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Could Antibiotics Be A Silver Bullet for Kids In Africa?

17 Jun, 2019 | 06:05h | UTC

Could Antibiotics Be A Silver Bullet For Kids In Africa? – NPR (free)

Original Study: Longer-Term Assessment of Azithromycin for Reducing Childhood Mortality in Africa (free)

 


[Abstract Only] Incidence of Cosmetic-Related Injuries in Children Treated in Emergency Departments

18 Jun, 2019 | 06:37h | UTC

Cosmetic-Related Injuries Treated in US Emergency Departments: 2002 to 2016 – Clinical Pediatrics (link to abstract – $ for full-text)

Commentaries: Personal care products send a child to the emergency room every two hours – Nationwide Children’s Hospital (free) AND Keep Your Up Cosmetics and Out of Sight of of Kids – MedicalResearch.com (free)

 


Update Breast Cancer 2019 Part 3 – Current Developments in Early Breast Cancer: Review and Critical Assessment by an International Expert Panel

17 Jun, 2019 | 06:00h | UTC

Update Breast Cancer 2019 Part 3 – Current Developments in Early Breast Cancer: Review and Critical Assessment by an International Expert Panel – Geburtshilfe und Frauenheilkunde (free)

See also: Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) – Part 1 with Recommendations for the Screening, Diagnosis and Therapy of Breast Cancer (free) AND Update Breast Cancer 2019 Part 2 – Implementation of Novel Diagnostics and Therapeutics in Advanced Breast Cancer Patients in Clinical Practice (free)

 


Meta-analysis: Prophylactic and Therapeutic Effects of Honey on Radiochemotherapy-induced Mucositis

17 Jun, 2019 | 05:57h | UTC

Prophylactic and therapeutic effects of honey on radiochemotherapy-induced mucositis: a meta-analysis of randomized controlled trials – Supportive Care in Cancer (free)

 


ESGO–EFC Position Paper: Human Papillomavirus Vaccination

17 Jun, 2019 | 06:04h | UTC

Human papillomavirus vaccination: The ESGO–EFC position paper of the European society of Gynaecologic Oncology and the European Federation for colposcopy – European Journal of Cancer (free)

Commentary: European organizations strongly in favor of gender-neutral HPV vaccination – Univadis (free registration required)

 


Mon June 17 – 10 Stories of The Day!

17 Jun, 2019 | 01:57h | UTC

 

1 – Revision of expert panel’s guidelines on postoperative pain management – Anaesthesia Critical Care & Pain Medicine (free)

 

2 – Blood pressure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)

 

3 – Important Safety Alert Regarding Use of Fecal Microbiota for Transplantation and Risk of Serious Adverse Reactions Due to Transmission of Multi-Drug Resistant Organisms – U.S. Food & Drug Administration (free)

Commentaries: Fecal Transplant Is Linked to a Patient’s Death, the F.D.A. Warns – The New York Times (10 articles per month are free) AND This Poop Transplant Resulted In A Death, FDA Warning – Forbes (free) AND Be Careful Of Fecal Transplants, Warns FDA, After Patient Death – NPR (free) AND FDA issues alert after fecal microbiota transplant death – CIDRAP (free)

 

4 – Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”

 

5 – Adenosine Deaminase Diagnostic Testing in Pericardial Fluid – JAMA (free for a limited period)

 

6 – Comparison of the accuracy of human readers versus machine-learning algorithms for pigmented skin lesion classification: an open, web-based, international, diagnostic study – The Lancet Oncology (link to abstract- $ for full-text)

Commentary: Artificial intelligence for the diagnosis of skin lesions is superior to humans – Medical University of Vienna (free)

 

7 – Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis – New England Journal of Medicine (link to abstract  $ for full-text)

Commentaries: Metagenomic Sequencing Enhanced Diagnosis of Meningitis and Encephalitis Infections – MedicalResearch.com (free) AND Superfast gene sequencing helps diagnose critically ill patients – University of California – San Francisco (free) AND Rapid DNA analysis helps diagnose mystery diseases – The Conversation (free)

 

8 – Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer – Journal of the American College of Cardiology (free for a limited period)

Commentaries: Radiation treatment increases cardiac risk for lung cancer patients – Brigham and Women’s Hospital (free) AND Study: Radiation drives up cardiac event risk for lung cancer patients – UPI (free) AND Cardiac Radiation Can Increase Mortality in Lung Cancer Patients – MedicalResearch.com (free)

 

9 – 6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial – The Lancet (free)

Commentaries: Is the duration of adjuvant trastuzumab debate still clinically relevant? – The Lancet (free) AND 6 months treatment with Herceptin is as good as 12 months for preventing breast cancer return – University of Warwick (free)

 

10 – ASIPP Guidelines for Sedation and Fasting Status of Patients Undergoing Interventional Pain Management Procedures – Pain Physician (free PDF)

Related Guidelines: Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration (free) AND Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology (free)

Related Narrative Review: Nothing by Mouth at Midnight: Saving or Starving? A Literature Review – Gastroenterology Nursing (free)

“Based on extensive literature and consensus, a minimum fasting period is established as 2 hours before a procedure for clear liquids and 4 hours before procedure for light meals, rather than having all patients fast for 8 hours or even fasting beginning at midnight the night before the procedure.”

 


2019 Japanese Guidelines for the Treatment of Colorectal Cancer

17 Jun, 2019 | 06:02h | UTC

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer – International Journal of Clinical Oncology (free)

 


Recent Advances in Spontaneous Intracerebral Hemorrhage

17 Jun, 2019 | 05:40h | UTC

Recent advances in spontaneous intracerebral hemorrhage – F1000Research (free)

 


Review: IgG4-related Kidney Disease and Retroperitoneal Fibrosis

17 Jun, 2019 | 05:51h | UTC

IgG4-related kidney disease and retroperitoneal fibrosis: An update – Modern Rheumatology (free)

 


FDA Safety Alert: Fecal Transplant May Have Caused a Patient’s Death Due to Transmission of a Multi-Drug Resistant Organism

17 Jun, 2019 | 01:48h | UTC

Important Safety Alert Regarding Use of Fecal Microbiota for Transplantation and Risk of Serious Adverse Reactions Due to Transmission of Multi-Drug Resistant Organisms – U.S. Food & Drug Administration (free)

Commentaries: Fecal Transplant Is Linked to a Patient’s Death, the F.D.A. Warns – The New York Times (10 articles per month are free) AND This Poop Transplant Resulted In A Death, FDA Warning – Forbes (free) AND Be Careful Of Fecal Transplants, Warns FDA, After Patient Death – NPR (free) AND FDA issues alert after fecal microbiota transplant death – CIDRAP (free)

 


Blood Pressure in Chronic Kidney Disease: Conclusions from a KDIGO Controversies Conference

17 Jun, 2019 | 01:50h | UTC

Blood pressure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)

 


Meta-Analysis: Safety and Efficacy of Aspirin for Primary Prevention of Cancer

17 Jun, 2019 | 01:44h | UTC

Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”

 


Revision of Expert Panel’s Guidelines on Postoperative Pain Management

17 Jun, 2019 | 01:53h | UTC

Revision of expert panel’s guidelines on postoperative pain management – Anaesthesia Critical Care & Pain Medicine (free)

 


Review: Adenosine Deaminase Diagnostic Testing in Pericardial Fluid

17 Jun, 2019 | 01:40h | UTC

Adenosine Deaminase Diagnostic Testing in Pericardial Fluid – JAMA (free for a limited period)

 


[Abstract Only] Artificial Intelligence Algorithms vs. Human Readers for Diagnosis of Pigmented Skin Lesions

17 Jun, 2019 | 01:38h | UTC

Comparison of the accuracy of human readers versus machine-learning algorithms for pigmented skin lesion classification: an open, web-based, international, diagnostic study – The Lancet Oncology (link to abstract- $ for full-text)

Commentary: Artificial intelligence for the diagnosis of skin lesions is superior to humans – Medical University of Vienna (free)

 


[Abstract Only] Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis

17 Jun, 2019 | 01:35h | UTC

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis – New England Journal of Medicine (link to abstract  $ for full-text)

Commentaries: Metagenomic Sequencing Enhanced Diagnosis of Meningitis and Encephalitis Infections – MedicalResearch.com (free) AND Superfast gene sequencing helps diagnose critically ill patients – University of California – San Francisco (free) AND Rapid DNA analysis helps diagnose mystery diseases – The Conversation (free)

 


Randomized Trial: Trastuzumab for 6 Months as Good as Treatment for 12 Months in Patients with HER2-positive Early Breast Cancer

17 Jun, 2019 | 01:30h | UTC

6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial – The Lancet (free)

Commentaries: Is the duration of adjuvant trastuzumab debate still clinically relevant? – The Lancet (free) AND 6 months treatment with Herceptin is as good as 12 months for preventing breast cancer return – University of Warwick (free)

 


Cohort Study: Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients with Lung Cancer

17 Jun, 2019 | 01:32h | UTC

Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer – Journal of the American College of Cardiology (free for a limited period)

Commentaries: Radiation treatment increases cardiac risk for lung cancer patients – Brigham and Women’s Hospital (free) AND Study: Radiation drives up cardiac event risk for lung cancer patients – UPI (free) AND Cardiac Radiation Can Increase Mortality in Lung Cancer Patients – MedicalResearch.com (free)

 


ASIPP Guidelines for Sedation and Fasting Status of Patients Undergoing Interventional Pain Management Procedures

17 Jun, 2019 | 01:27h | UTC

ASIPP Guidelines for Sedation and Fasting Status of Patients Undergoing Interventional Pain Management Procedures – Pain Physician (free PDF)

Related Guidelines: Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration (free) AND Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology (free)

Related Narrative Review: Nothing by Mouth at Midnight: Saving or Starving? A Literature Review – Gastroenterology Nursing (free)

“Based on extensive literature and consensus, a minimum fasting period is established as 2 hours before a procedure for clear liquids and 4 hours before procedure for light meals, rather than having all patients fast for 8 hours or even fasting beginning at midnight the night before the procedure.”

 


2019 WSES guidelines for the Management of Severe Acute Pancreatitis

14 Jun, 2019 | 07:05h | UTC

2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free)

Related Guidelines: American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)

 


Guideline: Management of Acute Respiratory Distress Syndrome

14 Jun, 2019 | 06:57h | UTC

Formal guidelines: management of acute respiratory distress syndrome – Annals of Intensive Care (free)

Related: Guidelines on the Management of Acute Respiratory Distress Syndrome (free guidelines and reviews on the subject)

 


Fri June 14 – 10 Stories of The Day!

14 Jun, 2019 | 07:27h | UTC

 

1 – 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free)

Related Guidelines: American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)

 

2 – Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium – Clinical and Applied Thrombosis/Hemostasis (free)

Related Guidelines: BTS Guideline: Outpatient Management of Pulmonary Embolism (free) AND ACEP Clinical Policy: Evaluation and Management of Suspected Acute Venous Thromboembolism (free) AND Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians (free) AND 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) (free)

 

3 – Formal guidelines: management of acute respiratory distress syndrome – Annals of Intensive Care (free)

Related: Guidelines on the Management of Acute Respiratory Distress Syndrome (free guidelines and reviews on the subject)

 

4 – Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology – 2019 – Arquivos Brasileiros de Cardiologia (free PDF)

 

5 – Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation – CREDENCE – American College of Cardiology (free)

 

6 – Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs – Neurology (link to abstract – $ for full-text)

Commentaries: Epilepsy drugs linked to higher risk of birth defects, study says – CNN (free) AND Study Confirms Teratogenicity of Valproic Acid, Topiramate – MPR (free)

Related: Guideline: Valproate Use in Women and Girls Of Childbearing Years (free) AND Research: Topiramate Use Early in Pregnancy and the Risk of Oral Clefts (free)

 

7 – Higher doses of antidepressants “not optimal”, according to new review – The Mental Elf (free)

Original Article: Meta-analysis: Optimal Dose of Antidepressants in Major Depression (free study and commentaries)

 

8 – Influenza virus-related critical illness: prevention, diagnosis, treatment – Critical Care (free)

 

9 – Current guidelines on the management of gestational diabetes mellitus: a content analysis and appraisal – BMC Pregnancy and Childbirth (free)

 

10 – Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort study in Sweden – The BMJ (free)

Editorial: Gabapentinoids linked to new risks, including suicidal behavior (free)

Commentaries: Epilepsy drugs linked to increased risk of suicidal behavior, particularly in young people – The BMJ (free) AND Expert reaction to study on gabapentinoids and risk of suicidal behavior – Science Media Centre (free)

 


[Abstract Only] Randomized Trial: SGLT2 Inhibitor Reduces Adverse Renal Events in Patients with Type 2 Diabetes and Nephropathy

14 Jun, 2019 | 06:49h | UTC

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation – CREDENCE – American College of Cardiology (free)

 


Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology

14 Jun, 2019 | 06:53h | UTC

Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology – 2019 – Arquivos Brasileiros de Cardiologia (free PDF)

 


Consensus: Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism

14 Jun, 2019 | 07:03h | UTC

Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium – Clinical and Applied Thrombosis/Hemostasis (free)

Related Guidelines: BTS Guideline: Outpatient Management of Pulmonary Embolism (free) AND ACEP Clinical Policy: Evaluation and Management of Suspected Acute Venous Thromboembolism (free) AND Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians (free) AND 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) (free)

 


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