Open access
Open access
Powered by Google Translator Translator

Critical Care

RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.

23 Aug, 2021 | 00:03h | UTC

Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine

Invited commentary: Awake prone positioning in COVID-19: is tummy time ready for prime time?

Related:

RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.

M-A: Prone positioning of nonintubated patients with Covid-19 improve oxygenation variables without any reported serious adverse events – randomized trials with patient-relevant outcomes such as the need for intubation or mortality rates are required

 

Commentary on Twitter

 

Study Commentaries: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial.

22 Aug, 2021 | 23:52h | UTC

Commentary 1: JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial – St Emlyn’s

Commentary 2: An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19 – The Bottom Line

Original study: [Preprint] RCT: non-invasive respiratory strategies in acute respiratory failure in patients with COVID-19 – CPAP reduced the composite outcome of intubation or death within 30 days; high-flow nasal oxygenation was not associated with better outcomes.

 

M-A of randomized trials: The effect of higher versus lower protein delivery in critically ill patients – “In critically ill patients, a higher daily protein delivery was not associated with any improvement in clinical or patient-centered outcomes”.

20 Aug, 2021 | 08:57h | UTC

The effect of higher versus lower protein delivery in critically ill patients: a systematic review and meta-analysis of randomized controlled trials – Critical Care

 

Variations in end-of-life practices in intensive care units worldwide: a prospective observational study.

20 Aug, 2021 | 08:51h | UTC

Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection.

20 Aug, 2021 | 08:41h | UTC

Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection – JAC-Antimicrobial Resistance

 

Review: Viral respiratory pathogens and lung injury.

20 Aug, 2021 | 08:43h | UTC

Viral Respiratory Pathogens and Lung Injury – Clinical Microbiology Reviews

 

Viewpoint: Confronting the Delta variant of SARS-CoV-2.

19 Aug, 2021 | 09:03h | UTC

Confronting the Delta Variant of SARS-CoV-2, Summer 2021 – JAMA

 

NIH study shows no significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms.

19 Aug, 2021 | 09:06h | UTC

NIH study shows no significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms – NIH News Releases

Original study: Early Convalescent Plasma for High-Risk Outpatients with Covid-19 – New England Journal of Medicine

 

Commentary on Twitter

 

Hemophagocytic lymphohistiocytosis secondary to COVID-19: a case series.

19 Aug, 2021 | 08:57h | UTC

Haemophagocytic lymphohistiocytosis secondary to COVID-19: a case series – The Lancet Rheumatology

 

Delirium in critical illness: clinical manifestations, outcomes, and management.

18 Aug, 2021 | 08:47h | UTC

Delirium in critical illness: clinical manifestations, outcomes, and management – Intensive Care Medicine (if this link does not work, try this one)

Related:

M-A: Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients.

ICU Survivorship—The relationship of delirium, sedation, dementia, and acquired weakness.

Systematic review: In hospitalized non‐ICU patients, multicomponent non-pharmacological interventions are estimated to reduce the incidence of delirium by 43% compared to usual care.

 

Commentary on Twitter

 

Systematic review: Systemic corticosteroids for the treatment of COVID‐19.

17 Aug, 2021 | 09:11h | UTC

Systemic corticosteroids for the treatment of COVID‐19 – Cochrane Library

Summary: Are corticosteroids given orally or by injection an effective treatment for people with COVID-19? – Cochrane Library

 

Commentary on Twitter (thread – click for more)

 

Top antimicrobial stewardship intervention publications in 2020.

17 Aug, 2021 | 08:51h | UTC

A Baker’s Dozen of Top Antimicrobial Stewardship Intervention Publications in 2020 – Open Forum Infectious Diseases

 

P/FP ratio: incorporation of PEEP into the PaO2/FiO2 ratio for prognostication and classification of acute respiratory distress syndrome.

17 Aug, 2021 | 08:46h | UTC

P/FP ratio: incorporation of PEEP into the PaO2/FiO2 ratio for prognostication and classification of acute respiratory distress syndrome – Annals of Intensive Care

 

Commentary on Twitter

 

Cohort study: Early invasive coronary angiography in patients with acute ischemic heart failure is linked to better outcomes.

17 Aug, 2021 | 08:44h | UTC

Early invasive coronary angiography and acute ischaemic heart failure outcomes – European Heart Journal

Commentary: Early Invasive Angiography in Acute Heart Failure – American College of Cardiology

 

Commentary on Twitter

 

Review: Initial management of blunt and penetrating neck trauma.

17 Aug, 2021 | 08:40h | UTC

Initial management of blunt and penetrating neck trauma – BJA Education

 

Guideline: Acute abdomen in the immunocompromised patient.

16 Aug, 2021 | 01:00h | UTC

Acute abdomen in the immunocompromised patient: WSES, SIS-E, WSIS, AAST, and GAIS guidelines – World Journal of Emergency Surgery

 

M-A: Targeted temperature management following out-of-hospital cardiac arrest – “Routine use of moderate or deep hypothermia in comatose survivors of OHCA may potentially be associated with more harm than benefit”.

16 Aug, 2021 | 00:55h | UTC

Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets – Intensive Care Medicine (free for a limited period)

Related: RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

 

Commentary on Twitter

 

Expert analysis: PCI for Multivessel Disease in STEMI.

16 Aug, 2021 | 00:49h | UTC

PCI for Multivessel Disease in STEMI – American College of Cardiology

 

Commentaries on Twitter

 

How COVID-19 will change the management of other respiratory viral infections.

13 Aug, 2021 | 09:52h | UTC

How COVID-19 will change the management of other respiratory viral infections – Intensive Care Medicine

 

Commentary on Twitter

 

M-A: Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients.

13 Aug, 2021 | 09:01h | UTC

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis – Intensive Care Medicine

 

Commentary on Twitter

 

Review: Oxygenation strategies after extubation of critically ill and postoperative patients.

13 Aug, 2021 | 08:49h | UTC

Oxygenation strategies after extubation of critically ill and postoperative patients – Journal of Intensive Medicine

 

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

12 Aug, 2021 | 09:05h | UTC

Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis – New England Journal of Medicine

Commentary: Largest Study of VITT After COVID-19 Vaccination Digs Into Lab, Clinical Features – TCTMD

Related:

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)

 

Commentary on Twitter

 

2021 guidelines for management of venous thromboembolism in Latin America.

12 Aug, 2021 | 08:56h | UTC

ASH, ABHH, ACHO, Grupo CAHT, Grupo  CLAHT, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Sociedad Panameña de Hematología, SPH, and SVH 2021 guidelines for management of venous thromboembolism in Latin America – Blood Advances

 

BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.

11 Aug, 2021 | 08:37h | UTC

Effect of Slower vs Faster Intravenous Fluid Bolus Rates on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Does Crystalloid Composition or Rate of Fluid Administration Make a Difference When Resuscitating Patients in the ICU? – JAMA (free for a limited period)

Video: Balanced Solution vs. Saline in Intensive Care Study

 

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

11 Aug, 2021 | 08:44h | UTC

Clinical Characteristics and Pharmacological Management of COVID-19 Vaccine–Induced Immune Thrombotic Thrombocytopenia With Cerebral Venous Sinus Thrombosis: A Review – JAMA Cardiology

Related:

NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)

 

Commentary on Twitter

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.