Archives
Opinion | 7 reasons why we should not need boosters for COVID-19.
31 May, 2021 | 08:21h | UTC7 Reasons Why We Should Not Need Boosters for COVID-19 – by Monica Ghandi, MD
No COVID-19 cases found after a well-controlled indoor concert.
31 May, 2021 | 08:24h | UTCNo COVID-19 cases found after well-controlled indoor concert – CIDRAP
Invited Commentary: Innovations in COVID-19 testing: the road from pandemic response to control – The Lancet Infectious Diseases
Commentary on Twitter (thread – click for more)
Report of the Barcelona music event out here. These are difficult studies to do – and you need to carefully review them.
Same-day SARS-CoV-2 antigen test screening in an indoor mass-gathering live music event: a randomised controlled trial https://t.co/KDMtsGD23v
— Jon Deeks FMedSci (@deeksj) May 28, 2021
Opinion | The Covid-19 lab leak theory is a tale of weaponized uncertainty.
31 May, 2021 | 08:19h | UTCThe Covid-19 Lab Leak Theory Is a Tale of Weaponized Uncertainty – Wired
See also: Divisive COVID ‘lab leak’ debate prompts dire warnings from researchers – Nature
New IDSA Guidelines on antigen testing for the diagnosis of COVID-19.
31 May, 2021 | 08:25h | UTC
What the science says about lifting mask mandates – “Wearing masks should probably be one of the last things we stop doing”.
31 May, 2021 | 08:17h | UTCWhat the science says about lifting mask mandates – Nature
Covid-19 vaccination prevents transmission from vaccinated to unvaccinated household members.
31 May, 2021 | 08:18h | UTCThe indirect effect of mRNA-based Covid-19 vaccination on unvaccinated household members – medRxiv
Commentary on Twitter
More on less transmission, yet another incentive:
"Our results suggest that mRNA-based vaccines do not only prevent #SARSCoV2 infections among vaccinated individuals but lead to a substantial reduction in infections among unvaccinated household members"https://t.co/sIqoOLiH3b pic.twitter.com/6rv2tojR2m— Eric Topol (@EricTopol) May 29, 2021
Vietnam finds new rapidly spreading SARS-CoV-2 variant, hybrid of B.1.617.2 and B.1.1.7 strains.
31 May, 2021 | 08:16h | UTCVietnam finds new virus variant, hybrid of India, UK strains – Associated Press
See also: Covid: Vietnam detects new UK-Indian variant, health officials say – BBC AND Vietnam says new Covid variant is hybrid of India and UK strains – The Guardian
[Not published yet] Observational study in Uruguay found CoronaVac reduced mortality by 97 percent – “In people who had received two doses, it reduced infection with the coronavirus by 57 percent and intensive care admissions by 95 percent”.
31 May, 2021 | 08:14h | UTCCoronaVac reduces mortality by 97 percent: Uruguay study – Associated Press
Oxygen shortages threaten ‘total collapse’ of dozens of health systems.
31 May, 2021 | 08:12h | UTCOxygen shortages threaten ‘total collapse’ of dozens of health systems – The Guardian
Related: How covid-19 revealed the scandal of medical oxygen supplies worldwide – Nature AND COVID-19 Oxygen Needs in Low- and Middle-Income Countries Have Tripled in Just Three Months – Where are Solutions? – Health Policy Watch
Guideline | Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematologic malignancies and solid tumors.
31 May, 2021 | 08:09h | UTC
Providing more low-value care does not lead to higher patient experience ratings – “New study challenges the assumption that offering patients more tests and procedures will lead to higher patient experience ratings”.
31 May, 2021 | 08:11h | UTCOriginal Study: Association of Low-Value Care Exposure With Health Care Experience Ratings Among Patient Panels – JAMA Internal Medicine
Commentary on Twitter
New work led by @sanghavi_prachi w/ @A_Schwa & Alan Zaslavsky
We asked do PCPs w/ more wasteful practice patterns get better patient ratings?
Answer is no. No they don't
This should allay overblown concerns about pt experience measures leading us to satisfy patients to death https://t.co/cosXvLA6Ql
— Michael McWilliams (@JMichaelMcW) May 28, 2021
NICE recommends offering women induced labor earlier in new draft guidance – “women with uncomplicated singleton pregnancies should be offered induction at 41 weeks and the induction should take place as soon as possible. Previous guidelines advised induction between 41 and 42 weeks”.
31 May, 2021 | 08:08h | UTC
RCT: Among children with protracted bacterial bronchitis, a 4-week course of amoxicillin–clavulanate is not better than a 2-week course in achieving clinical cure by 28 days.
31 May, 2021 | 08:02h | UTCCommentary: Four weeks of antibiotics for kids’ chronic cough no better than 2, study finds – CIDRAP
Commentary on Twitter
NEW Research—4 weeks of amoxicillin–clavulanate for children with chronic wet cough and suspected PBB confers little advantage vs 2 weeks in achieving clinical cure by 28 days
RCT from Tom Ruffles & colleagues https://t.co/77w08dZ20z pic.twitter.com/LYgOeJbDX8
— The Lancet Respiratory Medicine (@LancetRespirMed) May 26, 2021
Observational study suggests ceftriaxone is similarly effective to benzylpenicillin for the treatment of neurosyphilis, potentially decreasing the length of hospital stay (mean 13.8 days vs. 8.9 days).
31 May, 2021 | 08:06h | UTCCeftriaxone compared with benzylpenicillin in the treatment of neurosyphilis in France: a retrospective multicentre study – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Academic bullying is too often ignored. Here are some targets’ stories.
31 May, 2021 | 07:59h | UTCAcademic bullying is too often ignored. Here are some targets’ stories – Science (a few articles per month are free)
Lab study found CoronaVac serum neutralization efficiency was significantly decreased against B.1.526, P.1, and B1.351 SARS-CoV-2 variants.
28 May, 2021 | 08:26h | UTC
COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required.
28 May, 2021 | 08:27h | UTCInvited Commentary: Exploiting an early immunological window of opportunity in COVID-19 – The Lancet Respiratory Medicine
WHO COVAX Joint Statement: Call to action to equip COVAX to deliver 2 billion doses in 2021.
28 May, 2021 | 08:28h | UTC
Commentary on Twitter (thread – click for more)
.@DrTedros, @GaviSeth, @DrRHatchett, Henrietta Fore @unicefchief issued a call to action to equip #COVAX to deliver 2 billion #COVID19 vaccine doses in 2021
👉 https://t.co/wtBaqHAoti #VaccinEquity— World Health Organization (WHO) (@WHO) May 27, 2021
The global burden of smoking tobacco and attributable disease in 204 countries and territories – “In the absence of intervention, the annual toll of 7.69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades”.
28 May, 2021 | 08:19h | UTCRelated studies: Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019 – The Lancet Public Health AND Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and initiation among young people in 204 countries and territories, 1990–2019 – The Lancet Public Health
RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site pain (in 79 to 86% of participants), fatigue (in 60 to 66%), and headache (in 55 to 65%).
28 May, 2021 | 08:24h | UTC
Commentary on Twitter
The 12-15 year-olds mRNA vaccine randomized, placebo-controlled clinical trial is published @NEJM today [@BioNTech_Group/@Pfizer]https://t.co/7GlgC9xdd0
—100% efficacy (95% CI 75,100)
—1.8 X higher levels of neutralizing antibodies than 16-25 yr olds
—very good safety profile pic.twitter.com/hQzkpuA5Nu— Eric Topol (@EricTopol) May 27, 2021
Covid-19: Pfizer-BioNTech vaccine is “likely” responsible for deaths of some elderly patients, Norwegian review finds.
28 May, 2021 | 08:22h | UTC
Commentary on Twitter
The Pfizer-BioNTech covid-19 vaccine is “likely” to have been responsible for at least 10 deaths of frail elderly people in nursing homes in Norway, an expert review concluded, although it emphasised considerable uncertainty around its conclusionshttps://t.co/w32jH6MtRH
— The BMJ (@bmj_latest) May 27, 2021
Advance Care Planning for people with dementia: recognizing moral dilemmas faced by physicians.
28 May, 2021 | 08:14h | UTC
EULAR recommendations for intra-articular therapies.
28 May, 2021 | 08:16h | UTCEULAR recommendations for intra-articular therapies – Annals of Rheumatic Diseases
Viewpoint | A population-level approach to suicide prevention.
28 May, 2021 | 08:12h | UTCA Population-Level Approach to Suicide Prevention – JAMA
Google strikes a deal with hospital chain to use 32 million patient records to develop healthcare algorithms.
28 May, 2021 | 08:10h | UTCPress release: HCA Healthcare Partners With Google Cloud to Accelerate Digital Transformation
Commentaries: Doctor Google will see you now! Privacy fears as tech giant ‘strikes deal’ with hospital chain to use 32 MILLION patient records to create algorithms that will guide healthcare workers’ decisions – The Daily Mail AND Google to use patient data to develop healthcare algorithms for hospital chain – The Verge