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U.S. Study: Ultraprocessed Foods Now Comprise 2/3 of Calories in Children and Teen Diets.

16 Aug, 2021 | 00:41h | UTC

Trends in Consumption of Ultraprocessed Foods Among US Youths Aged 2-19 Years, 1999-2018 – JAMA (free for a limited period)

Editorial: Intake of Ultraprocessed Foods Among US Youths: Health Concerns and Opportunities for Research and Policy (free for a limited period)

News release: Ultraprocessed Foods Now Comprise 2/3 of Calories in Children and Teen Diets – Tufts University

Commentaries:

Ultra-processed foods now account for two-thirds of calories in the diets of children and teens – CNN

If You Think Kids Are Eating Mostly Junk Food, A New Study Finds You’re Right – NPR

Related:

Ultra-processing is the new frontier in public health policy—reflections on the National Food Strategy – The BMJ Opinion

Cohort Study: Association Between Consumption of Ultra-processed Foods and All Cause Mortality

Study: Association Between Ultraprocessed Food Consumption and Risk of Mortality Among Middle-aged Adults

Research: Consumption of Ultra-Processed Foods and Cancer Risk

Randomized Trial: Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain

Ultra-Processed Foods and Incident Cardiovascular Disease in the Framingham Offspring Study

Cohort study: Higher intake of ultra-processed food linked to increased risk of inflammatory bowel disease.

 

Commentary on Twitter (thread – click for more)

https://twitter.com/Dmozaffarian/status/1425155359849730052

 

How do vaccinated people spread Delta? What the science says.

13 Aug, 2021 | 09:55h | UTC

How do vaccinated people spread Delta? What the science says – Nature

 

Opinion: Making vaccines available to other countries before offering domestic booster vaccinations.

13 Aug, 2021 | 09:48h | UTC

Making Vaccines Available to Other Countries Before Offering Domestic Booster Vaccinations – JAMA

 

Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine).

13 Aug, 2021 | 09:58h | UTC

Could This Be Our First Effective, Inexpensive, Widely Available Outpatient Treatment for COVID-19? – HIV and ID Observations

Related: Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19

 

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

13 Aug, 2021 | 10:01h | UTC

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison – American Family Physician

Related:

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

 

Opinion: Time for a smart approach to boosters.

13 Aug, 2021 | 09:51h | UTC

Time for a Smart Approach to Boosters – Think Global Health

 

Antibody response to COVID-19 vaccination in adults with hematologic malignant disease.

13 Aug, 2021 | 09:47h | UTC

Antibody Response to COVID-19 Vaccination in Adults With Hematologic Malignant Disease – JAMA Oncology

 

Commentary on Twitter

 

How COVID-19 will change the management of other respiratory viral infections.

13 Aug, 2021 | 09:52h | UTC

How COVID-19 will change the management of other respiratory viral infections – Intensive Care Medicine

 

Commentary on Twitter

 

Guideline: Non-surgical interventions for lumbar spinal stenosis leading to neurogenic claudication.

13 Aug, 2021 | 09:03h | UTC

Non-Surgical Interventions for Lumbar Spinal Stenosis Leading To Neurogenic Claudication: A Clinical Practice Guideline – Journal of Pain

 

German S3-Guideline on the treatment of Psoriasis vulgaris.

13 Aug, 2021 | 09:45h | UTC

German S3-Guideline on the treatment of Psoriasis vulgaris, adapted from EuroGuiDerm – Part 1: Treatment goals and treatment recommendations – Journal of the German Society of Dermatology

 

M-A: Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients.

13 Aug, 2021 | 09:01h | UTC

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis – Intensive Care Medicine

 

Commentary on Twitter

 

First World Consensus Conference on Pancreas Transplantation.

13 Aug, 2021 | 09:43h | UTC

Part I – methods and results of literature search – American Journal of Transplantation

Part II – recommendations – American Journal of Transplantation

 

Study shows clinicians significantly overestimate the benefits of treatment to individual patients.

13 Aug, 2021 | 08:58h | UTC

Clinician Conceptualization of the Benefits of Treatments for Individual Patients – JAMA Network Open

 

Commentary on Twitter

 

Cohort study: Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease.

13 Aug, 2021 | 08:56h | UTC

Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease – European Heart Journal

 

Commentary on Twitter

 

European guideline and expert statements on the management of narcolepsy in adults and children.

13 Aug, 2021 | 09:02h | UTC

European guideline and expert statements on the management of narcolepsy in adults and children – European Journal of Neurology

 

M-A of randomized trials: proton pump inhibitors for gastro-esophageal reflux disease does not improve outcomes in patients with asthma.

13 Aug, 2021 | 08:53h | UTC

Randomised trials of proton pump inhibitors for gastro-oesophageal reflux disease in patients with asthma: an updated systematic review and meta-analysis – BMJ Open

 

Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer – “This trial provides the first clinical evidence that sparing the hippocampus during PCI in patients with SCLC better preserves cognitive function”.

13 Aug, 2021 | 08:54h | UTC

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study – Journal of Clinical Oncology

 

RCT: Effect of sacrospinous hysteropexy with graft vs vaginal hysterectomy with uterosacral ligament suspension on treatment failure in women with uterovaginal prolapse.

13 Aug, 2021 | 08:52h | UTC

Effect of sacrospinous hysteropexy with graft vs vaginal hysterectomy with uterosacral ligament suspension on treatment failure in women with uterovaginal prolapse: 5-year results of a randomized clinical trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

 

Commentary on Twitter (video summary)

 

Review: Oxygenation strategies after extubation of critically ill and postoperative patients.

13 Aug, 2021 | 08:49h | UTC

Oxygenation strategies after extubation of critically ill and postoperative patients – Journal of Intensive Medicine

 

Review: Preoperative laboratory testing in elderly patients.

13 Aug, 2021 | 08:50h | UTC

Preoperative laboratory testing in elderly patients – Current Opinion in Anesthesiology

 

Global Incidence and Mortality of Gastric Cancer, 1980-2018

13 Aug, 2021 | 08:45h | UTC

Global Incidence and Mortality of Gastric Cancer, 1980-2018 – JAMA Network Open

 

Opinion | Doctors pledge to do no harm. The entire health care sector should do the same by battling climate change

13 Aug, 2021 | 08:47h | UTC

Doctors pledge to do no harm. The entire health care sector should do the same by battling climate change – STAT

 

RCT: third dose of Moderna mRNA vaccine increases immunity in transplant recipients.

12 Aug, 2021 | 09:56h | UTC

Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients – New England Journal of Medicine

Editorial: Third Time’s a Charm — Covid-19 Vaccine Hope for Solid-Organ Transplant Recipients

Related:

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

[Preprint] 3rd AstraZeneca shot gives strong immunity.

 

Commentaries on Twitter

https://twitter.com/hildabast/status/1425576801850433537

 

RCT: Evaluation of Moderna mRNA vaccine in adolescents.

12 Aug, 2021 | 09:58h | UTC

Evaluation of mRNA-1273 SARS-CoV-2 Vaccine in Adolescents – New England Journal of Medicine

Related:

Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.

RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site pain (in 79 to 86% of participants), fatigue (in 60 to 66%), and headache (in 55 to 65%).

 

Commentaries on Twitter

 

Moderna may be superior to Pfizer against Delta variant — breakthrough odds rise with time.

12 Aug, 2021 | 09:54h | UTC

Moderna may be superior to Pfizer against delta variant — breakthrough odds rise with time – CNBC

Original Study 1 (preprint): Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence – medRxiv

Original Study 2 (preprint): Neutralizing antibody responses to SARS-CoV-2 variants in vaccinated Ontario long-term care home residents and workers – medRxiv

Related:

Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.

 

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