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M-A | Cardioprotective effects of influenza vaccination in patients with high risk of cardiovascular disease.

25 Nov, 2022 | 12:47h | UTC

Cardioprotective effects of influenza vaccination among patients with established cardiovascular disease or at high cardiovascular risk: a systematic review and meta-analysis – European Journal of Preventive Cardiology (free for a limited period)

Related:

RCT | Influenza vaccine to reduce adverse vascular events in patients with heart failure.

RCT | A double-dose influenza vaccination during hospitalization for acute coronary syndrome did not improve outcomes compared to standard-dose outpatient vaccination.

 


2ry analysis of a RCT | Decongestion with acetazolamide in acute heart failure across the spectrum of left ventricular EF.

25 Nov, 2022 | 12:45h | UTC

Decongestion with Acetazolamide in Acute Decompensated Heart Failure across the Spectrum of Left Ventricular Ejection Fraction: a Pre-specified Analysis from the ADVOR trial – Circulation

Original Study: RCT | Acetazolamide resulted in faster decongestion in patients with acute decompensated heart failure with volume overload.

 

Commentary on Twitter

 


Study shows there is substantial monkeypox transmission before symptoms appear.

25 Nov, 2022 | 12:43h | UTC

Transmission dynamics of monkeypox in the United Kingdom: contact tracing study – The BMJ

Editorial: The dynamics of monkeypox transmission – The BMJ

News Release: Evidence for “substantial” monkeypox transmission before symptoms – BMJ Newsroom

Commentaries:

Expert reaction to study looking at monkeypox transmission before symptoms appear – Science Media Centre

Study finds evidence of ‘considerable’ presymptomatic spread of monkeypox – The Guardian

 


Case–control study | GLP-1 receptor agonists linked to increased risk of thyroid cancer.

25 Nov, 2022 | 12:42h | UTC

GLP-1 Receptor Agonists and the Risk of Thyroid Cancer – Diabetes Care (link to abstract – $ for full-text)

Commentary: GLP-1 receptor agonists associated with thyroid cancer – ACP Internist

 


RCT | Vitamin D fails to prevent statin-associated muscle symptoms among new statin users.

25 Nov, 2022 | 12:40h | UTC

Statin-Associated Muscle Symptoms Among New Statin Users Randomly Assigned to Vitamin D or Placebo – JAMA Cardiology (free for a limited period)

Commentary: Vitamin D fails to reduce statin-associated muscle pain – Northwestern University

 

Commentary on Twitter

 


RT | Routine early arthroscopic partial meniscectomy is not superior to physical therapy for traumatic meniscal tears.

25 Nov, 2022 | 12:38h | UTC

Arthroscopic partial meniscectomy versus physical therapy for traumatic meniscal tears in a young study population: a randomised controlled trial – British Journal of Sports Medicine

Commentary: Arthroscopic Partial Meniscectomy vs Physical Therapy for Traumatic Meniscal Tears in a Young Study Population: what does a recent RCT show? – BJSM Blog

 

Commentary on Twitter

 


SR | Strategies to prevent and manage running-related knee injuries.

25 Nov, 2022 | 12:37h | UTC

Strategies to prevent and manage running-related knee injuries: a systematic review of randomised controlled trials – British Journal of Sports Medicine (link to abstract – $ for full-text)

Commentaries:

How can we prevent and manage running-related knee injuries? – BJSM Blog

Changes in technique, footwear and intervention prevent running-related knee injuries – Physician’s weekly

 

Commentary from the author on Twitter

 


BMJ Investigation | FDA oversight of clinical trials is “grossly inadequate,” say experts.

25 Nov, 2022 | 12:35h | UTC

FDA oversight of clinical trials is “grossly inadequate,” say experts – The BMJ

News Release: Investigation raises concerns about poor FDA oversight of clinical trials – BMJ Newsroom

Commentary: FDA Oversight of Clinical Trials Described as ‘Grossly Inadequate’ – HealthDay

 


M-A | Safety and efficacy of extracorporeal shock wave lithotripsy vs. flexible ureteroscopy in the treatment of urinary calculi.

25 Nov, 2022 | 12:33h | UTC

Safety and efficacy of extracorporeal shock wave lithotripsy vs. flexible ureteroscopy in the treatment of urinary calculi: A systematic review and meta-analysis – Frontiers in Surgery

 


Brief Review | Lung-protective sedation: moving toward a new paradigm of precision sedation.

25 Nov, 2022 | 12:32h | UTC

Lung-protective sedation: moving toward a new paradigm of precision sedation – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Brief Review | Extubation in neurocritical care patients: lesson learned.

25 Nov, 2022 | 12:31h | UTC

Extubation in neurocritical care patients: lesson learned – Intensive Care Medicine

 

Commentary on Twitter

 


RCT | Opioid-reduced anesthesia based on esketamine in gynecological day surgery.

25 Nov, 2022 | 12:29h | UTC

Opioid-reduced anesthesia based on esketamine in gynecological day surgery: a randomized double-blind controlled study – BMC Anesthesiology

 


Towards zero carbon healthcare: anesthesia.

25 Nov, 2022 | 12:28h | UTC

Towards zero carbon healthcare: anaesthesia – The BMJ

Related:

Action guidance for addressing pollution from inhalational anaesthetics – Anaesthesia

Inhaled anaesthesia and analgesia contribute to climate change – The BMJ

Carbon Footprint of General, Regional, and Combined Anesthesia for Total Knee Replacements – Anesthesia

Principles of environmentally-sustainable anaesthesia: a global consensus statement from the World Federation of Societies of Anaesthesiologists – Anaesthesia

Environmental and Occupational Considerations of Anesthesia: A Narrative Review and Update – Anesthesia & Analgesia

Working Toward the Triple Bottom Line in Surgery – NEJM Catalyst

Effects Of Surgery On A Warming Planet: Can Anesthesia Go Green? – NPR

Anaesthetic gases, climate change, and sustainable practice – The Lancet Planetary Health

Greenhouse gases: the choice of volatile anesthetic does matter – Canadian Journal of Anesthesiology

People, planet and profits: the case for greening operating rooms – Canadian Medical Association Journal

 

Commentary on Twitter

 


Retrospective Cohort Study | Comparative analysis of all-terrain vehicles, motorcycle and automobile-related trauma in a rural community.

25 Nov, 2022 | 12:27h | UTC

Comparative analysis of all-terrain vehicles, motorcycle and automobile-related trauma in a rural border community of the USA – BMJ Open

Commentaries:

Children very vulnerable to severe injury from quad bike use – BMJ Open

More Male, Pediatric Patients Suffer ATV-Related Injury – HealthDay

Related: AAP Recommendations | Prevention of pediatric all-terrain vehicles related deaths and injuries.

 

Commentary on Twitter

 


Post-trial follow-up | OS with daratumumab, bortezomib, and dexamethasone in previously treated multiple myeloma.

25 Nov, 2022 | 12:25h | UTC

Overall Survival With Daratumumab, Bortezomib, and Dexamethasone in Previously Treated Multiple Myeloma (CASTOR): A Randomized, Open-Label, Phase III Trial – Journal of Clinical Oncology

Original Study: Daratumumab, Bortezomib, and Dexamethasone for Multiple Myeloma – New England Journal of Medicine

 


Cohort Study | Association of obesity with disease outcomes in multiple sclerosis.

25 Nov, 2022 | 12:24h | UTC

Association of obesity with disease outcome in multiple sclerosis – Journal of Neurology, Neurosurgery & Psychiatry

News Release: Obesity at MS diagnosis linked to higher levels of disability – BMJ Newsroom

 


Cohort Study | Development of interstitial lung disease among patients with atrial fibrillation receiving oral anticoagulants.

25 Nov, 2022 | 12:23h | UTC

Development of Interstitial Lung Disease Among Patients With Atrial Fibrillation Receiving Oral Anticoagulants in Taiwan – JAMA Network Open

Commentaries:

Interstitial Lung Disease With Non–Vitamin K Oral Anticoagulants—A Clinical Concern? – JAMA Network Open

Slight Risk of Interstitial Lung Disease Seen With Certain DOACs – TCTMD

 


Brief Review | Core outcome sets in medical research.

25 Nov, 2022 | 12:22h | UTC

Core outcome sets in medical research – BMJ Medicine

 

Commentary on Twitter

 


Review | Obesity as a risk factor for cardiac arrhythmias.

25 Nov, 2022 | 12:21h | UTC

Obesity as a risk factor for cardiac arrhythmias – BMJ Medicine

 

Commentary on Twitter

 


Review | Exertional heat stroke: pathophysiology and risk factors.

25 Nov, 2022 | 12:19h | UTC

Exertional heat stroke: pathophysiology and risk factors – BMJ Medicine

Related:

Classic and exertional heatstroke – Nature Reviews Disease Primers

Heat-Related Illness in Emergency and Critical Care: Recommendations for Recognition and Management with Medico-Legal Considerations – Biomedicines

Treatment and Prevention of Heat-Related Illness – New England Journal of Medicine

Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Heat Illness: 2019 Update

ACSM Expert Consensus Statement on Exertional Heat Illness: Recognition, Management, and Return to Activity

 

Commentary on Twitter

 

 


Clinical questions in primary care: where to find the answers – A cross-sectional study.

25 Nov, 2022 | 12:17h | UTC

Clinical questions in primary care: Where to find the answers – a cross-sectional study – PLOS One

 


M-A | Risk of cardiovascular diseases associated with medications used in ADHD.

25 Nov, 2022 | 12:16h | UTC

Risk of Cardiovascular Diseases Associated With Medications Used in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis – JAMA Network Open

Commentaries: 

Paying Attention to Attention-Deficit/Hyperactivity Disorder Medications and Cardiovascular Risk – JAMA Network Open

Meta-Analysis Finds ADHD Drugs Not Linked To Risk Of Cardiovascular Disease – Reporter Health

 


WHO updates recommendations to guide family planning decisions.

24 Nov, 2022 | 13:38h | UTC

News Release: WHO updates recommendations to guide family planning decisions – World Health Organization

Family planning: A global handbook for providers – World Health Organization (PDF)

 

Commentary on Twitter (thread – click for more)

 


WHO report highlights oral health neglect affecting nearly half of the world’s population.

24 Nov, 2022 | 13:36h | UTC

News Release: WHO highlights oral health neglect affecting nearly half of the world’s population – World Health Organization

Report: Global oral health status report: towards universal health coverage for oral health by 2030 – World Health Organization

Commentary: Oral Health Neglect: The Overlooked Crisis Affecting 3.5 Billion People – Health Policy Watch

 

Commentary on Twitter (thread – click for more)

 


RCT | Anticoagulation for 3 months reduces recurrence rates vs. treatment for 6 weeks in patients with isolated distal DVT.

24 Nov, 2022 | 13:34h | UTC

Rivaroxaban treatment for six weeks versus three months in patients with symptomatic isolated distal deep vein thrombosis: randomised controlled trial – The BMJ

News Release: Extending anti-clotting treatment after distal DVT reduces further clot risk – BMJ Newsroom

 


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