All Posts
Economic evaluation: cost-effectiveness of installing barriers at bridge and cliff sites for suicide prevention in Australia.
14 Apr, 2022 | 08:01h | UTCInvited Commentary: Rethinking Suicide Prevention as a Public Health Issue – JAMA Network Open
Commentary on Twitter
This economic evaluation found that barriers installed at multiple bridge sites – but not cliffs – in Australia were a cost-effective measure in reducing suicide rates at bridges. https://t.co/5D0MIzLZ1Y
— JAMA Network Open (@JAMANetworkOpen) April 5, 2022
M-A: Diagnostic validity and clinical utility of genetic testing for hypertrophic cardiomyopathy.
14 Apr, 2022 | 08:09h | UTC
Cohort Study: Association of bone mineral density testing with risk of major osteoporotic fractures among older men receiving androgen deprivation therapy to treat localized or regional prostate cancer.
14 Apr, 2022 | 07:59h | UTCCommentary: Men treated for prostate cancer have increased fracture risk, yet few complete DXA screening – HealthImaging
Commentary on Twitter
In this cohort study, osteoporosis screening rates for over 50,000 elderly men with prostate cancer receiving hormonal therapy nationwide were very low; men who were screened were less likely to suffer major fractures in follow-up. https://t.co/RMz1bvEgiA
— JAMA Network Open (@JAMANetworkOpen) April 1, 2022
Review | Induction therapy prior to autologous stem cell transplantation (ASCT) in newly diagnosed multiple myeloma.
14 Apr, 2022 | 08:03h | UTC
Review | Breast MRI during pregnancy and lactation: clinical challenges and technical advances.
14 Apr, 2022 | 07:57h | UTC
Review | Role of the radiologist in the diagnosis and management of the two forms of hepatic echinococcosis.
14 Apr, 2022 | 07:55h | UTC
Cohort Study: Mifepristone and misoprostol for undesired pregnancy of unknown location.
14 Apr, 2022 | 07:53h | UTCMifepristone and Misoprostol for Undesired Pregnancy of Unknown Location – Obstetrics & Gynecology
Development and validation of a decision analytical model for posttreatment surveillance for patients with oropharyngeal carcinoma.
14 Apr, 2022 | 07:52h | UTC
Evaluation of information theoretic network meta-analysis to rank first-line anticancer regimens for hormone receptor–positive, ERBB2-negative metastatic breast cancer.
14 Apr, 2022 | 07:48h | UTCInvited Commentary: Navigating Systemic Therapeutic Options for First-Line Metastatic Hormone Receptor–Positive, ERBB2-Negative Breast Cancer Treatment – JAMA Network Open
Review | Machine learning for medical imaging: methodological failures and recommendations for the future.
14 Apr, 2022 | 07:46h | UTC
USPSTF draft statement recommends screening for anxiety and depression in children and adolescents ages 8 to 18 years.
13 Apr, 2022 | 11:05h | UTCDraft Statements:
Screening for Anxiety in Children and Adolescents – US Preventive Services Task Force
Commentary:
USPSTF Recommends Anxiety, Depression Screening for Children – HealthDay
The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019.
13 Apr, 2022 | 11:03h | UTCInvited Commentary: The burden of young people’s mental health conditions in Europe: No cause for complacency – The Lancet Regional Health Europe
Related:
Commentary on Twitter
See our new @IHME_UW analysis from on the #burden of #mentaldisorders, substance use disorders & self-harm among young people in Europe. In 2019 there were 16,983 MDs cases/100.000. In last 30 yrs YLD for eating disorders & drug use disorders increased. https://t.co/hMbHDlPuur pic.twitter.com/Rt4Iq4tpAA
— Maciej Banach (@maciejbanach) April 2, 2022
(Article and images under a CC BY 4.0 license)
Review: Diagnosis and treatment of pulmonary arterial hypertension.
13 Apr, 2022 | 10:58h | UTCDiagnosis and Treatment of Pulmonary Arterial Hypertension: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis and Treatment of Pulmonary Arterial Hypertension – JAMA
Commentary on Twitter
This review summarizes current evidence regarding diagnosis and treatment of pulmonary arterial #hypertension. https://t.co/Ebo33PD8Qq
— JAMA (@JAMA_current) April 12, 2022
RCT: A home-based, walking exercise behavior change intervention increased walking distance in adults with peripheral artery disease.
13 Apr, 2022 | 11:02h | UTCEffect of a Home-Based, Walking Exercise Behavior Change Intervention vs Usual Care on Walking in Adults With Peripheral Artery Disease: The MOSAIC Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
In this study, among adults with peripheral artery disease, a home-based, #walking #exercise behavior change intervention, compared with usual care, increased 6-minute walking distance at 3 months. https://t.co/5ea3YOWlN0 @LindsayBearne pic.twitter.com/s06ONnki9y
— JAMA (@JAMA_current) April 12, 2022
Perspective: The concept of classical herd immunity may not apply to COVID-19.
13 Apr, 2022 | 10:54h | UTCNews Release: NIH experts discuss controlling COVID-19 in commentary on herd immunity – NIH News Releases
Commentary on Twitter
Co-authored by Dr. Anthony Fauci and two other @NIAIDNews'ers
"We no longer need the elusive concept of 'herd immunity' as an aspirational goal: COVID-19 control is already within our grasp."https://t.co/kvYfpsXviB https://t.co/aaiGcb3qtL pic.twitter.com/6yrcsKbUGi
— Alexander Tin (@Alexander_Tin) March 31, 2022
Cluster RCT: A shorter antimicrobial prophylaxis duration (less than 24 hours after surgery) is noninferior to a more extended regimen (24-48 hours) after clean orthopedic surgery.
13 Apr, 2022 | 10:56h | UTC
Commentary on Twitter
Cluster RCT of patients who underwent clean orthopedic surgery found shorter antimicrobial prophylaxis duration (<24h postop) was noninferior to longer duration (<48h) in preventing health care associated infections and across a range of clinical outcomes. https://t.co/FFzxNiHxet
— JAMA Network Open (@JAMANetworkOpen) April 12, 2022
M-A: Sodium-glucose Cotransporter 2 inhibitors are associated with reduced risk of hyperkalemia in people with type 2 diabetes.
13 Apr, 2022 | 10:52h | UTC
RCT: Dapagliflozin did not significantly improve glycemic control in children and young adults with type 2 diabetes.
13 Apr, 2022 | 10:46h | UTCEfficacy and safety of dapagliflozin in children and young adults with type 2 diabetes: a prospective, multicentre, randomised, parallel group, phase 3 study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
RCT: Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis.
13 Apr, 2022 | 10:31h | UTCNews Release: Breakthrough success in provision of automated psychological therapy using virtual reality – University of Oxford
Commentary from the author on Twitter
gameChange results are out! Six sessions of automated VR therapy reduced agoraphobic avoidance and distress for patients with psychosis. People who were mainly housebound had large benefits maintained at 6mths. @OxPsychiatry @NIHRresearch @TheLancetPsych https://t.co/VE9oxsa5cf pic.twitter.com/KAvuLqHtiI
— Daniel Freeman (@ProfDFreeman) April 6, 2022
Review | Less is more: deprescribing medications in older adults with kidney disease.
13 Apr, 2022 | 10:44h | UTCLess is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360
Related:
AGA clinical practice update on de-prescribing of proton pump inhibitors.
Development of a metric to detect and decrease low-value prescribing in older adults.
Deprescribing in palliative patients with cancer: a concise review of tools and guidelines.
A narrative review of evidence to guide deprescribing among older adults.
Polypharmacy Management in Older Patients – Mayo Clinic Proceedings
Eliminating Medication Overload: A National Action Plan
Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
New insights into the genetic etiology of Alzheimer’s disease and related dementias.
13 Apr, 2022 | 10:26h | UTCNews Release:
Commentaries:
42 previously unknown genes discovered for Alzheimer’s disease – CNN
Alzheimer’s disease research takes ‘major leap forward’ – BBC
Commentary on Twitter
A meta-analysis in @NatureGenet of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia. https://t.co/EAtdlRozld pic.twitter.com/5rtWWt4HyS
— Nature Portfolio (@NaturePortfolio) April 11, 2022
Cluster RCT: A multifaceted intervention did not reduce catheter related bloodstream infections in patients on hemodialysis.
13 Apr, 2022 | 10:29h | UTC
Opinion | Time to rethink the scientific CV.
13 Apr, 2022 | 10:23h | UTCTime to rethink the scientific CV – Nature
Commentary on Twitter
As institutions and funders around the world reassess their approach to researcher evaluations, there’s a growing call to revamp the academic CVs used to support applications for jobs, funding, promotions and awards. Read the @NatureCareers feature. https://t.co/ZGxrJrA1ZG
— Nature Portfolio (@NaturePortfolio) April 12, 2022
Cohort Study: Increased thoracic aortic diameter is associated with increased risk of cardiovascular events and mortality among women and men.
13 Apr, 2022 | 10:20h | UTCThoracic Aortic Diameter and Cardiovascular Events and Mortality among Women and Men – Radiology
News Release: Increased aortic diameter raises risk of heart attack, stroke – Radiological Society of North America
RCT: In patients undergoing knee replacement surgery, the administration of periarticular liposomal bupivacaine did not improve postoperative recovery or pain compared with bupivacaine hydrochloride alone.
13 Apr, 2022 | 10:16h | UTC