Emergency Medicine
Guidelines for the management of patients with severe acute pancreatitis.
21 Jun, 2022 | 10:57h | UTCRelated:
Evidence-Based Disposition of Acute Pancreatitis – emDocs
Pancreatitis – National Institute for Health and Care Excellence
Summary of the new 2022 AHA/ASA Guideline on intracerebral hemorrhage.
21 Jun, 2022 | 10:54h | UTCIntracerebral Hemorrhage 2022 Guideline Update – emDocs
Original Guideline: 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association – Stroke
Top Things to Know: 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage – American Heart Association
News Release: New guideline refines care for brain bleeds: compression socks, some meds not effective – American Heart Association
RCT: A restrictive intravenous fluid strategy does not improve outcomes in ICU patients with septic shock.
20 Jun, 2022 | 10:51h | UTCRestriction of Intravenous Fluid in ICU Patients with Septic Shock – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: No Fewer Deaths Seen With Restricted IV Fluid for Septic Shock – HealthDay
Related:
Fluid administration and monitoring in ARDS: which management? – Intensive Care Medicine
Commentary on Twitter
In this trial, a restrictive approach to intravenous fluid administration in critically ill patients with septic shock did not reduce mortality. #CCR22 https://t.co/UfY1936Qwb pic.twitter.com/FtSaDIIroj
— NEJM (@NEJM) June 17, 2022
[Preprint] Open-label RCT: Baricitinib noninferior to Tocilizumab in hospitalized patients with severe COVID-19.
20 Jun, 2022 | 10:28h | UTCRelated:
WHO recommends two new drugs to treat COVID-19 – World Health Organization
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 – New England Journal of Medicine
Commentary on Twitter
Preprint⚡⚡
Baricitinib Vs Tocilizumab open label RCT
Baricitinib was non-inferior to tocilizumab with regards to the composite outcome of mechanical ventilation or death by day 28 and the time to discharge by day 28 in patients with severe #COVID19 https://t.co/sQkhATkjEd— Antibiotic Steward Bassam Ghanem?? (@ABsteward) June 16, 2022
Brief Review: Helmet noninvasive support in hypoxemic respiratory failure.
20 Jun, 2022 | 01:13h | UTCHelmet noninvasive support in hypoxemic respiratory failure – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Helmet noninvasive support in hypoxemic respiratory failure:
⚙️ set‐up
⛑ physiology of helmet interface: from most relevant feature to major drawbacks
? clinical implications
Free to read #FOAMcc on @yourICM
? https://t.co/qNE4Id5oBg pic.twitter.com/b2auLLlW9z— Intensive Care Medicine (@yourICM) June 18, 2022
RCT: Immune enhancement with Thymosin alpha 1 does not improve outcomes in patients with predicted severe acute necrotizing pancreatitis.
20 Jun, 2022 | 01:11h | UTCImmune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial – Intensive Care Medicine (if the link is paywalled, try this one)
Registry-based cohort study: Endovascular treatment vs. best medical management in acute basilar artery occlusion strokes.
17 Jun, 2022 | 11:03h | UTCEndovascular Treatment Versus Best Medical Management in Acute Basilar Artery Occlusion Strokes: Results From the ATTENTION Multicenter Registry – Circulation (free for a limited period)
Commentary on Twitter
#ResearchLetter In 2134 patients with basilar artery occlusion #stroke, endovascular treatment was associated with improved functional capacity. The effect was more pronounced in patients with more debilitating symptoms #AHAJournals https://t.co/wy4uFocYlR pic.twitter.com/TIBRVAXRhE
— Circulation (@CircAHA) June 10, 2022
#CCR22 – RCT: Among critically ill patients undergoing tracheal intubation, administering a 500 ml fluid bolus did not decrease the incidence of severely low blood pressure, cardiac arrest, or death.
16 Jun, 2022 | 11:08h | UTCEffect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
In this randomized clinical trial, among critically ill adults undergoing tracheal intubation, administration of a fluid bolus did not significantly decrease the incidence of cardiovascular collapse. https://t.co/vPkfgLBF1n #CCR22
— JAMA (@JAMA_current) June 16, 2022
Review: The physiological underpinnings of life-saving respiratory support.
16 Jun, 2022 | 11:03h | UTCThe physiological underpinnings of life-saving respiratory support – Intensive Care Medicine
Commentary on Twitter
Physiology of life-saving respiratory support:
➡️historical overview
➡️pathophysiology of respiratory failure
Invasive mechanical ventilation & extracorporeal support #ECLS #ECMO:
➡️rationale
➡️implementation
➡️iatrogenic consequences
➡️future#FOAMcc
? https://t.co/EEvfpqVKIa pic.twitter.com/4t7wl53Jpz— Intensive Care Medicine (@yourICM) June 12, 2022
Interventions in acute intracranial surgery: an evidence-based perspective.
16 Jun, 2022 | 10:59h | UTCInterventions in Acute Intracranial Surgery: An Evidence-Based Perspective – World Neurosurgery
M-A: Acute or subacute, the optimal timing for uncomplicated Type B aortic dissection.
16 Jun, 2022 | 10:46h | UTC
AHA Scientific Statement: Toward a better understanding of sex- and gender-related differences in endovascular stroke treatment.
15 Jun, 2022 | 11:26h | UTCNews Release: More data needed on stroke treatment and outcomes by sex, gender – American Heart Association
Commentary on Twitter
Toward a Better Understanding of Sex- and Gender-Related Differences in Endovascular Stroke Treatment: A Scientific Statement From the American Heart Association/American Stroke Associationhttps://t.co/oXrdiLZfNK pic.twitter.com/Z4kMZG4Ymm
— Collavidence (@collavidence) June 13, 2022
Review: Sepsis management for the nephrologist.
15 Jun, 2022 | 11:23h | UTCSepsis Management for the Nephrologist – Clinical Journal of the American Society of Nephrology
Encephalopathy in cirrhosis: prevention and management.
15 Jun, 2022 | 10:39h | UTC
Review: Portal vein thrombosis in cirrhosis.
15 Jun, 2022 | 10:38h | UTCPortal Vein Thrombosis in Cirrhosis – Journal of Clinical and Experimental Hepatology
Cohort Study | Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration.
15 Jun, 2022 | 10:34h | UTC
Study Commentary: Dexamethasone should not be given to people with a chronic subdural hematoma.
15 Jun, 2022 | 10:28h | UTCDexamethasone should not be given to people with a chronic subdural haematoma
Original Study: Trial of Dexamethasone for Chronic Subdural Hematoma – New England Journal of Medicine
Guideline: Management of hyperglycemia in hospitalized adult patients in non-critical care settings.
14 Jun, 2022 | 11:22h | UTCCommentary: Endocrine Society Issues New Guidelines for Hospitalized Patients With Diabetes – Clinical Advisor
Related:
Podcast: #330 Inpatient Diabetes with Dr. Dave Lieb – The Curbsiders
Review: Managing hyperglycaemia in inpatients – Clinical Medicine Journal
Systematic Review: Janus kinase inhibitors for the treatment of COVID‐19.
14 Jun, 2022 | 11:14h | UTCJanus kinase inhibitors for the treatment of COVID‐19 – Cochrane Library
Review | Body packers, stuffers, and pushers: time bombs in our Eds.
14 Jun, 2022 | 10:50h | UTCBody Packers, Stuffers, and Pushers: Time Bombs in Our Eds – emDocs
BSH guideline for the hematological management of major hemorrhage.
13 Jun, 2022 | 10:53h | UTC
M-A: Respiratory viral co-infections in patients with COVID-19 and associated outcomes.
13 Jun, 2022 | 10:41h | UTC
NIH Updated Guideline: Oxygenation and ventilation for adults with Covid-19.
13 Jun, 2022 | 10:44h | UTCOxygenation and Ventilation for Adults – National Institutes of Health
RCT: Emergency vs. delayed coronary angiogram in survivors of out-of-hospital cardiac arrest.
13 Jun, 2022 | 10:42h | UTCEmergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial – JAMA Cardiology (free for a limited period)
Commentary on Twitter
In this RCT, performing an emergency coronary angiogram (CAG) after an out-of-hospital cardiac arrest without ST-segment elevation showed no difference in the 180-day survival rate compared to a delayed CAG. https://t.co/gYwPdNV32v
— JAMA Cardiology (@JAMACardio) June 8, 2022
Long-term follow-up of RCT: Decompressive craniectomy vs. standard medical care in patients with traumatic intracranial hypertension.
10 Jun, 2022 | 12:45h | UTCEvaluation of Outcomes Among Patients With Traumatic Intracranial Hypertension Treated With Decompressive Craniectomy vs Standard Medical Care at 24 Months: A Secondary Analysis of the RESCUEicp Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Original Study: Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension – New England Journal of Medicine
Related:
The Current Status of Decompressive Craniectomy in Traumatic Brain Injury – Current Trauma Reports
Commentary on Twitter
In this study, at 24 months, patients with posttraumatic refractory intracranial hypertension managed with a decompressive craniectomy had a sustained mortality reduction and higher rates of vegetative state, severe disability, and moderate disability. https://t.co/I8GqG885jh
— JAMA Neurology (@JAMANeuro) June 9, 2022