Archives
More data suggests no cardiovascular benefit from Omega-3 supplementation – secondary analysis of STRENGHT trial did not show an association between achieved Omega-3 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk.
8 Jun, 2021 | 09:19h | UTCOriginal study: #AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk
RCT: Heart-protecting drugs likely unnecessary for most breast cancer patients undergoing adjuvant treatment.
8 Jun, 2021 | 09:15h | UTCCommentaries: Heart-protecting drugs likely unnecessary for many breast cancer patients – American College of Cardiology
RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk.
7 Jun, 2021 | 00:01h | UTC
Commentary on Twitter
https://twitter.com/RenatoDLopes1/status/1400962037610582026
Six months of COVID vaccines: what 1.7 billion doses have taught scientists.
6 Jun, 2021 | 23:57h | UTCSix months of COVID vaccines: what 1.7 billion doses have taught scientists – Nature
See also: Coronavirus (COVID-19) Vaccinations – Our World in Data
Related commentary on Twitter
• To administer the first half a billion vaccines took 113 days
• The second half a billion 30 days
• The third half a billion 23 days
• And the fourth half a billion were administered in the last 16 daysWe keep on counting on @OurWorldInData here: https://t.co/7lOyDamxxx pic.twitter.com/Pg7OPJxliI
— Max Roser (@MaxCRoser) June 4, 2021
Review: Management of patients with venous thromboembolism after the initial treatment period.
8 Jun, 2021 | 09:13h | UTC
WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic.
6 Jun, 2021 | 23:56h | UTCWHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic – Nature
Related: WHO validates Sinovac-CoronaVac COVID-19 vaccine for emergency use and issues interim policy recommendations. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Study shows reduced neutralizing antibody activity induced by Pfizer–BioNTech vaccine against SARS-CoV-2 variants of concern B.1.617.2 (Delta) and B.1.351 (Beta).
6 Jun, 2021 | 23:59h | UTC
Commentary on Twitter (thread – click for more)
“Immune escape” in #DeltaVariant. That’s the latest finding – that #B16172 is as bad for antibody neutralization as the Beta variant #B1351 from South Africa 🇿🇦. 1st dose alone very small effect— 2 doses needed, but weakest against Delta. Let’s walk through evidence 🧵 #COVID19 https://t.co/GurgkNVgiY pic.twitter.com/o0s9WIudCW
— Eric Feigl-Ding (@DrEricDing) June 5, 2021
Case report: Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT).
6 Jun, 2021 | 23:55h | UTC
More data on the harmful effects of the COVID-19 pandemic on the mental health of adolescents.
6 Jun, 2021 | 23:52h | UTCCommentaries: A lost generation? COVID-19 and adolescent mental health – The Lancet Psychiatry AND COVID-19 pandemic has had significant impact on the mental health of adolescents – Columbia University Mailman School of Public Health
Commentary on Twitter (thread – click for more)
https://twitter.com/TheLancetPsych/status/1400783180937011202
2 new meta-analysis detail neurologic and psychiatric conditions in COVID-19.
6 Jun, 2021 | 23:54h | UTCNeurologic, psychiatric conditions common in COVID-19 – CIDRAP
Challenges and solutions for physician mothers: a critical review of the literature.
6 Jun, 2021 | 23:46h | UTC
Commentary on Twitter
Challenges and Solutions for Physician Mothers: A Critical Review of the Literature in @MayoProceedings
By @sherry_chesak @anjalibhagramd et al.#WomenInMedicine @AMWADoctors https://t.co/RXvXt739PN pic.twitter.com/7aNuA9JVJQ— Mayo Clinic GRIT (@MayoGRIT) April 9, 2021
Perspective | Could statins do more than lower cholesterol in patients with COVID-19? – “Don’t Start, Don’t Stop”.
6 Jun, 2021 | 23:49h | UTCCould Statins Do More Than Lower Cholesterol in Patients With COVID-19? – JAMA
Opinion | “Doctors have been blamed for the rise in black fungus in India, but the COVID treatment guidelines could be contributing” – improper use of antibiotics and higher than usual doses of corticosteroids may be contributing to the emergence of mucormycosis and other fungal co-infections.
6 Jun, 2021 | 23:48h | UTCRelated: The Emergence of COVID-19 Associated Mucormycosis: Analysis of Cases From 18 Countries – The Lancet AND What Is ‘Black Fungus’? And Why Is It Spreading Among India’s COVID Patients? – NPR AND Mucormycosis: The ‘black fungus’ maiming Covid patients in India AND What is mucormycosis, the fungal infection affecting COVID patients in India? – The Conversation
RCT: Early, intensive mobilization poststroke may harm patients.
6 Jun, 2021 | 23:45h | UTCFatal and Nonfatal Events Within 14 days After Early, Intensive Mobilization Poststroke – Neurology
Moving from bytes to bedside: a systematic review on the use of artificial intelligence in the intensive care unit.
6 Jun, 2021 | 23:42h | UTC
Commentary on Twitter
Overview of current maturity of using #ArtificialIntelligence in #ICU, research methodologies, risk of bias: SR including 494 studies. To date, vast majority of published ICU #AI models remain in prototyping/development environment, not tested at bedside. https://t.co/kTpSy2Is7J https://t.co/oU11J3XYjA pic.twitter.com/tKIwQYqgRH
— Intensive Care Medicine (@yourICM) June 5, 2021
M-A: Direct comparison of preoperative imaging modalities for localization of primary hyperparathyroidism – “choline PET-CT would be the best preoperative imaging modality for localization of primary hyperparathyroidism”.
6 Jun, 2021 | 23:40h | UTCJAMA Otolaryngology – Head & Neck Surgery (free for a limited period)
Invited commentary: Localization Studies for Parathyroid Surgery (free for a limited period)
Investigation | Covid 19: How harm reduction advocates and the tobacco industry capitalized on the pandemic to promote nicotine.
6 Jun, 2021 | 23:51h | UTCCommentaries: Researchers report how the tobacco and e-cigarette industry capitalized on COVID-19 to promote smoking – News Medical AND Investigation discredits studies suggesting lower COVID-19 risk for smokers
M-A: The benefit of dysphagia screening in adult patients with stroke.
6 Jun, 2021 | 23:43h | UTC
Update on the diagnosis and treatment of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome.
6 Jun, 2021 | 23:37h | UTCUpdate on the Diagnosis and Treatment of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome: A Review – JAMA Oncology (free for a limited period)
Viewpoint | A national goal to advance health equity through value-based payment.
6 Jun, 2021 | 23:39h | UTCA National Goal to Advance Health Equity Through Value-Based Payment – JAMA
Another study shows a high frequency of antibiotic use among patients hospitalized with Covid-19 (85.2%), despite low rates of confirmed secondary bacterial infections.
4 Jun, 2021 | 10:43h | UTCCommentaries: Very high use of antibiotics in COVID-19 treatment could be reduced – University of Glasgow AND More evidence of frequent antibiotic use noted in COVID patients – CIDRAP AND Covid-19: Antimicrobial use was high during first wave despite bacterial co-infections being rare, study finds – The BMJ
Related: Many hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT
Commentary on Twitter (thread – click for more)
Our paper on co-infections, secondary infections & antimicrobial use in patients hospitalised with #COVID19 in UK during the 1st wave is out in @LancetMicrobe!@ISARIC1 @CCPUKstudy @CVRinfo @UofGlasgow @EdinburghUni @LivUni @imperialcollege https://t.co/QYU1B2Eyup
A🧵
— Antonia Ho (@DrToniHo) June 3, 2021
M-A: Prehospital Tranexamic Acid reduces mortality among bleeding trauma patients without increasing the risk of venous thromboembolism.
6 Jun, 2021 | 23:34h | UTCThe impact of prehospital TXA on mortality among bleeding trauma patients: A systematic review and meta-analysis – Journal of Trauma and Acute Care Surgery (link to abstract – $ for full-text)
Commentary: Prehospital TXA for Trauma – Meta-analysis – JournalFeed
RCT: No benefit from posterior quadratus lumborum block in total hip arthroplasty.
6 Jun, 2021 | 23:35h | UTC
Commentary on Twitter
In the context of a multimodal postoperative analgesic strategy, providing a quadratus lumborum block using ropivacaine resulted in no less morphine consumption or pain in the first 24 postoperative hours compared to saline injection #visualabstract https://t.co/cvxuQ9AQPQ pic.twitter.com/HP5EwrKagx
— Anesthesiology (@_Anesthesiology) April 20, 2021
Cohort study: long working hours (more than 55 h/week) linked to increased risk of recurrent coronary events.
6 Jun, 2021 | 23:32h | UTCLong Working Hours and Risk of Recurrent Coronary Events – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Working long hours may increase odds of second heart attack – American College of Cardiology AND Recurrent CHD Risk Up With Long Working Hours After First MI – HealthDay AND Longer Work Hours After MI Tied to Higher Risk of Recurrent Events – TCTMD
In a Mendelian randomization study, researchers found no genetic evidence to support an association between Vitamin D levels and COVID-19 susceptibility, severity, or hospitalization.
4 Jun, 2021 | 10:35h | UTCCommentary: Vitamin D may not provide protection from COVID-19 susceptibility or disease severity, study suggests – PLOS
Related: Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19. AND RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19