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RCT: Prophylactic post-exposure prophylaxis with Bamlanivimab reduced the incidence of Covid-19 among residents and staff of skilled nursing and assisted living facilities.

4 Jun, 2021 | 10:40h | UTC

Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities: A Randomized Clinical Trial – JAMA

Editorial: Bamlanivimab for Prevention of COVID-19

 


[Preprint] Covid-19 B.1.617.2 variant of concern (Delta) is associated with increased transmissibility compared to B.1.1.7 (Alpha) that will rapidly lead to B.1.617.2 becoming the prevailing variant in the UK.

4 Jun, 2021 | 10:36h | UTC

Interim estimates of increased transmissibility, growth rate, and reproduction number of the Covid-19 B.1.617.2 variant of concern in the United Kingdom – medRxiv

Related: Covid: Indian variant ‘now dominant’ in the UK – BBC

 


United States Unveils Global Vaccine Sharing Scheme for 80 Million Doses by End June

4 Jun, 2021 | 10:32h | UTC

BREAKING – United States Unveils Global Vaccine Sharing Scheme for 80 Million Doses by End June – Health Policy Watch

See also: Statement by President Joe Biden on Global Vaccine Distribution – The White House

 


Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients.

4 Jun, 2021 | 10:26h | UTC

Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients – Annals of Intensive Care

 


RCT: No benefit from passive leg raising during cardiopulmonary resuscitation in out-of-hospital cardiac arrest.

4 Jun, 2021 | 10:28h | UTC

Clinical outcomes and safety of passive leg raising in out-of-hospital cardiac arrest: a randomized controlled trial – Critical Care

 

Commentary on Twitter

 


WHO: Vaccinating kids ‘not a high priority’ amid shortage

4 Jun, 2021 | 10:31h | UTC

WHO: Vaccinating kids ‘not a high priority’ amid shortage – Associated Press

Related: WHO: Wealthy nations urged to delay youth Covid vaccines, donate to solidarity scheme AND Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”. AND Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”. AND Vaccinating children before poor morally wrong, Oxford scientist says – BBC

 


M-A: In hypoxemic non-hypercapnic patients, early extubation followed by noninvasive ventilation can reduce the total number of days of invasive mechanical ventilation (mean difference, − 2.04 days), without effects in ICU mortality.

4 Jun, 2021 | 10:27h | UTC

Effects of early extubation followed by noninvasive ventilation versus standard extubation on the duration of invasive mechanical ventilation in hypoxemic non-hypercapnic patients: a systematic review and individual patient data meta-analysis of randomized controlled trials – Critical Care

 


ANCA-Associated Vasculitis: An Update.

4 Jun, 2021 | 10:23h | UTC

ANCA-Associated Vasculitis: An Update – Journal of Clinical Medicine

 


RCT: Among patients with ANCA-associated vasculitis without severe glomerulonephritis or alveolar hemorrhage treated with Rituximab, a reduced-dose glucocorticoids regimen (prednisolone 0.5 mg/kg/d) was noninferior to a high-dose glucocorticoid regimen (prednisolone 1 mg/kg/d) for the induction of disease remission.

4 Jun, 2021 | 10:25h | UTC

Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial – JAMA

 


Countries hit hardest by COVID-19 – estimated mortality countries will have on September 1, 2021.

3 Jun, 2021 | 11:09h | UTC

Countries Hit Hardest by COVID-19 – Think Global Health

 

Commentary on Twitter (thread – click for more)

 


Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

3 Jun, 2021 | 11:06h | UTC

6-month multidisciplinary follow-up and outcomes of patients with paediatric inflammatory multisystem syndrome (PIMS-TS) at a UK tertiary paediatric hospital: a retrospective cohort study – The Lancet Child & Adolescent Health

Commentary: Most severe effects of MIS-C in children typically resolve within six months, new research suggests – CNN AND Children who developed a rare inflammation disease after COVID-19 are mostly better after 6 months, but some still suffer fatigue and anxiety, a small UK study found – Insider AND Most severe effects of PIMS-TS resolved at six months – HealthDay

 

Commentary on Twitter

 


Diagnosis and management of diabetes insipidus for the internist: an update

4 Jun, 2021 | 10:22h | UTC

Diagnosis and management of diabetes insipidus for the internist: an update – Journal of Internal Medicine

 


Tracking Coronavirus Vaccinations Around the World.

3 Jun, 2021 | 11:01h | UTC

Tracking Coronavirus Vaccinations Around the World – The New York Times

 


What We Know About the Dangerous COVID B.1.617.2 (Delta) Variant – “the Delta variant may soon become the most dominant COVID strain in the world and lead to rapid outbreaks in countries without high vaccination rates”.

3 Jun, 2021 | 11:05h | UTC

What We Know About the Dangerous COVID B.1.617.2 (Delta) Variant – Intelligencer

 

Commentary on Twitter

 


A pandemic upside: The flu virus became less diverse, simplifying the task of making flu shots.

3 Jun, 2021 | 10:57h | UTC

A pandemic upside: The flu virus became less diverse, simplifying the task of making flu shots – STAT

 


RCT: Among patients with Type 2 diabetes treated with basal insulin with poor glycemic control (mean baseline HbA1c level = 9.1%), continuous glucose monitoring reduced HbA1c level by 0.4% compared to usual care (8.0% and 8.4%). Patient engagement (i.e., adherence, diet, physical activity in response to CGM readings) was the most likely source of improved glycemic control.

3 Jun, 2021 | 10:54h | UTC

Effect of Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes Treated With Basal Insulin: A Randomized Clinical Trial – JAMA

Editorial: Broadening Access to Continuous Glucose Monitoring for Patients With Type 2 Diabetes – JAMA

Commentary: Studies support wider CGM access in type 2 diabetes – medwire News

 

Commentary on Twitter

 


Guideline: Diagnosis and management of acute lower gastrointestinal bleeding.

3 Jun, 2021 | 10:49h | UTC

Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Endoscopy

 


Brazilian town experiment shows mass vaccination can wipe out COVID-19.

3 Jun, 2021 | 10:59h | UTC

Brazilian town experiment shows mass vaccination can wipe out COVID-19 – Science (a few articles per month are free)

Related: [Press release – not published yet] The city of Serrana in Brazil has seen a 95% drop in Covid-19 deaths after almost all adults were vaccinated with Chinese CoronaVac – The findings suggest the pandemic can be controlled after 75% of people are fully vaccinated.

 


AHA Statement: Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood Pressure or Cholesterol: Who, What, and How?

3 Jun, 2021 | 10:52h | UTC

Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood Pressure or Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association – Hypertension

News Release: ‘Prescription’ to sit less, move more advised for mildly high blood pressure and cholesterol – American Heart Association

Commentary: AHA: Physical Activity Should First-line Therapy as BP, LDL Tick Upwards – TCTMD

 


Doctors tell how to make the most of your telehealth visits.

3 Jun, 2021 | 10:39h | UTC

Doctors Tell How to Make the Most of Your Telehealth Visits – Kaiser Health News

 


ACP offers guidance on physician suicide prevention and the role of a healing community from an ethics perspective.

3 Jun, 2021 | 10:45h | UTC

News release: ACP offers guidance on physician suicide prevention and the role of a healing community from an ethics perspective – American College of Physicians

Original study: Physician Suicide Prevention and the Ethics and Role of a Healing Community: an American College of Physicians Policy Paper – Journal of General Internal Medicine

 


RCT: Adjuvant Nivolumab vs. Placebo in Muscle-Invasive Urothelial Carcinoma.

3 Jun, 2021 | 10:36h | UTC

Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma – New England Journal of Medicine

 


M-A: Parenting interventions to promote early child development in the first three years of life.

3 Jun, 2021 | 10:37h | UTC

Parenting interventions to promote early child development in the first three years of life: A global systematic review and meta-analysis – PLOS Medicine

 


WHO: New US$50 billion health, trade and finance roadmap to end the pandemic and secure a global recovery.

2 Jun, 2021 | 08:44h | UTC

New US$50 billion health, trade and finance roadmap to end the pandemic and secure a global recovery – World Health Organization

Commentary: Global Leaders Call for $50-billion Investment to End COVID-19, boost economies – Health Policy Watch

 


Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men.

2 Jun, 2021 | 08:37h | UTC

Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men – Science (a few articles per month are free)

Related: CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.

 

Commentary on Twitter

https://twitter.com/rfsquared/status/1399803644288061442

 


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