Archives
AGA recommends intragastric balloons as an additional weight loss option for obese patients
23 Apr, 2021 | 08:10h | UTCOriginal article: AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity – Gastroenterology
General anesthesia in end‐of‐life care: extending the indications for anesthesia beyond surgery
22 Apr, 2021 | 08:26h | UTC
Commentary on Twitter
🔐"Our redefinition of the scope and reach of general anaesthesia through end‐of‐life care, radical though it is, would recognise that anaesthetists have skills that can help alleviate suffering for the dying patient."@TaklaAntony @Assoc_Anaes #FOAMed
🔗https://t.co/51Ja7lFIBU pic.twitter.com/vnpvf484my
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) April 21, 2021
New-Generation Antibiotics for Treatment of Gram-Positive Infections: A Review with Focus on Endocarditis and Osteomyelitis
23 Apr, 2021 | 08:06h | UTC
Financial Toxicity in Advanced and Metastatic Cancer: Overburdened and Underprepared
22 Apr, 2021 | 08:24h | UTCRelated: Opinion – The high price of anticancer drugs: origins, implications, barriers, solutions AND Tackling the High Cost of Cancer Care AND Study: Clinician Engagement Regarding Financial Toxicity After Diagnosis of Cancer AND
An Update on Eight “New” Antibiotics against Multidrug-Resistant Gram-Negative Bacteria
23 Apr, 2021 | 08:05h | UTC
Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery
22 Apr, 2021 | 08:28h | UTCOpportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review – JAMA Surgery (free for a limited period)
See also: Enhanced Recovery After Surgery (ERAS) Society Guidelines
Ahead of World Malaria Day, WHO launches effort to stamp out malaria in 25 more countries by 2025
22 Apr, 2021 | 08:23h | UTCReport: Zeroing in on malaria elimination: Final report of the E-2020 initiative – World Health Organization
Review: Oral Antiplatelet Therapy After Acute Coronary Syndrome
22 Apr, 2021 | 08:22h | UTCOral Antiplatelet Therapy After Acute Coronary Syndrome: A Review – JAMA (free for a limited period)
Audio Clinical Review: Dual Antiplatelet Therapy After Acute Coronary Syndrome – JAMA
Guideline: Diagnosis and Evaluation of Hypersensitivity Pneumonitis
22 Apr, 2021 | 08:21h | UTCSee also: Executive Summary
Systematic review: Venoarterial Extracorporeal Membrane Oxygenation in Massive Pulmonary Embolism-Related Cardiac Arrest
22 Apr, 2021 | 08:18h | UTCSummary: VA ECMO for Massive PE + Cardiac Arrest – Journal Feed
M-A: Aspirin alone better than dual antiplatelet therapy after transcatheter aortic valve implantation
22 Apr, 2021 | 08:20h | UTC
Vaccine Breakthrough Infections with SARS-CoV-2 Variants
22 Apr, 2021 | 08:47h | UTCVaccine Breakthrough Infections with SARS-CoV-2 Variants – New England Journal of Medicine
Commentary on Twitter
Mild #COVID19 symptoms developed in two fully vaccinated persons. Serum tests showed high titers of antibodies capable of neutralizing the wild-type strain of #SARSCoV2 first identified in Wuhan, China, but sequencing of the virus isolates revealed novel variants.
— NEJM (@NEJM) April 21, 2021
Opinion | Platform Trials — Beware the Noncomparable Control Group
22 Apr, 2021 | 08:44h | UTCPlatform Trials — Beware the Noncomparable Control Group – New England Journal of Medicine
A year in the COVID-19 vaccine scheme COVAX
22 Apr, 2021 | 08:43h | UTCA year in the COVID-19 vaccine scheme COVAX – Reuters
Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease
22 Apr, 2021 | 08:40h | UTC
Commentaries on Twitter
Early data from @RCHMelbourne show that, at 3-6 month follow-up, all 151 children with mild and asymptomatic #COVID19 had returned to their baseline health status and post-acute COVID-19 symptoms had resolved.
Letter from @Shidan_Tosif & colleagues: https://t.co/XXa0EPIgPY
— The Lancet Child & Adolescent Health (@LancetChildAdol) April 20, 2021
Given such little available data, this study from Australia on post-acute COVID-19 symptoms in children is very important
Findings are extremely reassuring
Post-acute symptoms were rare, and mild (cough 4%, fatigue 2%, cough and fatigue 1%)
Great news!https://t.co/TEJyES3Crx
— Alasdair Munro (@apsmunro) April 21, 2021
Great to see research looking at whether long Covid is a problem in children.
From this Melbourne cohort, enduring cough and fatigue are uncommon.
It hasn’t been clear to me whether borders will reopen before children are vaccinated so this is VIP https://t.co/iLXqwXJmOt
— Jin Russell (@DrJinRussell) April 21, 2021
Truly encouraging data on post-acute #COVID19 in children. Single-center in Australia. n=151.
8% post-acute symptoms – all symptomatic COVID-19.
Mild symptoms: cough 4%, fatigue 2%, both 1%. Duration: cough 3-8w; post-viral fatigue 6-8w. All solved in follow-up time 3-6 months. https://t.co/vKrEFZlw3C— Pablo Guisado Vasco (@PabloGVasco) April 21, 2021
Perspective | Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe.
22 Apr, 2021 | 08:38h | UTCDo Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe. – Undark
Commentary on Twitter
Great article by @Sara_Talpos
key qs:
1 Does a kid need to be vaccinated for their sake?
2 Does a kid need to be vaccinated to protect adults who decline?
3. Does a kid need to be vaccinated to protect adults who were vax'd?— Vinay Prasad MD MPH (@VPrasadMDMPH) April 20, 2021
India’s massive COVID surge puzzles scientists
22 Apr, 2021 | 08:36h | UTCIndia’s massive COVID surge puzzles scientists – Nature
See also: ‘The system has collapsed’: India’s descent into Covid hell – The Guardian AND India’s COVID-19 surge intensifies – CIDRAP
ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia
21 Apr, 2021 | 07:11h | UTCSee also: Diagnostic Flow Chart
Commentary on Twitter
The ISTH has released interim guidance on vaccine-induced immune thrombotic thrombocytopenia (#VITT) to inform the management of suspected thrombosis in subjects who have recently received the AstraZeneca or Johnson & Johnson vaccine. https://t.co/qqtQtpywaf pic.twitter.com/wNmjNNDs4z
— ISTH (@isth) April 20, 2021
Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions
22 Apr, 2021 | 08:19h | UTCSee also: Final Report AND Evidence Summary
How COVID hurt the fight against other dangerous diseases
22 Apr, 2021 | 08:35h | UTCHow COVID hurt the fight against other dangerous diseases – Nature
Related: World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis AND WHO: Benefits of continuing to provide life-saving HIV services outweigh the risk of COVID-19 transmission by 100 to 1
NICE Guideline | Neonatal infection: antibiotics for prevention and treatment
21 Apr, 2021 | 06:46h | UTC
Review: Long-Term Infectious Complications of Kidney Transplantation
22 Apr, 2021 | 08:16h | UTC
RCT: Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
22 Apr, 2021 | 08:15h | UTCSacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
NICE Guideline | Postnatal care
21 Apr, 2021 | 06:43h | UTCPostnatal care – National Institute for Health and Care Excellence
Cohort study: Increased bleeding risk with no therapeutic benefit with the addition of aspirin to direct oral anticoagulant therapy when there is not a clear indication
21 Apr, 2021 | 06:34h | UTCAdverse Events Associated With the Addition of Aspirin to Direct Oral Anticoagulant Therapy Without a Clear Indication – JAMA Internal Medicine (free for a limited period)
Commentaries: DOAC + Aspirin Common Without Clear Indication, Tied to More Bleeding – NEJM Journal Watch AND Many AFib patients wrongly prescribed aspirin therapy, study finds – UPI
Commentary on Twitter
Obs study in @JAMAInternalMed finds aspirin is often prescribed along w/ direct acting oral anticoagulant without clear reason and the combo *associates* w higher rates of bleeding https://t.co/nKsWtLnjr9
Good one @GBarnesMD
ASA is the number 1 drug I #deprescribe
— John Mandrola, MD (@drjohnm) April 19, 2021