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Guideline: Prevention of Positioning Injuries During Gynecologic Surgery

25 Apr, 2021 | 20:50h | UTC

The Prevention of Positioning Injuries During Gynecologic Surgery. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry Number 015/077, October 2020) – Geburtshilfe und Frauenheilkunde

 


Guide to Enhanced Recovery for Cancer Patients Undergoing Liver Surgery

25 Apr, 2021 | 20:53h | UTC

Guide to Enhanced Recovery for Cancer Patients Undergoing Liver Surgery – Annals of Surgical Oncology

See also: Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations – World Journal of Surgery AND Enhanced Recovery After Surgery (ERAS) Society Guidelines

 


RCT: No benefit from immune checkpoint inhibitors in newly diagnosed stage III or IV ovarian cancer

25 Apr, 2021 | 20:57h | UTC

Atezolizumab, Bevacizumab, and Chemotherapy for Newly Diagnosed Stage III or IV Ovarian Cancer: Placebo-Controlled Randomized Phase III Trial (IMagyn050/GOG 3015/ENGOT-OV39) – Journal of Clinical Oncology

Editorial: Immune Checkpoint Inhibitors in Ovarian Cancer: Can We Bridge the Gap Between IMagynation and Reality?

 


Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized

23 Apr, 2021 | 08:48h | UTC

High-dimensional characterization of post-acute sequalae of COVID-19 – Nature

Commentary: Among COVID-19 survivors, an increased risk of death, serious illness – Washington University School of Medicine

 

Commentary on Twitter (thread – click for more)

 


Guideline: Diagnosis and Treatment of Endometriosis

25 Apr, 2021 | 20:46h | UTC

Diagnosis and Treatment of Endometriosis. Guideline of the DGGG, SGGG and OEGGG (S2k Level, AWMF Registry Number 015/045, August 2020) – Geburtshilfe und Frauenheilkunde

 


Recommendations on the Management of Maternal Hepatitis B, C and D Infection in Pregnancy

25 Apr, 2021 | 20:44h | UTC

Recommendations of the AGG (Task Force for Obstetrics, Section Maternal Diseases) on the Management of Maternal Hepatitis B, C and D Infection in Pregnancy – Geburtshilfe und Frauenheilkunde

 


Guideline: Vulvovaginal Candidosis (Excluding Mucocutaneous Candidosis)

25 Apr, 2021 | 20:47h | UTC

Vulvovaginal Candidosis (Excluding Mucocutaneous Candidosis): Guideline of the German (DGGG), Austrian (OEGGG) and Swiss (SGGG) Society of Gynecology and Obstetrics (S2k-Level, AWMF Registry Number 015/072, September 2020) – Geburtshilfe und Frauenheilkunde

 


NIH Updates COVID-19 Treatment Guidelines – adds recommendations on colchicine, fluvoxamine, and monoclonal antibodies

23 Apr, 2021 | 08:46h | UTC

NIH Coronavirus Disease 2019 (COVID-19)
Treatment Guidelines – National Institutes of Health

 


RCT: COVID outpatients don’t benefit from hydroxychloroquine, lopinavir-ritonavir

23 Apr, 2021 | 08:42h | UTC

COVID outpatients don’t benefit from hydroxychloroquine, lopinavir-ritonavir – CIDRAP

Original study: Effect of Early Treatment With Hydroxychloroquine or Lopinavir and Ritonavir on Risk of Hospitalization Among Patients With COVID-19: The TOGETHER Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter (thread – Click for more)

 


Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19

23 Apr, 2021 | 08:39h | UTC

Acute Ischemic Stroke During the Convalescent Phase of Asymptomatic COVID-2019 Infection in Men – JAMA Network Open

Commentary: ‘The next wave of complications’: Asymptomatic COVID-19 patients face a prolonged stroke risk – Cardiovascular Business

 

Commentary on Twitter

 


Covid-19: More data on the increased risks to pregnant women and their newborn infants

23 Apr, 2021 | 08:44h | UTC

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study – JAMA Pediatrics

Editorial: COVID-19 in Pregnant Women and Their Newborn Infants

Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN

Related: Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis

 

Commentary on Twitter

 


RCT: Single-Dose Johnson & Johnson Vaccine has 85% efficacy against severe/critical Covid-19 and maintains efficacy against variant B.1.351

22 Apr, 2021 | 08:50h | UTC

Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19 – New England Journal of Medicine

 


Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

22 Apr, 2021 | 08:49h | UTC

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons – New England Journal of Medicine

Audio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine

Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News

 


Covid-19: What do we know about airborne transmission of SARS-CoV-2?

23 Apr, 2021 | 08:33h | UTC

Covid-19: What do we know about airborne transmission of SARS-CoV-2? – The BMJ

Related: Ten scientific reasons in support of airborne transmission of SARS-CoV-2 AND Editorial: Covid-19 has redefined airborne transmission

 


COVID vaccines and kids: five questions as trials begin

23 Apr, 2021 | 08:37h | UTC

COVID vaccines and kids: five questions as trials begin – Nature

Related perspective: Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe. – Undark

 


Systematic review shows there is insufficient evidence on the best approaches to stop long‐term antidepressant use – “Future studies should distinguish carefully between relapse and withdrawal symptoms”

23 Apr, 2021 | 08:19h | UTC

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety disorders in adults – Cochrane Library

Author interview: Stopping long-term antidepressants in people with depression or anxiety – Cochrane Library

Commentary: ‘Urgent’ need for more evidence on safely stopping antidepressants, say experts – Metro

“Future studies should distinguish carefully between relapse and withdrawal symptoms and follow emerging guidance to use taper schemes of many weeks or months (or longer for long-term users) down to very low doses before stopping. Such studies would give us a clearer idea of the ability of antidepressants to prevent relapse.”

 

Commentary on Twitter (thread – click for more)

 


Viewpoint | Remote Research and Clinical Trial Integrity During and After the Coronavirus Pandemic

23 Apr, 2021 | 08:34h | UTC

Remote Research and Clinical Trial Integrity During and After the Coronavirus Pandemic – JAMA

 


AHA Scientific Statement: Obesity and Cardiovascular Disease

23 Apr, 2021 | 08:22h | UTC

Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association – Circulation

News Release: More belly weight increases danger of heart disease even if BMI does not indicate obesity – American Heart Association

Commentary: It’s time to measure your waistline, according to new recommendations. Belly fat raises your risk for disease – CNN

 


Perioperative hemodynamic optimization: from guidelines to implementation—an experts’ opinion paper

23 Apr, 2021 | 08:21h | UTC

Perioperative hemodynamic optimization: from guidelines to implementation—an experts’ opinion paper – Annals of Intensive Care

 


RCT: Treatments for vulnerable older adult women with ovarian cancer compared

23 Apr, 2021 | 08:15h | UTC

Efficacy and Safety of First-line Single-Agent Carboplatin vs Carboplatin Plus Paclitaxel for Vulnerable Older Adult Women With Ovarian Cancer: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)

Editorial: Vulnerable Older Adults With Ovarian Cancer—Time to Stop Undertreating (free for a limited period)

 


Systematic review: Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease

23 Apr, 2021 | 08:17h | UTC

Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease – Cochrane Library

Summary: Abdominal ultrasound and alpha-foetoprotein for the diagnosis of hepatocellular carcinoma – Cochrane Library

 


Systematic Review: PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer

23 Apr, 2021 | 08:16h | UTC

PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer – Cochrane Library

Summary: PARP inhibitors for locally advanced or metastatic breast cancer – Cochrane Library

 


Survey: Despite guideline recommendations, many patients with low-risk thyroid cancer continue to be treated with suppressive doses of thyroid hormone

23 Apr, 2021 | 08:13h | UTC

TSH Suppression for Papillary Thyroid Cancer: A Physician Survey Study – Thyroid (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Long-Term Cardiovascular Outcomes in Systemic Lupus Erythematosus

23 Apr, 2021 | 08:08h | UTC

Cardiovascular Outcomes in Systemic Lupus Erythematosus – American College of Cardiology

Original study: Long-Term Cardiovascular Outcomes in Systemic Lupus Erythematosus – Journal of the American College of Cardiology (link to abstract – $ for full-text)

 


Do you really need to drink 8 glasses of water a day? An exercise scientist explains why your kidneys say ‘no’

23 Apr, 2021 | 08:11h | UTC

Do you really need to drink 8 glasses of water a day? An exercise scientist explains why your kidneys say ‘no’ – The Conversation

 


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