RCT | Supplemental Vitamin D does not reduce incident fractures in midlife and older adults.

Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Daily Vitamin D supplements don’t lower risk of bone fractures, study finds – STAT

Related:

Comparison of fracture risk using different supplemental doses of vitamin D, calcium or their combination: a network meta-analysis of randomised controlled trials – BMJ Open

Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis – JAMA

Commentary on Twitter

A study ancillary to a large trial showed that supplemental vitamin D3 did not lower the risk of fractures among generally healthy midlife and older adults not selected for vitamin D deficiency, low bone mass, or osteoporosis. https://t.co/vVTlizdffG pic.twitter.com/hQHJ7JizaV

— NEJM (@NEJM) July 27, 2022