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Critical Care

RCT: Early computed tomography coronary angiography in patients with suspected acute coronary syndrome did not improve one year clinical outcomes.

3 Oct, 2021 | 22:35h | UTC

Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial – The BMJ

 

Commentary on Twitter

 


Oral health care for the critically ill: a narrative review.

3 Oct, 2021 | 22:25h | UTC

Oral health care for the critically ill: a narrative review – Critical Care

 


International registry shows mortality after ECMO for patients with COVID-19 worsened during 2020.

1 Oct, 2021 | 10:43h | UTC

Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry – The Lancet

Commentaries:

ECMO in COVID-19: do not blame the tool – The Lancet

ECMO life support offers sickest COVID-19 patients a chance to survive, but a slimmer one than once thought – Michigan Medicine – University of Michigan

 

Commentary on Twitter (thread – click for more)

 


Another meta-analysis suggests standard-dose prophylactic anticoagulation is the best option for patients hospitalized with Covid-19.

1 Oct, 2021 | 10:35h | UTC

A Systematic Review and a Meta-Analysis Comparing Prophylactic and Therapeutic Low Molecular Weight Heparins for Mortality Reduction in 32,688 COVID-19 Patients – Frontiers in Pharmacology

Related: M-A: Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19 – According to this analysis, standard-dose prophylactic anticoagulation should be the standard of care for hospitalized patients with COVID-19 who do not have an indication for therapeutic anticoagulation, irrespective of disease severity.

 


WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections.

1 Oct, 2021 | 10:24h | UTC

WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections – World Journal of Emergency Surgery

Related:

The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections

The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections – World Journal of Emergency Surgery

 


Fire safety and emergency evacuation guidelines for intensive care units and operating theatres: for use in the event of fire, flood, power cut, oxygen supply failure, noxious gas, structural collapse or other critical incidents.

1 Oct, 2021 | 10:15h | UTC

Fire safety and emergency evacuation guidelines for intensive care units and operating theatres: for use in the event of fire, flood, power cut, oxygen supply failure, noxious gas, structural collapse or other critical incidents – Anaesthesia

 


Cardiac troponin and defining myocardial infarction.

1 Oct, 2021 | 10:11h | UTC

Cardiac troponin and defining myocardial infarction – Cardiovascular Research

 


RCT: REGEN-COV antibody combination reduces hospitalizations in outpatients with Covid-19.

30 Sep, 2021 | 10:33h | UTC

REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19 – New England Journal of Medicine

 


Review: Clinical features, laboratory, and radiological findings of patients with acute inflammatory myelopathy after COVID-19 infection.

30 Sep, 2021 | 10:27h | UTC

Clinical Features, Laboratory, and Radiological Findings of Patients With Acute Inflammatory Myelopathy After COVID-19 Infection: A Narrative Review – American Journal of Physical Medicine & Rehabilitation

 


RCT: Vasopressin + Methylprednisolone increase the likelihood of return of spontaneous circulation compared to placebo in patients with in-hospital cardiac arrest.

30 Sep, 2021 | 10:23h | UTC

Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Vasopressin and Steroids as Adjunctive Treatment for In-Hospital Cardiac Arrest (free for a limited period)

 

Commentary on Twitter

 


Supplement: Acute Respiratory Distress Syndrome.

30 Sep, 2021 | 10:03h | UTC

Homepage: Acute Respiratory Distress Syndrome – Critical Care Clinics

The Epidemiology of Acute Respiratory Distress Syndrome Before and After Coronavirus Disease 2019

Toward Optimal Acute Respiratory Distress Syndrome Outcomes

Pathophysiology of Acute Respiratory Distress Syndrome and COVID-19 Lung Injury

COVID-19–Associated Acute Respiratory Distress Syndrome

Pathophysiology of the Acute Respiratory Distress Syndrome

Acute Kidney Injury and Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

Fluid Therapy and Acute Respiratory Distress Syndrome

Pharmacologic Treatments for Acute Respiratory Distress Syndrome

Long-Term Outcomes in Acute Respiratory Distress Syndrome

Related:

Position paper: Advancing precision medicine for acute respiratory distress syndrome.

Review: Personalized mechanical ventilation in acute respiratory distress syndrome.

Seminar | Acute respiratory distress syndrome.

M-A of randomized trials: In patients with acute respiratory distress syndrome, there was no difference in mortality between higher vs. lower positive end-expiratory pressure strategies.

M-A: High versus low PEEP levels for mechanically ventilated adult patients with acute lung injury and ARDS

M-A: Decreased mortality in acute respiratory distress syndrome patients treated with corticosteroids

ARDS: Contemporary management and novel approaches during COVID-19

Systematic review: Evidence-based practices for acute respiratory failure and Acute Respiratory Distress Syndrome

Current and evolving standards of care for patients with acute respiratory distress syndrome (ARDS). Definition, ventilatory support, fluid management, use of corticosteroids, indications of prone positioning and ECMO, and more.

 


EM Cases: Liver Emergencies – Acute liver failure, hepatic encephalopathy, hepatorenal syndrome, liver test interpretation & drugs to avoid.

30 Sep, 2021 | 10:04h | UTC

EM Cases: Liver Emergencies – Acute Liver Failure, Hepatic Encephalopathy, Hepatorenal Syndrome, Liver Test Interpretation & Drugs to Avoid – emDocs

 


M-A: Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID-19 patients.

29 Sep, 2021 | 10:24h | UTC

Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID-19 patients: A systematic review and meta-analysis – Reviews in Medical Virology

 


AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis.

29 Sep, 2021 | 10:07h | UTC

AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis – Gastroenterology

See also: AGA Technical Review on Coagulation in Cirrhosis – Gastroenterology

 


Review: Life-threatening skin conditions presenting to critical care.

28 Sep, 2021 | 08:57h | UTC

Life-threatening skin conditions presenting to critical care – BJA Education

 


Podcast: Neutropenic Fever.

28 Sep, 2021 | 08:52h | UTC

#288 LIVE! Neutropenic Fever featuring Dr. Susan Seo – The Curbsiders

 


Updated WHO Living Guideline: Therapeutics and COVID-19.

26 Sep, 2021 | 22:16h | UTC

Therapeutics and COVID-19: living guideline – World Health Organization

WHO Statement: On new recommendation for treatment of COVID-19 patients: WHO calls for equitable access to casirivimab and imdevimab for COVID-19

See also:

WHO recommends antibody treatment for COVID patients at high risk of hospital admission.

Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis – The BMJ

Commentary: WHO adds new recommendation for COVID-19 monoclonal antibody combo – CIDRAP

 


WHO recommends antibody treatment for COVID patients at high risk of hospital admission.

24 Sep, 2021 | 10:11h | UTC

WHO recommends antibody treatment for COVID patients at high risk of hospital admission – British Medical Journal

Original article and infographic: A living WHO guideline on drugs for covid-19 – The BMJ

 


Review: Focused management of patients with severe acute brain injury and ARDS.

24 Sep, 2021 | 08:52h | UTC

Focused Management of Patients with Severe Acute Brain Injury and ARDS – CHEST

 


Systematic review: Clinical characteristics of multisystem inflammatory syndrome in adults.

23 Sep, 2021 | 10:12h | UTC

Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults: A Systematic Review – JAMA Network Open

 

Commentary on Twitter

 


Vasopressor-Sparing Strategies in Patients with Shock: A Scoping-Review and an Evidence-Based Strategy Proposition.

23 Sep, 2021 | 09:51h | UTC

Vasopressor-Sparing Strategies in Patients with Shock: A Scoping-Review and an Evidence-Based Strategy Proposition – Journal of Clinical Medicine

 


Phenotypes and subphenotypes of delirium: a review of current categorizations and suggestions for progression.

23 Sep, 2021 | 09:54h | UTC

Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression – Critical Care

 


Consensus Conference: Critically ill cancer patient’s resuscitation.

22 Sep, 2021 | 10:16h | UTC

Critically ill cancer patient’s resuscitation: a Belgian/French societies’ consensus conference – Intensive Care Medicine

 

Commentary on Twitter

 


Essential Emergency and Critical Care: A consensus among global clinical experts.

22 Sep, 2021 | 10:07h | UTC

Essential Emergency and Critical Care: a consensus among global clinical experts – BMJ Global Health

News releases:

40 steps to reduce deaths from critical illness – London School of Hygiene & Tropical Medicine

40 simple steps to reduce deaths from critical illness – Karolisnka Institutet

 

Commentary on Twitter

 


RCT: Probiotics do not reduce the incidence of ventilator-associated pneumonia in critically ill patients.

22 Sep, 2021 | 10:03h | UTC

Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: Probiotic Flops for Ventilator-Associated Pneumonia Prevention – MedPage Today (free registration required)

 


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