

 

One-year follow-up of a RCT: In ICU patients with severe hypoxemia, there was no difference in long-term mortality and health-related quality of life with lower vs. higher oxygenation targets.

22 Apr, 2022 | 09:32h | UTC

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Original Study: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

 

Commentary on Twitter

 

Expert Guidance: Strategies to prevent central line-associated bloodstream infections in acute-care hospitals.

20 Apr, 2022 | 10:13h | UTC

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

 

Commentary on Twitter

Article under a http://creativecommons.org/licenses/by/4.0/ license

 

A nonrandomized controlled study found awake prone position (median of 4.2 hours per day) may not benefit hospitalized adults with Covid-19.

20 Apr, 2022 | 09:56h | UTC

Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial – JAMA Internal Medicine

Commentaries:

Prone Positioning for Nonintubated Patients With COVID-19—Potential Dangers of Extrapolation and Intermediate Outcome Variables – JAMA Internal Medicine

Study suggests worse outcomes for awake COVID patients in prone position – CIDRAP

Putting Hospitalized COVID Patients on Their Belly May Not Be a Good Idea After All – HealthDay

Related:

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv

Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial – Critical Care

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis – Critical Care Medicine

 

Commentary on Twitter (thread – click for more)

 

AAOS Guideline: Prevention of surgical site infections after major extremity trauma.

19 Apr, 2022 | 02:35h | UTC

Prevention of Surgical Site Infections After Major Extremity Trauma: Evidence-Based Clinical Practice Guideline – American Academy of Orthopaedic Surgeons

Evidence Review: Prevention of Surgical Site Infection After Extremity Trauma (2022)

 

Acute hepatitis in ED setting: etiologies, evaluation, and management.

19 Apr, 2022 | 01:54h | UTC

Acute Hepatitis in ED Setting: Etiologies, Evaluation, and Management – emDocs

 

Pre-transplant EASIX (endothelial activation and stress index) may predict the hazard of sepsis after allogeneic stem cell transplantation.

19 Apr, 2022 | 02:04h | UTC

Pre-transplant EASIX and sepsis after allogeneic stem cell transplantation – Intensive Care Medicine

 

Commentary on Twitter

 

Diarrhea during critical illness: a multicenter cohort study.

18 Apr, 2022 | 10:20h | UTC

Diarrhea during critical illness: a multicenter cohort study – Intensive Care Medicine

 

Commentary on Twitter

 

Guidelines for therapeutic drug monitoring of vancomycin in the framework of model-informed precision dosing.

18 Apr, 2022 | 10:26h | UTC

Clinical Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin in the Framework of Model-Informed Precision Dosing: A Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Pharmaceutics

Related Guideline:

Guideline: Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists – Clinical Infectious Diseases

 

Commentary on Twitter

https://twitter.com/IDPharmacometrx/status/1514219239732912131

 

Prospective validation of a rapid host gene expression test to discriminate bacterial from viral respiratory infection.

18 Apr, 2022 | 09:58h | UTC

Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection – JAMA Network Open

 

Commentary on Twitter

 

RCT: Comparison of intranasal vs. intramuscular naloxone in opioid overdoses managed by ambulance staff.

14 Apr, 2022 | 08:23h | UTC

Comparison of intranasal and intramuscular naloxone in opioid overdoses managed by ambulance staff: a double-dummy, randomised, controlled trial – Addiction

Commentary: Breathing restored within 10 minutes for 80% of overdose patients using nasal spray – Norwegian University of Science and Technology

 

Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis.

13 Apr, 2022 | 10:15h | UTC

Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis – Health Technology Assessment

 

Empyema: ED presentation, evaluation, and management.

12 Apr, 2022 | 08:44h | UTC

Empyema: ED Presentation, Evaluation, and Management – emDocs

 

Editorial | Who? When? Where? How? Still the alpha and omega of extracorporeal cardiopulmonary resuscitation.

12 Apr, 2022 | 08:49h | UTC

Who? When? Where? How? Still the alpha and omega of extracorporeal cardiopulmonary resuscitation – European Heart Journal. Acute Cardiovascular Care

Original Study: The association between time to extracorporeal cardiopulmonary resuscitation and outcome in patients with out-of-hospital cardiac arrest – European Heart Journal. Acute Cardiovascular Care (link to abstract – $ for full-text)

Related:

RCT: In patients with refractory out-of-hospital cardiac arrest, a strategy of intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and immediate invasive assessment did not significantly improve survival with a favorable neurological outcome (OR 1.63; 95% CI 0.93 to 2.85; P = .09).

Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications.

Guidelines for extracorporeal cardiopulmonary resuscitation in children and adults

 

Commentary on Twitter

 

Overview of diagnostic criteria and epidemiology of acute kidney injury and acute kidney disease in the critically ill patient.

12 Apr, 2022 | 08:30h | UTC

Overview of Diagnostic Criteria and Epidemiology of Acute Kidney Injury and Acute Kidney Disease in the Critically Ill Patient – Clinical Journal of the American Society of Nephrology

 

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