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Emergency Medicine

Review | Management of liver decompensation in advanced chronic liver disease: ascites, hyponatremia, and gastroesophageal variceal bleeding.

4 Aug, 2022 | 13:40h | UTC

Management of Liver Decompensation in Advanced Chronic Liver Disease: Ascites, Hyponatremia, and Gastroesophageal Variceal Bleeding – Clinical Drug Investigation

Related: Overview of Complications in Cirrhosis – Journal of Clinical and Experimental Hepatology

 


Review | Management of liver decompensation in advanced liver disease (renal impairment, liver failure, adrenal insufficiency, cardiopulmonary complications).

2 Aug, 2022 | 11:48h | UTC

Management of Liver Decompensation in Advanced Liver Disease (Renal Impairment, Liver Failure, Adrenal Insufficiency, Cardiopulmonary Complications) – Clinical Drug Investigation

 


Review | Cutaneous manifestations of acute kidney injury.

2 Aug, 2022 | 11:46h | UTC

Cutaneous manifestations of acute kidney injury – Clinical Kidney Journal

 


Review | Sciatica mimics.

2 Aug, 2022 | 11:54h | UTC

Sciatica Mimics – emDocs

 


Review | Treatment of acute kidney injury in cancer patients.

2 Aug, 2022 | 11:43h | UTC

Treatment of acute kidney injury in cancer patients – Clinical Kidney Journal

Related:

Onconephrology: Update in Anticancer Drug-Related Nephrotoxicity – Nephron

Acute Kidney Injury in Critically Ill Patients with Cancer – Clinical Journal of the American Society of Nephrology

Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents – Kidney Research and Clinical Practice

KDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer – Kidney International

 


M-A | Respiratory support strategy in adults with acute hypoxemic respiratory failure.

1 Aug, 2022 | 12:18h | UTC

Respiratory support strategy in adults with acute hypoxemic respiratory failure: a systematic review and network meta-analysis – JA Clinical Reports

 


Cohort Study | Analysis of prescriptions for dual antiplatelet therapy after acute ischemic stroke.

29 Jul, 2022 | 12:20h | UTC

Analysis of Prescriptions for Dual Antiplatelet Therapy After Acute Ischemic Stroke – JAMA Network Open

Related:

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

Multiple versus fewer antiplatelet agents for preventing early recurrence after ischaemic stroke or transient ischaemic attack – Cochrane Library

2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association – Stroke

Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence

Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials – Stroke

Efficacy and Safety of Using Dual Versus Monotherapy Antiplatelet Agents in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials – Circulation

 

Commentary on Twitter

 


M-A | Antiviral drug treatment for nonsevere COVID-19.

27 Jul, 2022 | 12:14h | UTC

Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis – Canadian Medical Association Journal

News Release: Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths – Canadian Medical Association Journal

Commentary: COVID-19 antivirals may cut risk of hospitalization, death – CIDRAP

 


M-A | Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19.

27 Jul, 2022 | 12:12h | UTC

Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19: a systematic review and meta-analysis of randomized controlled trials – American Journal of Medicine

 


NICE Guideline | Pneumonia in adults: diagnosis and management.

26 Jul, 2022 | 13:37h | UTC

Pneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence

Related Guidelines:

Pneumonia (community-acquired): antimicrobial prescribing

Pneumonia (hospital-acquired): antimicrobial prescribing

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical Care Medicine

 


Single-center RCT | A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis.

22 Jul, 2022 | 11:40h | UTC

A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis (PROCAP): a single-centre, patient-blinded, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Retrospective cohort study | Impact of ethnicity on the accuracy of measurements of oxygen saturations.

21 Jul, 2022 | 13:15h | UTC

Impact of ethnicity on the accuracy of measurements of oxygen saturations: A retrospective observational cohort study – eClinicalMedicine

Related:

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 


Review | Therapeutic advances in alcohol-associated hepatitis.

21 Jul, 2022 | 12:36h | UTC

Therapeutic advances in alcohol-associated hepatitis – Journal of Hepatology

Related: Liver Transplantation in Alcohol-related Liver Disease and Alcohol-related Hepatitis – Journal of Clinical and Experimental Hepatology

 

Commentary on Twitter

 


High-sensitivity cardiac troponin and the 2021 AHA/ACC Guidelines for the evaluation and diagnosis of acute chest pain.

20 Jul, 2022 | 12:29h | UTC

High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain – Circulation (free for a limited period)

Summary: High-Sensitivity Cardiac Troponin and the 2021 Guidelines for Acute Chest Pain – American College of Cardiology

 

Commentary on Twitter

 


Podcast | Life-threatening conditions during pregnancy.

19 Jul, 2022 | 13:42h | UTC

Life-threatening Conditions During Pregnancy – JAMA

 


EASL Clinical Practice Guidelines on the management of hepatic encephalopathy.

18 Jul, 2022 | 11:49h | UTC

EASL Clinical Practice Guidelines on the management of hepatic encephalopathy – Journal of Hepatology

 

Commentary on Twitter

 


RCT | Tixagevimab-cilgavimab for treatment of patients hospitalized with COVID-19.

15 Jul, 2022 | 13:02h | UTC

Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial – The Lancet Respiratory Medicine

Commentary: The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients – News Medical

Related:

Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Respiratory Medicine

Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19 – New England Journal of Medicine

 

Commentary on Twitter

 


M-A (mostly of observational studies) | Catheter-directed thrombolysis vs. systemic anticoagulation alone for submassive pulmonary embolism.

15 Jul, 2022 | 12:39h | UTC

Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism – American Journal of Cardiology

 


RCT | Endovascular thrombectomy NOT noninferior to standard bridging thrombolytic with endovascular thrombectomy within 4.5 h of stroke onset.

13 Jul, 2022 | 11:57h | UTC

Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)

Related Study: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 


RCT | Thrombectomy alone NOT noninferior to intravenous alteplase plus thrombectomy in patients with stroke.

13 Jul, 2022 | 11:55h | UTC

Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)

Related Study: Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses.

13 Jul, 2022 | 11:51h | UTC

Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses – The BMJ

 


Navigating a Complicated World | Commentary of the new AHA/ACC Chest Pain Guidelines.

12 Jul, 2022 | 12:40h | UTC

Navigating a Complicated World: The American Heart Association/American College of Cardiology/American College of Chest Physicians/Society of Academic Emergency Medicine/Society of Cardiovascular Computed Tomography/Society of Cardiovascular Magnetic Resonance Chest Pain Guidelines – CHEST

Original Guideline: 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain

Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD

 


Cochrane review on endovascular thrombectomy and intra-arterial interventions for acute ischemic stroke.

12 Jul, 2022 | 12:29h | UTC

Cochrane Review on Endovascular Thrombectomy and Intra-Arterial Interventions for Acute Ischemic Stroke – Stroke (free for a limited period)

 


Review | How to evaluate and care for the suicidal patient in the emergency department.

12 Jul, 2022 | 11:55h | UTC

How to evaluate and care for the suicidal patient in the ED – emDocs

 


Hypertensive disorders in pregnancy complicated by liver rupture or hematoma: a systematic review of 391 reported cases.

12 Jul, 2022 | 11:48h | UTC

Hypertensive disorders in pregnancy complicated by liver rupture or hematoma: a systematic review of 391 reported cases – World Journal of Emergency Surgery

 


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