Archives
Higher Doses of Antidepressants “Not Optimal”, According to New Review
14 Jun, 2019 | 02:32h | UTCHigher doses of antidepressants “not optimal”, according to new review – The Mental Elf (free)
Original Article: Meta-analysis: Optimal Dose of Antidepressants in Major Depression (free study and commentaries)
[Abstract Only] Risks of 23 Specific Malformations Associated with Prenatal Exposure to 10 Antiepileptic Drugs
14 Jun, 2019 | 02:33h | UTCRisks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs – Neurology (link to abstract – $ for full-text)
Commentaries: Epilepsy drugs linked to higher risk of birth defects, study says – CNN (free) AND Study Confirms Teratogenicity of Valproic Acid, Topiramate – MPR (free)
Related: Guideline: Valproate Use in Women and Girls Of Childbearing Years (free) AND Research: Topiramate Use Early in Pregnancy and the Risk of Oral Clefts (free)
Influenza Virus-related Critical Illness: Prevention, Diagnosis, Treatment
14 Jun, 2019 | 02:30h | UTCInfluenza virus-related critical illness: prevention, diagnosis, treatment – Critical Care (free)
Cohort Study: Gabapentinoids linked to Increased Risk of Suicidal Behavior
14 Jun, 2019 | 02:26h | UTCEditorial: Gabapentinoids linked to new risks, including suicidal behavior (free)
Commentaries: Epilepsy drugs linked to increased risk of suicidal behavior, particularly in young people – The BMJ (free) AND Expert reaction to study on gabapentinoids and risk of suicidal behavior – Science Media Centre (free)
Review of Current Guidelines on the Management of Gestational Diabetes Mellitus
14 Jun, 2019 | 02:29h | UTC
Thu June 13 – 10 Stories of The Day!
13 Jun, 2019 | 10:33h | UTC
2 – Infective Endocarditis in Patients With Positive Blood Cultures – American College of Cardiology (free)
Original Article: Prevalence of infective endocarditis in patients with positive blood cultures: a Danish nationwide study – European Heart Journal (link to abstract – $ for full-text)
3 – Cardiovascular Corner: Low Lipids, Metformin, and Plant-Based Diets – JAMA (free for a limited period)
4 – To Save The Science Poster, Researchers Want To Kill It And Start Over – NPR (free)
Related Video: How to create a better research poster in less time (including templates) (free)
5 – Care Redesign Survey: The Power of Palliative Care – NEJM Catalyst (free)
6 – Never Say ‘Die’: Why So Many Doctors Won’t Break Bad News – Kaiser Health News (free)
7 – Ann Robinson’s journal review, 12 June 2019 – The BMJ Opinion (free)
8 – Environmental interventions to reduce the consumption of sugar‐sweetened beverages and their effects on health – Cochrane Library (free)
Summary: Cutting back on sugar-sweetened beverages: What works? – Cochrane Library (free)
Commentaries: New review suggests proven ways to cut back on sugary drinks – Reuters (free) AND Evidence on ways to reduce consumption of sugary drinks – Wiley (free)
Commentaries: Increasing red meat consumption linked with higher risk of premature death – Harvard T.H. Chan School of Public Health (free) AND The Swap: Less Processed Meat, More Plant-Based Foods May Boost Longevity – NPR (free)
[Abstract Only] Prevalence of Infective Endocarditis in Patients with Positive Blood Cultures According to the Organism
13 Jun, 2019 | 10:29h | UTCInfective Endocarditis in Patients With Positive Blood Cultures – American College of Cardiology (free)
Original Article: Prevalence of infective endocarditis in patients with positive blood cultures: a Danish nationwide study – European Heart Journal (link to abstract – $ for full-text)
Cardiovascular Corner: Low Lipids, Metformin, and Plant-Based Diets
13 Jun, 2019 | 07:41h | UTCCardiovascular Corner: Low Lipids, Metformin, and Plant-Based Diets – JAMA (free for a limited period)
Systematic Review of Perioperative Cardiac Risk Prediction Indices
13 Jun, 2019 | 10:30h | UTC
To Save The Science Poster, Researchers Want To Kill It And Start Over
13 Jun, 2019 | 07:39h | UTCTo Save The Science Poster, Researchers Want To Kill It And Start Over – NPR (free)
Related Video: How to create a better research poster in less time (including templates) (free)
Related Commentary on Twitter
Using the new #betterposter format at #ACSM19. It was the most productive poster presentation ever! Thanks @mikemorrison!#obesity #falls pic.twitter.com/X8oHAgs9ps
— Silvia Neri 🇧🇷 🇳🇱 (@silviagrneri) May 31, 2019
Care Redesign Survey: The Power of Palliative Care
13 Jun, 2019 | 07:37h | UTCCare Redesign Survey: The Power of Palliative Care – NEJM Catalyst (free)
Ann Robinson’s journal review—12 June 2019
13 Jun, 2019 | 07:34h | UTCAnn Robinson’s journal review, 12 June 2019 – The BMJ Opinion (free)
Never Say ‘Die’: Why So Many Doctors Won’t Break Bad News
13 Jun, 2019 | 07:35h | UTCNever Say ‘Die’: Why So Many Doctors Won’t Break Bad News – Kaiser Health News (free)
Meta-Analysis: CT Angiography in Patients with Stable Chest Pain
13 Jun, 2019 | 07:29h | UTC
Related Commentary on Twitter
Massive meta-analysis in @bmj_latest shows PPV of CCTA is as low as 51% in low risk pts sent for testing:https://t.co/ydHdqzFWSA
One could have easily predicted this as @khurramn1 and I laid out for stress testing.
Bottom line: don't send low risk patients for testing. pic.twitter.com/kcOabpZrjF
— Venk Murthy MD PhD (@venkmurthy) June 12, 2019
Systematic Review: Environmental Interventions to Reduce the Consumption of Sugar‐sweetened Beverages and Their Effects on Health
13 Jun, 2019 | 07:31h | UTCEnvironmental interventions to reduce the consumption of sugar‐sweetened beverages and their effects on health – Cochrane Library (free)
Summary: Cutting back on sugar-sweetened beverages: What works? – Cochrane Library (free)
Commentaries: New review suggests proven ways to cut back on sugary drinks – Reuters (free) AND Evidence on ways to reduce consumption of sugary drinks – Wiley (free)
Cohort Studies: Increasing Red Meat Consumption Linked to Increased Mortality
13 Jun, 2019 | 07:26h | UTCCommentaries: Increasing red meat consumption linked with higher risk of premature death – Harvard T.H. Chan School of Public Health (free) AND The Swap: Less Processed Meat, More Plant-Based Foods May Boost Longevity – NPR (free)
USPSTF Statement: Screening for HIV Infection
12 Jun, 2019 | 08:28h | UTCScreening for HIV Infection: US Preventive Services Task Force Recommendation Statement (free)
Editorials: HIV Screening and Preexposure Prophylaxis Guidelines: Following the Evidence (free) AND New USPSTF Guidelines for HIV Screening and Preexposure Prophylaxis (PrEP): Straight A’s (free)
Evidence Reports and Systematic Reviews: Screening for HIV Infection in Asymptomatic, Nonpregnant Adolescents and Adults (free) AND Screening for HIV Infection in Pregnant Women (free)
Author Interviews: Screening for HIV infection and Use of Preexposure Prophylaxis for Prevention of HIV Infection: US Preventive Services Task Force Recommendation Statements (free audio) AND HIV Screening and Preexposure Prophylaxis Guidelines (free audio)
Wed June 12 – 10 Stories of The Day!
12 Jun, 2019 | 10:52h | UTC
1 – Screening for HIV Infection: US Preventive Services Task Force Recommendation Statement (free)
Editorials: HIV Screening and Preexposure Prophylaxis Guidelines: Following the Evidence (free) AND New USPSTF Guidelines for HIV Screening and Preexposure Prophylaxis (PrEP): Straight A’s (free)
Evidence Reports and Systematic Reviews: Screening for HIV Infection in Asymptomatic, Nonpregnant Adolescents and Adults (free) AND Screening for HIV Infection in Pregnant Women (free)
Author Interviews: Screening for HIV infection and Use of Preexposure Prophylaxis for Prevention of HIV Infection: US Preventive Services Task Force Recommendation Statements (free audio) AND HIV Screening and Preexposure Prophylaxis Guidelines (free audio)
Editorials: HIV Screening and Preexposure Prophylaxis Guidelines: Following the Evidence (free) AND New USPSTF Guidelines for HIV Screening and Preexposure Prophylaxis (PrEP): Straight A’s (free)
Evidence Report and Systematic Review: Preexposure Prophylaxis for the Prevention of HIV Infection (free)
Author Interviews: Screening for HIV infection and Use of Preexposure Prophylaxis for Prevention of HIV Infection: US Preventive Services Task Force Recommendation Statements (free audio) AND HIV Screening and Preexposure Prophylaxis Guidelines (free audio)
Commentaries: Expert Panel Recommends Wider Use Of Daily Pill To Prevent HIV Infections – NPR (free) AND HIV prevention pill recommended for healthy people at risk – Reuters (free)
Related: British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject)
3 – Effect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Revisiting, Reframing, and Casting a New Light on Liberation From Mechanical Ventilation (free for a limited period)
See also: Visual Abstract (free)
“A review of more than 3,000 randomized clinical trials in NEJM, Lancet and JAMA reveals 396 medical reversals (results later shown to be wrong, usually in systematic reviews). 22 studies in pulmonary diseases and 45 in critical care medicine were affected.” (via @ClaudiaCDobler see Tweet)
Commentaries: More than six billion people at risk of dengue fever by 2080 – London School of Hygiene & Tropical Medicine (free) AND A new picture of dengue’s growing threat – Institute for Health Metrics and Evaluation (free) AND How Dengue, a Deadly Mosquito-Borne
Disease, Could Spread in a Warming World – The New York Times (10 articles per month are free)
Commentaries: Adverse effects of bolus fluid resuscitation—short-term benefit but long-term harm – The Lancet Respiratory Medicine (free) AND Doctors urge hospitals to reconsider the type of fluids used to treat children with sepsis – News Medical (free)
Original article: Mortality after Fluid Bolus in African Children with Severe Infection – New England Journal of Medicine (free)
Related: Implications for paediatric shock management in resource-limited settings: a perspective from the FEAST trial – Critical Care (free)
8 – Cancer treatment and survivorship statistics, 2019 – CA: A Cancer Journal for Clinicians (free)
Commentaries: Cancer survivors to reach 22 million by 2030 – UPI (free) AND Cancer survivors predicted to number over 22 million by 2030 – American Cancer Society (free)
9 – Aspirin for Primary Prevention of CV Events – American College of Cardiology (free)
Original Article: Aspirin for Primary Prevention of Cardiovascular Events – Journal of the American College of Cardiology (free)
Related: Aspirin for Primary Prevention: Is This the End of the Road? (selection of resources on the subject)
10 – Early Acid Suppression Therapy Exposure and Fracture in Young Children – Pediatrics (link to abstract – $ for full-text)
Commentary: Early exposure to antacids could put infants at risk for bone fractures during childhood – News Medical (free)
Randomized Trial: Pressure Support vs T-Piece Ventilation Strategies for Successful Extubation
12 Jun, 2019 | 08:23h | UTCEffect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Revisiting, Reframing, and Casting a New Light on Liberation From Mechanical Ventilation (free for a limited period)
See also: Visual Abstract (free)
USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection
12 Jun, 2019 | 08:25h | UTCEditorials: HIV Screening and Preexposure Prophylaxis Guidelines: Following the Evidence (free) AND New USPSTF Guidelines for HIV Screening and Preexposure Prophylaxis (PrEP): Straight A’s (free)
Evidence Report and Systematic Review: Preexposure Prophylaxis for the Prevention of HIV Infection (free)
Author Interviews: Screening for HIV infection and Use of Preexposure Prophylaxis for Prevention of HIV Infection: US Preventive Services Task Force Recommendation Statements (free audio) AND HIV Screening and Preexposure Prophylaxis Guidelines (free audio)
Commentaries: Expert Panel Recommends Wider Use Of Daily Pill To Prevent HIV Infections – NPR (free) AND HIV prevention pill recommended for healthy people at risk – Reuters (free)
Related: British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject)
Meta-Analyses: Dietary Glycemic Index and Load and the Risk of Type 2 Diabetes
12 Jun, 2019 | 05:40h | UTC
Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals
12 Jun, 2019 | 08:23h | UTCCommentaries: Almost 400 medical practices found ineffective in analysis of 3,000 studies – eLIFE (free) AND Hundreds of current medical practices may be ineffective – Medical News Today (free)
Related Commentary on Twitter
A review of more than 3,000 randomized clinical trials in NEJM, Lancet and JAMA reveals 396 medical reversals (results later shown to be wrong, usually in systematic reviews). 22 studies in pulmonary diseases and 45 in critical care medicine were affected. https://t.co/uAW9r3SMJs
— CryptoMD (@ClaudiaCDobler) June 11, 2019
Study Shows the Adverse Physiological Effects of Bolus Fluid Resuscitation in Children with Sepsis
12 Jun, 2019 | 08:22h | UTCCommentaries: Adverse effects of bolus fluid resuscitation—short-term benefit but long-term harm – The Lancet Respiratory Medicine (free) AND Doctors urge hospitals to reconsider the type of fluids used to treat children with sepsis – News Medical (free)
Original article: Mortality after Fluid Bolus in African Children with Severe Infection – New England Journal of Medicine (free)
Related: Implications for paediatric shock management in resource-limited settings: a perspective from the FEAST trial – Critical Care (free)
Cancer Treatment and Survivorship Statistics, 2019
12 Jun, 2019 | 05:38h | UTCCancer treatment and survivorship statistics, 2019 – CA: A Cancer Journal for Clinicians (free)
Commentaries: Cancer survivors to reach 22 million by 2030 – UPI (free) AND Cancer survivors predicted to number over 22 million by 2030 – American Cancer Society (free)
The Current and Future Global Distribution and Population at Risk of Dengue
12 Jun, 2019 | 05:39h | UTCThe current and future global distribution and population at risk of dengue – Nature Microbiology (free)
Commentaries: More than six billion people at risk of dengue fever by 2080 – London School of Hygiene & Tropical Medicine (free) AND A new picture of dengue’s growing threat – Institute for Health Metrics and Evaluation (free) AND How Dengue, a Deadly Mosquito-Borne
Disease, Could Spread in a Warming World – The New York Times (10 articles per month are free)
Related Commentary on Twitter
New #NTDs research:
current & future global distribution and population at risk of #denguehttps://t.co/Y6J6FmM2X1Projections for 2020, 2050 2080 show expansion due to climatic change & urbanisation @OliverBrady1 @lshtm @NatureMicrobiol @MOUGK @simonihay @RCReinerJr @IHME_UW pic.twitter.com/DnJCaLK6gY
— LondonNTDResearch (@NTDResearch) June 11, 2019