All Posts
Review | De-escalation of antiplatelet therapy in patients with coronary artery disease: time to change our strategy?
6 Apr, 2023 | 13:14h | UTC
Podcast | Congenital hypothyroidism
6 Apr, 2023 | 13:11h | UTC#78: Congenital Hypothyroidism – The Cribsiders
Podcast | HIV in primary care
6 Apr, 2023 | 13:13h | UTC#388 HIV in Primary Care with Dr. Jonathan J. “JJ” Nunez MD – The Curbsiders
Podcast | Childhood-Onset SLE
6 Apr, 2023 | 13:12h | UTC#77: Childhood-Onset SLE – Is It Sometimes Lupus? – The Cribsiders
Cohort Study | Barriers to starting direct-acting antiviral treatment despite access for HIV & hepatitis C patients
6 Apr, 2023 | 13:09h | UTCInvited Commentary: The road to hepatitis C virus elimination – The Lancet Public Health
RCT | Safety and efficacy of Pitolisant in children aged 6 years or older with narcolepsy with or without cataplexy
6 Apr, 2023 | 13:08h | UTCSafety and efficacy of pitolisant in children aged 6 years or older with narcolepsy with or without cataplexy: a double-blind, randomised, placebo-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: Pitolisant Improves Pediatric Narcolepsy Symptoms Regardless of Cataplexy in Phase 3 Study – Neurology Live
SR | Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years
6 Apr, 2023 | 13:06h | UTC
SR | Insufficient evidence on skin-sparing mastectomy efficacy and safety for breast cancer
6 Apr, 2023 | 13:04h | UTCSkin‐sparing mastectomy for the treatment of breast cancer – Cochrane Database of Systematic Reviews
M-A | Comparison of the diagnostic accuracies of monocyte distribution width, procalcitonin, and C-reactive protein for sepsis
6 Apr, 2023 | 13:00h | UTC
Cohort Study | Maternal cardiac arrest: occurrence, survival, and influencing factors
6 Apr, 2023 | 12:59h | UTCCardiac Arrest During Delivery Hospitalization: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Cardiac Arrest During Delivery Hospitalization – American College of Cardiology
Cardiac Arrest During Childbirth Is Rare, But Some Women Face Higher Risks – HealthDay
Commentary on Twitter
https://twitter.com/AnnalsofIM/status/1636095275545632768
Cohort Study | Multimodal prediction of favorable outcome after cardiac arrest
6 Apr, 2023 | 13:01h | UTC
RCT | Over-the-scope clips show lower rebleeding rates in nonvariceal GI bleeding
6 Apr, 2023 | 12:57h | UTCComparison of Over-the-Scope Clips to Standard Endoscopic Treatment as the Initial Treatment in Patients With Bleeding From a Nonvariceal Upper Gastrointestinal Cause: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Over-the-Scope Clip Beneficial for Nonvariceal Upper GI Bleeding – HealthDay
Commentary on Twitter
A new RCT found that over-the-scope-clips may be more effective than standard treatment for some patients with nonvariceal upper #GastrointestinalBleeding: https://t.co/GWG70CWmlt pic.twitter.com/Foq2qQZTEc
— Annals of Int Med (@AnnalsofIM) March 7, 2023
RCT | Etrasimod outperforms placebo in ulcerative colitis induction & maintenance
6 Apr, 2023 | 12:56h | UTC
Commentary on Twitter
Just published @TheLancet – Sandborn et al – Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies https://t.co/BVDWtESWLP#gitwitter #ibd #ulcerativecolitis #ECCO23 #ECCO2023 pic.twitter.com/hjyJ0tdtWd
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) March 3, 2023
SR | Induction of labor at or near term for suspected fetal macrosomia
6 Apr, 2023 | 12:55h | UTC
WHO Report | 1 in 6 people globally affected by infertility
5 Apr, 2023 | 13:47h | UTCNews Release: 1 in 6 people globally affected by infertility – World Health Organization
Report: Infertility Prevalence Estimates, 1990–2021 – World Health Organization
Key facts: Infertility – World Health Organization
Commentaries:
Infertility affects a ‘staggering’ 1 in 6 people worldwide, WHO says – CNN
One in six people worldwide affected by infertility, WHO reports – The Guardian
Commentary on Twitter (thread – click for more)
Around 1 in 6 people is affected by infertility in their lifetime: 🆕 WHO research.
This shows an urgent need to increase access to affordable, high-quality fertility care https://t.co/od9QQ9Qjvj pic.twitter.com/R8JtezT0kZ
— World Health Organization (WHO) (@WHO) April 4, 2023
ACC/AHA blood pressure categories | Systematic review of adverse pregnancy outcomes in early pregnancy
6 Apr, 2023 | 12:53h | UTC
Commentary on Twitter
https://twitter.com/AJOG_thegray/status/1641772214830727168
RCT | Assessing low-dose ketamine’s antidepressant & antisuicidal effects in patients with treatment-resistant depression
5 Apr, 2023 | 13:44h | UTC
Commentary on Twitter
RCT: ketamine infusion (0.5 mg/kg) is a safe and effective treatment for patients with TRD and prominent suicidal ideation vs. midazolam. Response was noted when the current depressive episode lasted for <24 months and the number of failed AD is ≤4 https://t.co/QKNy8bUKBK pic.twitter.com/GyfQp0pmpO
— P𝘧OL (@psychopharmacol) April 4, 2023
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
5 Apr, 2023 | 13:45h | UTC
Commentary on Twitter
Management of severe community-acquired pneumonia: @EuroRespSoc @ESICM @ESCMID @ALATorax international guidelines
➡️ evidence-based recommendations for diagnosis, empirical treatment, ABTs
➡️ current knowledge gaps
➡️ recommendations for future research
🖇️ https://t.co/qhe1wlgN9t pic.twitter.com/LMNCbauYfs— Intensive Care Medicine (@yourICM) April 4, 2023
M-A | Impact of antihypertensive therapy on maternal & neonatal outcomes in mild-moderate pregnancy hypertension
6 Apr, 2023 | 12:51h | UTC
Cohort Study | Pregnancy glucose intolerance, even below diabetes criteria, linked to increased risk of type 2 diabetes
5 Apr, 2023 | 13:42h | UTCGlucose intolerance in pregnancy and risk of early-onset type 2 diabetes: a population-based cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Review | Diagnosis and treatment of acute myocarditis
5 Apr, 2023 | 13:40h | UTCDiagnosis and Treatment of Acute Myocarditis: A Review – JAMA (free for a limited period)
RCT | Endovascular treatment vs. no treatment after 6-24h in ischemic stroke patients with collateral flow on CT angiography
5 Apr, 2023 | 13:38h | UTCEndovascular treatment versus no endovascular treatment after 6–24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems
5 Apr, 2023 | 13:36h | UTCCommentary: Take Your Meds – Science
Commentary on Twitter
Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems https://t.co/WSyYu24Iw1 – a new review discussing how delivery systems can mitigate impediments to adherence such as frequent dosing, adverse effects and a delayed onset of action pic.twitter.com/xoSJYFo0Qs
— Nature Reviews Drug Discovery (@NatRevDrugDisc) March 28, 2023
Review | Computed tomographic angiography in coronary artery disease
5 Apr, 2023 | 13:33h | UTCComputed tomographic angiography in coronary artery disease – EuroIntervention
RCT | Enzalutamide versus standard antiandrogen therapy in hormone-sensitive prostate cancer with metastasis
5 Apr, 2023 | 13:30h | UTCTestosterone suppression plus enzalutamide versus testosterone suppression plus standard antiandrogen therapy for metastatic hormone-sensitive prostate cancer (ENZAMET): an international, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
News Release: ENZAMET shows promise as prostate cancer treatment – University of Adelaide