Archives
WHO validates Sinovac-CoronaVac COVID-19 vaccine for emergency use and issues interim policy recommendations.
2 Jun, 2021 | 08:42h | UTCCommentary: WHO grants emergency approval to 2nd Chinese COVID vaccine – MedicalXpress
Commentary on Twitter (thread – click for more)
WHO today validated the Sinovac-CoronaVac #COVID19 vaccine for emergency use, giving countries, funders, procuring agencies & communities the assurance that it meets international standards for safety, efficacy and manufacturing.
More ⬇️ https://t.co/Uy0xmGlAIT— World Health Organization (WHO) (@WHO) June 1, 2021
After COVID-19 successes, researchers push to develop mRNA vaccines for other infectious diseases and cancer.
2 Jun, 2021 | 08:34h | UTC
Review: SARS-CoV-2 variants, spike mutations and immune escape.
2 Jun, 2021 | 08:33h | UTCSARS-CoV-2 variants, spike mutations and immune escape – Nature Reviews Microbiology
Commentary on Twitter
A new, exceptional review of the #SARSCoV2 major variants, zooming in on the culprit mutations, Δ epitopes/antigens.
It concludes there is a "high probability of future mutation-mediated escape from host immunity"https://t.co/D4mFot8Ot5@NatureRevMicro @_wharvey @robertson_lab pic.twitter.com/JgzAhpsviq— Eric Topol (@EricTopol) June 1, 2021
RCT: Among patient with recent ischemic stroke without known atrial fibrillation, implantable loop recorder monitoring for 12 months detects more occurrences of AF compared with conventional external loop recorder monitoring for 30 days (15.3% vs. 4.7%) – “further research is needed to compare clinical outcomes associated with these monitoring strategies”.
2 Jun, 2021 | 08:30h | UTCEffect of Implantable vs. Prolonged External Electrocardiographic Monitoring on Atrial Fibrillation Detection in Patients With Ischemic Stroke: The PER DIEM Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Detection of Subclinical Atrial Fibrillation After Stroke: Is There Enough Evidence to Treat? – JAMA (free for a limited period)
Commentary: Implantable device more effective at detecting atrial fibrillation than standard of care – News Medical
Covid pandemic over in Britain, say experts.
2 Jun, 2021 | 08:31h | UTCCovid pandemic over in Britain, say experts – The Telegraph
Related: In rich countries, vaccines are making Covid-19 a manageable health issue – The Guardian AND Covid: Zero daily deaths announced in UK for first time – BBC AND Expert reaction to zero COVID-related deaths reported today – Science Media Centre
RCT: Insertable cardiac monitors used for 12 months detect more atrial fibrillation than usual care in patients with a recent ischemic stroke (12.1% vs. 1.8%) – “further research is needed to understand whether identifying AF in these patients is of clinical importance”.
2 Jun, 2021 | 08:29h | UTCEffect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Detection of Subclinical Atrial Fibrillation After Stroke: Is There Enough Evidence to Treat? – JAMA (free for a limited period)
AUA Guideline | Renal Mass and Localized Renal Cancer: Evaluation, Management, and Follow Up.
2 Jun, 2021 | 08:27h | UTCCommentary: AUA updates guideline on renal masses and localized renal cancer – Urology Times
[Press release – not published yet] The city of Serrana in Brazil has seen a 95% drop in Covid-19 deaths after almost all adults were vaccinated with Chinese CoronaVac – The findings suggest the pandemic can be controlled after 75% of people are fully vaccinated.
2 Jun, 2021 | 08:39h | UTCCommentaries: Study in Brazilian town shows 95% efficacy of Sinovac’s vaccine in reducing death by COVID-19 – Global Times AND Brazil Covid: Deaths plunge after town’s adults vaccinated – BBC AND Sinovac vaccine restores a Brazilian city to near normal – Associated Press
JAMA editor-in-chief stepping down after backlash from podcast that questioned racism in medicine.
2 Jun, 2021 | 08:28h | UTCSee also: JAMA editor in chief steps down over tweet that questioned racism in medicine – MarketWatch AND The Editor Of A Top Medical Journal Is Leaving After The Publication Said “No Physician Is Racist” – Buzzfeed News
JAMA Editorial: To Howard Bauchner, MD, Visionary Editor in Chief of JAMA—A Sincere Thank You and a Fond Farewell
China reports first known human case of H10N3 bird flu.
2 Jun, 2021 | 08:23h | UTCChina reports first known human case of H10N3 bird flu – LiveScience
See also: China reports first human case of H10N3 bird flu – CNBC
M-A: After an acute coronary syndrome treated with coronary stenting, dual antiplatelet therapy (DAPT) for 1 to 3 months followed by P2Y12 inhibitor monotherapy is associated with improved outcomes compared with traditional DAPT for 12 months.
2 Jun, 2021 | 08:26h | UTCMeta-Analysis of Duration of Dual Antiplatelet Therapy in Acute Coronary Syndrome Treated With Coronary Stenting – American Journal of Medicine (link to abstract – $ for full-text)
Systematic review: Driving performance under treatment of most frequently prescribed drugs for mental disorders – 31% of schizophrenic or schizoaffective patients under antipsychotics, and 18% of unipolar and bipolar patients under antidepressants showed severe impairment in skills relevant for driving.
2 Jun, 2021 | 08:24h | UTC
The ‘time has come’ for a global pandemic treaty, WHO’s Tedros says.
1 Jun, 2021 | 08:21h | UTCThe ‘Time Has Come’ For A Global Pandemic Treaty, WHO’s Tedros Says – NPR
See also: Will a global preparedness treaty help or hinder pandemic preparedness? – BMJ Global Health
WHO renames COVID-19 variants with the Greek alphabet (i.e., Alpha, Beta, Gamma, etc), making them simple, easy to say and remember. The naming system aims to prevent calling COVID-19 variants by the places where they are detected, which is stigmatizing & discriminatory.
1 Jun, 2021 | 08:26h | UTCTracking SARS-CoV-2 variants – World Health Organization
Commentaries: The name game for coronavirus variants just got a little easier – STAT AND Covid: WHO renames UK and other variants with Greek letters – BBC
Study shows low risk of SARS-CoV-2 reinfection 1 year after primary infection.
1 Jun, 2021 | 08:23h | UTCEditorial: Protection Because of Prior SARS-CoV-2 Infection
Commentary on Twitter
Lombardy, Italy was one of the worst-hit places in the world in the 1st wave of the pandemic. Now, a year later, how many had reinfections?
0.3%
And 13-15 X infections for those who did not have covidhttps://t.co/ewpMRcPIMB @JAMAInternalMed pic.twitter.com/I7z2L04Evp— Eric Topol (@EricTopol) May 28, 2021
Where could the next coronavirus jump to humans? New research offers clues.
1 Jun, 2021 | 08:18h | UTCWhere could the next coronavirus jump to humans? New research offers clues. – Vox
COVID has caused ‘mass trauma,’ worsening mental health globally.
1 Jun, 2021 | 08:14h | UTCCOVID Has Caused ‘Mass Trauma,’ Worsening Mental Health Globally – Health Policy Watch
Perspective | Can I get AstraZeneca now and Pfizer later? Why mixing and matching COVID vaccines could help solve many rollout problems.
1 Jun, 2021 | 08:20h | UTC
Vaccines that can protect against many coronaviruses could prevent another pandemic.
1 Jun, 2021 | 08:15h | UTCVaccines that can protect against many coronaviruses could prevent another pandemic – Science (a few articles per month are free)
M-A: Delivery room interventions for hypothermia in preterm neonates – “use of a plastic bag or wrap with a plastic cap or with heated humidified gas was associated with lower risk of major brain injury and mortality”.
1 Jun, 2021 | 08:10h | UTCDelivery Room Interventions for Hypothermia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)
How a superspreader festival seeded Covid across India.
1 Jun, 2021 | 08:17h | UTCHow a superspreader festival seeded Covid across India – The Guardian
USPSTF Statement: Clinicians should offer behavioral counseling interventions to promote healthy weight gain and prevent excess gestational weight gain in pregnancy.
1 Jun, 2021 | 08:08h | UTCEvidence Report: Counseling and Behavioral Interventions for Healthy Weight and Weight Gain in Pregnancy – JAMA
Author Interview: USPSTF Recommendation: Behavioral Counseling Interventions for Healthy Weight and Weight Gain in Pregnancy – JAMA
JAMA Patient Page: Behavioral Interventions for Healthy Weight Gain During Pregnancy
M-A: Triple vs. dual inhaler therapy in patients with moderate to severe asthma – fewer severe asthma exacerbations, but without significant differences in quality of life or mortality.
1 Jun, 2021 | 08:12h | UTCTriple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Commentary on Twitter
Among patients with moderate to severe asthma, triple therapy compared with dual therapy was significantly associated with fewer severe asthma exacerbations and modest improvements in asthma control but no significant difference in quality of life https://t.co/icKsWu0Md9 #ATS2021
— JAMA (@JAMA_current) May 19, 2021
Podcast | Osteoporosis in Primary Care.
1 Jun, 2021 | 08:06h | UTC#277 Bone Up on Osteoporosis in Primary Care with Dr. Carolyn Crandall – The Curbsiders
AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn’s Disease.
1 Jun, 2021 | 08:07h | UTCTechnical Review: AGA Technical Review on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn’s Disease
Clinical Decision Support Tool / Algorithm: Medical Management of Adult Outpatients With Moderate to Severe Lunminal Crohn’s Disease
Commentary on Twitter
Here are the @AmerGastroAssn guidelines on the management of moderate-severe Crohn disease. #GITwitter #GI #gut #IBD https://t.co/VlT4xTUE8t pic.twitter.com/ayYlpVkkod
— John Damianos, M.D. (@john_damianosMD) May 28, 2021