All Posts | Links Medicus - Free Medical News & Perspective

Review | Comprehensive care of women with genetic predisposition to breast and ovarian cancer

5 Apr, 2023 | 13:32h | UTC

Comprehensive Care of Women With Genetic Predisposition to Breast and Ovarian Cancer – Mayo Clinic Proceedings

Review | Why is intradialytic hypotension the commonest complication of outpatient dialysis treatments?

5 Apr, 2023 | 13:28h | UTC

Why is Intradialytic Hypotension the Commonest Complication of Outpatient Dialysis Treatments? – Kidney International Reports

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019

5 Apr, 2023 | 13:27h | UTC

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global Burden of Disease Study 2019 – BMJ Open

Adolescent sudden cardiac death: the role of underlying conditions and physical activity

5 Apr, 2023 | 13:26h | UTC

Sudden Cardiac Death Among Adolescents in the United Kingdom – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary on Twitter

Among the causes of SCD in adolescents, arrhythmogenic #cardiomyopathy, coronary artery anomalies & commotio cordis are more common in young athletes who die suddenly than in similarly aged sedentary individuals.

Read more on this https://t.co/VHRIiNz1hE… pic.twitter.com/N3bev3Nv8i

— JACC Journals (@JACCJournals) March 14, 2023

Updated ADAURA trial results | Adjuvant Osimertinib improves disease-free survival in resected EGFR-mutated NSCLC

5 Apr, 2023 | 13:21h | UTC

Adjuvant Osimertinib for Resected EGFR-Mutated Stage IB-IIIA Non–Small-Cell Lung Cancer: Updated Results From the Phase III Randomized ADAURA Trial – Journal of Clinical Oncology

News Release: Trial Shows Significant Disease-free Survival for Patients Diagnosed With Non-small Cell Lung Cancer – Yale School of Medicine

M-A | Vaginal swab outperforms urine for detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis

5 Apr, 2023 | 13:23h | UTC

Vaginal Swab vs Urine for Detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis: A Meta-Analysis – Annals of Family Medicine

M-A | The efficacy of topical prostaglandin analogs for hair loss

5 Apr, 2023 | 13:20h | UTC

The efficacy of topical prostaglandin analogs for hair loss: A systematic review and meta-analysis – Frontiers in Medicine

SR | The effectiveness of the interventions to reduce sound levels in the ICU

5 Apr, 2023 | 13:19h | UTC

The Effectiveness of the Interventions to Reduce Sound Levels in the ICU: A Systematic Review – Critical Care Explorations

Hydroxyurea use in youths with sickle cell anemia: underused despite updated 2014 guidelines

5 Apr, 2023 | 13:16h | UTC

Changes in Hydroxyurea Use Among Youths Enrolled in Medicaid With Sickle Cell Anemia After 2014 Revision of Clinical Guidelines – JAMA Network Open

Original Guideline: National Heart, Lung, and Blood Institute. Evidence-based management of sickle cell disease: expert panel report, 2014

Commentary on Twitter

Hydroxyurea prescribing in youths with sickle cell anemia insured by Medicaid modestly after the @nih_nhlbi guidelines recommended hydroxurea in 2014. Increasing hydroxyurea use may require a multifaceted approach. https://t.co/tkY0HiMvkv

— JAMA Network Open (@JAMANetworkOpen) March 24, 2023

Review | Use of cardio-pulmonary ultrasound in the neonatal intensive care unit

5 Apr, 2023 | 12:58h | UTC

Use of Cardio-Pulmonary Ultrasound in the Neonatal Intensive Care Unit – Children

Review | Evaluation of the hypotensive preterm infant: evidence-based practice at the bedside?

5 Apr, 2023 | 12:55h | UTC

Evaluation of the Hypotensive Preterm Infant: Evidence-Based Practice at the Bedside? – Children

Review | Respiratory management of the preterm infant: supporting evidence-based practice at the bedside

5 Apr, 2023 | 12:53h | UTC

Respiratory Management of the Preterm Infant: Supporting Evidence-Based Practice at the Bedside – Children

Consensus Paper | Definition and criteria for diagnosing cesarean scar disorder

5 Apr, 2023 | 12:51h | UTC

Definition and Criteria for Diagnosing Cesarean Scar Disorder – JAMA Network Open

Pharmacotherapy of obesity: an update on the available medications and drugs under investigation

5 Apr, 2023 | 12:50h | UTC

Pharmacotherapy of obesity: an update on the available medications and drugs under investigation – eClinicalMedicine

SR | Efficacy and tolerance of second-generation antipsychotics in anorexia nervosa

5 Apr, 2023 | 12:48h | UTC

Efficacy and tolerance of second-generation antipsychotics in anorexia nervosa: A systematic scoping review – PLOS One

M-A | Efficacy of flash glucose monitoring in type 1 and type 2 diabetes

5 Apr, 2023 | 12:46h | UTC

Efficacy of Flash Glucose Monitoring in Type 1 and Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials – Frontiers in Clinical Diabetes and Healthcare

Analysis | Global coverage and design of sugar-sweetened beverage taxes

5 Apr, 2023 | 12:43h | UTC

Global Coverage and Design of Sugar-Sweetened Beverage Taxes – JAMA Network Open

WHO manual on sugar-sweetened beverage taxation policies to promote healthy diets.

M-A: Outcomes following taxation of sugar-sweetened beverages.

Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents – Pediatrics

Cutting back on sugar-sweetened beverages: What works? – Cochrane Library

Association of a Beverage Tax on Sugar-Sweetened and Artificially Sweetened Beverages With Changes in Beverage Prices and Sales at Chain Retailers in a Large Urban Setting – JAMA

Association between tax on sugar sweetened beverages and soft drink consumption in adults in Mexico: open cohort longitudinal analysis of Health Workers Cohort Study – The BMJ

Potential impact on prevalence of obesity in the UK of a 20% price increase in high sugar snacks: modelling study – The BMJ

Changes in food purchases after the Chilean policies on food labelling, marketing, and sales in schools: a before and after study – The Lancet Planetary Health

Association of a Sweetened Beverage Tax With Soda Consumption in High School Students – JAMA Pediatrics

Sugar-sweetened beverage taxes: Lessons to date and the future of taxation – PLOS Medicine

Banning the promotion of soft drinks could be more effective than a sugar tax – The Conversation

Sugar tax: why health experts want it but politicians and industry are resisting – The Guardian

Commentary on Twitter

With 105 national SSB taxes in effect covering 51% of the world’s population, SSB taxes are no longer a novel policy tool. https://t.co/P0TvIdB4D3

— JAMA Network Open (@JAMANetworkOpen) March 29, 2023

M-A | Efficacy of atropine for myopia control in children

5 Apr, 2023 | 12:45h | UTC

Efficacy of atropine for myopia control in children: A meta-analysis of randomized controlled trials – Journal of Family Medicine and Primary Care

RCT | Effect of low-concentration atropine eyedrops vs. placebo on myopia incidence in children

Crossover RCT | Spectacle lenses with highly aspherical lenslets for slowing myopia.

RCT | Effect of text messaging parents of school-aged children on outdoor time to control myopia.

RCT | Myopia control effect of repeated low-level red-light therapy in children.

RCT: Spectacle lenses with aspherical lenslets for myopia control vs. single-vision spectacle lenses.

Randomized trial: Effect of High add power, medium add power, or single-vision contact lenses on myopia progression in children

RCT | Mindfulness therapy proves more effective and affordable than cognitive behavioral therapy for depression

4 Apr, 2023 | 14:04h | UTC

Summary: The LIGHTMind Randomized Clinical Trial studied 410 adults with mild to moderate depression, comparing the clinical effectiveness and cost-effectiveness of practitioner-supported mindfulness-based cognitive therapy self-help (MBCT-SH) to practitioner-supported cognitive behavioral therapy self-help (CBT-SH). The trial provided participants with either an MBCT-SH or CBT-SH workbook and six support sessions with a trained practitioner. Depressive symptom severity was measured using the Patient Health Questionnaire (PHQ-9) score at 16 weeks after randomization.

Results showed that MBCT-SH led to significantly greater reductions in depressive symptoms and was more cost-effective than CBT-SH. The between-group difference was 1.5 PHQ-9 points, and MBCT-SH cost health services £526 ($631) less per participant over a 42-week follow-up period. A substantial portion of this cost difference was due to additional face-to-face individual psychological therapy accessed by CBT-SH participants outside of the study intervention.

The trial concluded that offering practitioner-supported MBCT-SH for mild to moderate depression could improve outcomes and save money compared to CBT-SH. To translate these findings into practice, proper training and supervision for practitioners delivering MBCT-SH are necessary. Future research should focus on corroborating and extending these findings, exploring factors contributing to MBCT-SH’s relative effectiveness, and examining potential barriers and facilitators for successful implementation in routine clinical practice.

Article: Clinical Effectiveness and Cost-Effectiveness of Supported Mindfulness-Based Cognitive Therapy Self-help Compared With Supported Cognitive Behavioral Therapy Self-help for Adults Experiencing Depression: The Low-Intensity Guided Help Through Mindfulness (LIGHTMind) Randomized Clinical Trial – JAMA Psychiatry

Commentary:

Mindfulness better than CBT for treating depression, study finds – The Guardian

Practitioner-Supported Mindfulness-Based Cognitive Therapy Aids Depression – HealthDay

Commentary on Twitter

Practitioner-supported mindfulness-based cognitive therapy self-help for mild-moderate depression is clinically- and cost-effective compared to currently recommended practitioner-support CBT self-help. https://t.co/H23AfwiO7X pic.twitter.com/xTHzYG4oqg

— JAMA Psychiatry (@JAMAPsych) March 22, 2023

What is acute kidney injury? A visual guide

4 Apr, 2023 | 14:02h | UTC

What is acute kidney injury? A visual guide – Nature

Opinion | AI-generated medical advice—GPT and beyond

4 Apr, 2023 | 14:00h | UTC

AI-Generated Medical Advice—GPT and Beyond – JAMA (free for a limited period)

The use of ChatGPT and other large language models in surgical science – BJS Open

ChatGPT vs. NCI: analyzing the quality of cancer information on myths and misconceptions

ChatGPT has many uses. Experts explore what this means for healthcare and medical research – The Conversation

Artificial Intelligence in Medicine & ChatGPT: De-Tether the Physician – Journal of Medical Systems (if the link is paywalled, try this one)

Can artificial intelligence help for scientific writing? – Critical Care

Artificial intelligence in academic writing: a paradigm-shifting technological advance

Performance of ChatGPT on USMLE: potential for AI-assisted medical education using large language models

Perspective | ChatGPT-assisted diagnosis: is the future suddenly here?

Perspective | Generating scholarly content with ChatGPT: ethical challenges for medical publishing

ChatGPT: Will It Transform the World of Health Care? – UCSF Department of Medicine

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

ChatGPT: five priorities for research – Nature

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

ChatGPT is fun, but not an author – Science

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Abstracts written by ChatGPT fool scientists

RCT | No significant fracture reduction from monthly 60,000 IU vitamin D3 supplementation

4 Apr, 2023 | 13:58h | UTC

The effect of monthly vitamin D supplementation on fractures: a tertiary outcome from the population-based, double-blind, randomised, placebo-controlled D-Health trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

RCT | Supplemental Vitamin D does not reduce incident fractures in midlife and older adults.

Comparison of fracture risk using different supplemental doses of vitamin D, calcium or their combination: a network meta-analysis of randomised controlled trials – BMJ Open

Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis – JAMA

Contrary to prior studies, new research finds no heightened postoperative risk after a recent covid-19 infection

4 Apr, 2023 | 13:54h | UTC

Estimated Risk of Adverse Surgical Outcomes Among Patients With Recent COVID-19 Infection Using Target Trial Emulation Methods – JAMA Network Open

Commentaries:

COVID infection within 60 days not tied to adverse postsurgical outcomes – CIDRAP

Adverse Postoperative Outcomes Not Increased With Recent COVID-19 – HealthDay

ASA and APSF statement on perioperative testing for the COVID-19 virus.

Surgical Triage and Timing for Patients with COVID: A Guidance Statement from the Society of Thoracic Surgeons – Annals of Thoracic Surgery

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

Bivalent Booster | Observational data suggests no increased cardiovascular risks compared to monovalent vaccine

4 Apr, 2023 | 13:55h | UTC

Stroke, Myocardial Infarction, and Pulmonary Embolism after Bivalent Booster – New England Journal of Medicine

Commentary: Similarly Low Risk of CV Events With Bivalent and Monovalent mRNA Boosters – TCTMD

Commentary on Twitter

In this French study, the risk of cardiovascular events was similar among recipients of the bivalent Pfizer–BioNTech vaccine and the original monovalent vaccine 21 days after the booster dose. https://t.co/FUZbbsn82I pic.twitter.com/ki0FPeutNm

— NEJM (@NEJM) March 29, 2023