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[Abstract Only] Aspirin for Primary Prevention of CV Events

12 Jun, 2019 | 05:28h | UTC

Aspirin for Primary Prevention of CV Events – American College of Cardiology (free)

Original Article: Aspirin for Primary Prevention of Cardiovascular Events – Journal of the American College of Cardiology (free)

Related: Aspirin for Primary Prevention: Is This the End of the Road? (selection of resources on the subject)

 


Tue June 11 – 10 Stories of The Day!

11 Jun, 2019 | 03:42h | UTC

 

1 – Three Public Health Interventions Could Save 94 Million Lives in 25 Years Global Impact Assessment Analysis – Circulation (free PDF)

Commentaries: Three public health interventions could prevent 94 million premature deaths – Harvard T.H. Chan School of Public Health (free) AND 3 simple steps could save 94 million lives – American Heart Association News (free) AND Lowering blood pressure, sodium intake may prevent 94 million early deaths – UPI (free)

 

2 – Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: People with Untreated “White Coat Hypertension” Twice as Likely to Die from Heart Disease – Penn Medicine (free) AND Untreated white-coat hypertension associated with increased cardiovascular and mortality risk – ACP Internist (free) AND Patients whose blood pressure only spikes at the doctor’s office are twice as likely to die of a heart attack or other cardiac event – STAT (free)

 

3 – Top 10 medical myths, busted – ACP Internist (free)

“Ten medical myths persist despite all the evidence.”

 

4 – Incidence of Herpes Zoster Among Children: 2003–2014 – Pediatrics (link to abstract – $ for full-text)

Commentaries: When kids are vaccinated against chickenpox, they’re less likely to get shingles, too – STAT (free) AND Decline in pediatric herpes zoster associated with varicella vaccine – 2 Minute Medicine (free)

 

5 – Editorial: ICD 11 – The Lancet (free)

Related: WHO: ICD-11 is Here! (free resources)

 

6 – Perspective: The war to free science – Vox (free)

Related: Plan S: Making Full and Immediate Open Access a Reality (free resources) AND Open Access 2018: A Year of Funders and Universities Drawing Lines in the Sand (free resources)

“How librarians, pirates, and funders are liberating the world’s academic research from paywalls.”

 

7 – Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Dulaglutide Cuts Cardiovascular Risk in Type 2 Diabetes – NEJM Journal Watch (free)

During a median follow-up of 5.4 years, the primary outcome (a composite endpoint of non-fatal myocardial infarction, non-fatal stroke, or death from cardiovascular causes) occurred in 12.0% of participants in the dulaglutide group and in 13.4% of participants in the placebo group (incidence rate of 2.4 per 100 person-years vs 2.7 per 100 person-years in the placebo group).

 

8 – Effect of a Self-management Support Intervention on Asthma Outcomes in Older Adults: The SAMBA Study Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentary: Study reports asthma control in older patients and shows lower ED visits – The Mount Sinai Hospital (free)

 

9 – Risk of Hospitalization for Serious Adverse Gastrointestinal Events Associated With Sodium Polystyrene Sulfonate Use in Patients of Advanced Age – JAMA Internal Medicine (free for a limited period)

Editorial: Sodium Polystyrene Sulfonate for Hyperkalemia (free)

Commentary: Sodium Polystyrene Sulfonate Tied to Increased Risk for Serious GI Events in Seniors – NEJM Journal Watch (free)

 

10 – Association of Exposure to Artificial Light at Night While Sleeping With Risk of Obesity in Women – JAMA Internal Medicine (free for a limited period)

Commentaries: Sleeping with artificial light at night associated with weight gain in women – NIH News Releases (free) AND Sleeping with lights or TV on tied to obesity – Reuters (free) AND Sleeping with the TV on may make you gain weight – Associated Press (free)

 


[Abstract Only] Early Acid Suppression Therapy Exposure and Fracture Risk in Young Children

12 Jun, 2019 | 05:18h | UTC

Early Acid Suppression Therapy Exposure and Fracture in Young Children – Pediatrics (link to abstract – $ for full-text)

Commentary: Early exposure to antacids could put infants at risk for bone fractures during childhood – News Medical (free)

 


[Abstract Only] Meta-analysis: Cardiovascular Events and Mortality in White Coat Hypertension

11 Jun, 2019 | 03:33h | UTC

Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: People with Untreated “White Coat Hypertension” Twice as Likely to Die from Heart Disease – Penn Medicine (free) AND Untreated white-coat hypertension associated with increased cardiovascular and mortality risk – ACP Internist (free) AND Patients whose blood pressure only spikes at the doctor’s office are twice as likely to die of a heart attack or other cardiac event – STAT (free)

 


[Abstract Only] Study: Varicella Vaccination Associated with Reduced Incidence of Pediatric Herpes Zoster

11 Jun, 2019 | 03:22h | UTC

Incidence of Herpes Zoster Among Children: 2003–2014 – Pediatrics (link to abstract – $ for full-text)

Commentaries: When kids are vaccinated against chickenpox, they’re less likely to get shingles, too – STAT (free) AND Decline in pediatric herpes zoster associated with varicella vaccine – 2 Minute Medicine (free)

 


Study: Three Public Health Interventions Could Save 94 Million Lives in 25 Years

11 Jun, 2019 | 03:40h | UTC

Three Public Health Interventions Could Save 94 Million Lives in 25 Years Global Impact Assessment Analysis – Circulation (free PDF)

Commentaries: Three public health interventions could prevent 94 million premature deaths – Harvard T.H. Chan School of Public Health (free) AND 3 simple steps could save 94 million lives – American Heart Association News (free) AND Lowering blood pressure, sodium intake may prevent 94 million early deaths – UPI (free)

 


Top 10 Medical Myths, Busted

11 Jun, 2019 | 03:31h | UTC

Top 10 medical myths, busted – ACP Internist (free)

“Ten medical myths persist despite all the evidence.”

 


Editorial: ICD 11

11 Jun, 2019 | 03:13h | UTC

ICD 11 – The Lancet (free)

Related: WHO: ICD-11 is Here! (free resources)

 


[Abstract Only] Randomized Trial: GLP-1 Receptor Agonist and Cardiovascular Outcomes in Type 2 Diabetes

11 Jun, 2019 | 03:01h | UTC

Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Dulaglutide Cuts Cardiovascular Risk in Type 2 Diabetes – NEJM Journal Watch (free)

During a median follow-up of 5.4 years, the primary outcome (a composite endpoint of non-fatal myocardial infarction, non-fatal stroke, or death from cardiovascular causes) occurred in 12.0% of participants in the dulaglutide group and in 13.4% of participants in the placebo group (incidence rate of 2.4 per 100 person-years vs 2.7 per 100 person-years in the placebo group).

 


Perspective: The War to Free Science

11 Jun, 2019 | 03:11h | UTC

The war to free science – Vox (free)

Related: Plan S: Making Full and Immediate Open Access a Reality (free) AND Open Access 2018: A Year of Funders and Universities Drawing Lines in the Sand (free)

“How librarians, pirates, and funders are liberating the world’s academic research from paywalls.”

 


Risk of Hospitalization for Serious Adverse Gastrointestinal Events Associated with Sodium Polystyrene Sulfonate

11 Jun, 2019 | 02:36h | UTC

Risk of Hospitalization for Serious Adverse Gastrointestinal Events Associated With Sodium Polystyrene Sulfonate Use in Patients of Advanced Age – JAMA Internal Medicine (free for a limited period)

Editorial: Sodium Polystyrene Sulfonate for Hyperkalemia (free)

Commentary: Sodium Polystyrene Sulfonate Tied to Increased Risk for Serious GI Events in Seniors – NEJM Journal Watch (free)

 


Randomized Trial: Self-management Support Intervention Improve Outcomes in Older Adults with Asthma

11 Jun, 2019 | 02:43h | UTC

Effect of a Self-management Support Intervention on Asthma Outcomes in Older Adults: The SAMBA Study Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentary: Study reports asthma control in older patients and shows lower ED visits – The Mount Sinai Hospital (free)

 


Cohort Study: Women Exposed to Artificial Light While Sleeping May Be at Increased Risk of Obesity

11 Jun, 2019 | 02:30h | UTC

Association of Exposure to Artificial Light at Night While Sleeping With Risk of Obesity in Women – JAMA Internal Medicine (free for a limited period)

Commentaries: Sleeping with artificial light at night associated with weight gain in women – NIH News Releases (free) AND Sleeping with lights or TV on tied to obesity – Reuters (free) AND Sleeping with the TV on may make you gain weight – Associated Press (free)

 


Consensus Recommendations: Acute-on-chronic Liver Failure

9 Jun, 2019 | 22:08h | UTC

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update – Hepatology International (free)

Related: Management of acute-on-chronic liver failure: an algorithmic approach – Hepatology International (free) AND cute-on-chronic liver failure: an update – Gut (free)

 


EULAR Recommendations for the Management of Gout

9 Jun, 2019 | 22:11h | UTC

2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free)

 


Mon June 10 – 10 Stories of The Day!

10 Jun, 2019 | 00:01h | UTC

 

1 – 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free)

 

2 – Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update – Hepatology International (free)

Related: Management of acute-on-chronic liver failure: an algorithmic approach – Hepatology International (free) AND cute-on-chronic liver failure: an update – Gut (free)

 

3 – Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis – The Lancet Psychiatry (free)

Commentaries: Which antidepressant doses are optimal? – The Lancet Psychiatry (free) AND Expert reaction to systematic review and dose-response meta-analysis of antidepressants – Science Media Centre (free)

 

4 – Vitamin D Supplementation and Prevention of Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: NIH-funded trial finds vitamin D does not prevent type 2 diabetes in people at high risk – NIH News Releases (free) AND Vitamin D fails to prevent type 2 diabetes in large study – Reuters (free) AND Vitamin D Supplements Do Not Significantly Reduce Risk of Developing Type 2 Diabetes, According to Research Presented Today at the ADA’s Scientific Sessions – American Diabetes Association (free)

 

5 – Opinion: The Business of Health Care Depends on Exploiting Doctors and Nurses – The New York Times (10 articles per month are free)

“One resource seems infinite and free: the professionalism of caregivers.”

 

6 – New preprint server for medical research – The BMJ (free)

See also: New preprint server for the health sciences announced today – Cold Spring Harbor Laboratory (CSHL) (free) AND How to bring preprints to the charged field of medicine – Nature News (free)

 

7 – Association of Net Ultrafiltration Rate With Mortality Among Critically Ill Adults With Acute Kidney Injury Receiving Continuous Venovenous Hemodiafiltration: A Secondary Analysis of the Randomized Evaluation of Normal vs Augmented Level (RENAL) of Renal Replacement Therapy Trial – JAMA Network Open (free)

Commentaries: Rapid Fluid Removal Tied to Worse Survival in ICU Patients With AKI – Renal & Urology News (free) AND Rapidly Removing Fluid from Critically Ill Patients in Kidney Failure Linked to Increased Risk of Death – University of Pittsburg (free)

 

8 – Statin Toxicity: Mechanistic Insights and Clinical Implications – Circulation Research (free)

 

9 – Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Quick Take: Individualised nutritional support in medical inpatients at nutritional risk – 2 Minute Medicine (free) AND Individual nutrition shows benefits in hospital patients – University of Basel (free)

 

10 – Aspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analyses of randomized controlled trials – Cardiovascular Diabetology (free)

Commentary: Aspirin offers benefit for primary CVD prevention in DM – Univadis (free registration required)

Related Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (free study and commentaries)

 


[Abstract Only] Vitamin D Fails to Prevent Type 2 Diabetes in Patients with Pre-diabetes

9 Jun, 2019 | 21:55h | UTC

Vitamin D Supplementation and Prevention of Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: NIH-funded trial finds vitamin D does not prevent type 2 diabetes in people at high risk – NIH News Releases (free) AND Vitamin D fails to prevent type 2 diabetes in large study – Reuters (free) AND Vitamin D Supplements Do Not Significantly Reduce Risk of Developing Type 2 Diabetes, According to Research Presented Today at the ADA’s Scientific Sessions – American Diabetes Association (free)

 


Meta-analysis: Optimal Dose of Antidepressants in Major Depression

9 Jun, 2019 | 22:07h | UTC

Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis – The Lancet Psychiatry (free)

Commentaries: Which antidepressant doses are optimal? – The Lancet Psychiatry (free) AND Expert reaction to systematic review and dose-response meta-analysis of antidepressants – Science Media Centre (free)

 


Opinion: The Business of Health Care Depends on Exploiting Doctors and Nurses

9 Jun, 2019 | 21:52h | UTC

Opinion: The Business of Health Care Depends on Exploiting Doctors and Nurses – The New York Times (10 articles per month are free)

“One resource seems infinite and free: the professionalism of caregivers.”

 


New Preprint Server for Medical Research

9 Jun, 2019 | 21:51h | UTC

New preprint server for medical research – The BMJ (free)

See also: New preprint server for the health sciences announced today – Cold Spring Harbor Laboratory (CSHL) (free) AND How to bring preprints to the charged field of medicine – Nature News (free)

 

Related Commentary on Twitter

 


Meta-analysis: Aspirin has Potential Benefits for Primary Prevention of Cardiovascular Outcomes in Diabetes

9 Jun, 2019 | 21:45h | UTC

Aspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analyses of randomized controlled trials – Cardiovascular Diabetology (free)

Commentary: Aspirin offers benefit for primary CVD prevention in DM – Univadis (free registration required)

Related Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (free study and commentaries)

 


Study: Rapid Removal of Fluid Linked to Worse Outcomes Among Critically Ill Adults With Acute Kidney Injury Receiving Continuous Venovenous Hemodiafiltration

9 Jun, 2019 | 21:49h | UTC

Association of Net Ultrafiltration Rate With Mortality Among Critically Ill Adults With Acute Kidney Injury Receiving Continuous Venovenous Hemodiafiltration: A Secondary Analysis of the Randomized Evaluation of Normal vs Augmented Level (RENAL) of Renal Replacement Therapy Trial – JAMA Network Open (free)

Commentaries: Rapid Fluid Removal Tied to Worse Survival in ICU Patients With AKI – Renal & Urology News (free) AND Rapidly Removing Fluid from Critically Ill Patients in Kidney Failure Linked to Increased Risk of Death – University of Pittsburg (free)

 


[Abstract Only] Randomized Trial: Individualized Nutritional Support in Medical Inpatients at Nutritional Risk

9 Jun, 2019 | 21:47h | UTC

Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Quick Take: Individualised nutritional support in medical inpatients at nutritional risk – 2 Minute Medicine (free) AND Individual nutrition shows benefits in hospital patients – University of Basel (free)

 


Statin Toxicity: Mechanistic Insights and Clinical Implications

9 Jun, 2019 | 21:48h | UTC

Statin Toxicity: Mechanistic Insights and Clinical Implications – Circulation Research (free)

 


Management of Congenital Heart Disease: State of the Art

9 Jun, 2019 | 19:37h | UTC

Management of Congenital Heart Disease: State of the Art – Children (free articles)

Part I—ACYANOTIC Heart Defects

Part II—Cyanotic Heart Defects

 


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