Mon June 17 – 10 Stories of The Day!

1 – Revision of expert panel’s guidelines on postoperative pain management – Anaesthesia Critical Care & Pain Medicine (free)

2 – Blood pressure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)

3 – Important Safety Alert Regarding Use of Fecal Microbiota for Transplantation and Risk of Serious Adverse Reactions Due to Transmission of Multi-Drug Resistant Organisms – U.S. Food & Drug Administration (free)

Commentaries: Fecal Transplant Is Linked to a Patient’s Death, the F.D.A. Warns – The New York Times (10 articles per month are free) AND This Poop Transplant Resulted In A Death, FDA Warning – Forbes (free) AND Be Careful Of Fecal Transplants, Warns FDA, After Patient Death – NPR (free) AND FDA issues alert after fecal microbiota transplant death – CIDRAP (free)

4 – Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”

5 – Adenosine Deaminase Diagnostic Testing in Pericardial Fluid – JAMA (free for a limited period)

6 – Comparison of the accuracy of human readers versus machine-learning algorithms for pigmented skin lesion classification: an open, web-based, international, diagnostic study – The Lancet Oncology (link to abstract- $ for full-text)

Commentary: Artificial intelligence for the diagnosis of skin lesions is superior to humans – Medical University of Vienna (free)

7 – Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis – New England Journal of Medicine (link to abstract  $ for full-text)

Commentaries: Metagenomic Sequencing Enhanced Diagnosis of Meningitis and Encephalitis Infections – MedicalResearch.com (free) AND Superfast gene sequencing helps diagnose critically ill patients – University of California – San Francisco (free) AND Rapid DNA analysis helps diagnose mystery diseases – The Conversation (free)

8 – Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer – Journal of the American College of Cardiology (free for a limited period)

Commentaries: Radiation treatment increases cardiac risk for lung cancer patients – Brigham and Women’s Hospital (free) AND Study: Radiation drives up cardiac event risk for lung cancer patients – UPI (free) AND Cardiac Radiation Can Increase Mortality in Lung Cancer Patients – MedicalResearch.com (free)

9 – 6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial – The Lancet (free)

Commentaries: Is the duration of adjuvant trastuzumab debate still clinically relevant? – The Lancet (free) AND 6 months treatment with Herceptin is as good as 12 months for preventing breast cancer return – University of Warwick (free)

10 – ASIPP Guidelines for Sedation and Fasting Status of Patients Undergoing Interventional Pain Management Procedures – Pain Physician (free PDF)

Related Guidelines: Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration (free) AND Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology (free)

Related Narrative Review: Nothing by Mouth at Midnight: Saving or Starving? A Literature Review – Gastroenterology Nursing (free)

“Based on extensive literature and consensus, a minimum fasting period is established as 2 hours before a procedure for clear liquids and 4 hours before procedure for light meals, rather than having all patients fast for 8 hours or even fasting beginning at midnight the night before the procedure.”