Archives
COVID-19 Imaging: What we know now and what remains unknown.
9 Jun, 2021 | 08:27h | UTCCOVID-19 Imaging: What We Know Now and What Remains Unknown – Radiology
Radiology malpractice cases most often involve cancer-related diagnostic errors.
10 Jun, 2021 | 09:27h | UTCRadiology malpractice cases most often involve cancer-related diagnostic errors – Health Imaging
Original study: Oncologic Errors in Diagnostic Radiology: A 10-Year Analysis Based on Medical Malpractice Claims – Journal of the American College of Radiology (link to abstract – $ for full-text)
Perspective | How COVID changed science.
9 Jun, 2021 | 08:24h | UTCHow COVID Changed Science – Scientific American
Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.
9 Jun, 2021 | 08:22h | UTC
M-A: Hospital-at-home interventions for patients with chronic disease who present to the emergency department – similar mortality risk, lower risk for readmission, lower depression and anxiety scores, and a lower risk for long-term care admission vs. in-hospital stay.
9 Jun, 2021 | 08:20h | UTCInvited commentary: Hospitalization at Home for Patients With Acute Exacerbation of Chronic Disease—Further Evidence to Inform Practice – JAMA Network Open
Related: Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient AND Randomized trial: Admission Avoidance Hospital at Home + Geriatric Assessment led to similar outcomes compared to hospital admission for older persons AND Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – Approximately 1 in 5 were admitted within 14 days. Higher oxygen saturation was associated with decreased odds of transfer, whereas higher comorbidity burden was associated with increased risk.
China to offer COVID-19 vaccine to children as young as three.
9 Jun, 2021 | 08:26h | UTCChina to offer COVID-19 vaccine to children as young as three – MedicalXpress
See also: Sinovac says its vaccine is safe for children as young as 3 – Associated Press
Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.
9 Jun, 2021 | 08:12h | UTCOriginal Guideline: WHO Consolidated Guidelines on Tuberculosis, Module 4: Treatment – Drug-Resistant Tuberculosis Treatment
Commentary on Twitter
🆕💥💥@ERSpublications
WHO guidelines on the treatment of drug-resistant TB contain the latest recommendations on shorter or longer all oral treatment regimens for patients with drug-resistant TB, including the medicines to be used& supportive measures https://t.co/qeeftVYdYN pic.twitter.com/4NKNNjz3Gh— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 8, 2021
No health issues in babies whose moms got flu vaccine while pregnant.
9 Jun, 2021 | 08:17h | UTCNo health issues in babies whose moms got flu vaccine while pregnant – CIDRAP
Original study: Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes – JAMA (free for a limited period)
Editorial: Realizing the Potential of Maternal Influenza Vaccination (free for a limited period)
Commentary on Twitter
https://twitter.com/ericbenchimol/status/1402307635240706048
In youth, COVID-19 causes more complications than flu; fatality is rare.
9 Jun, 2021 | 08:23h | UTCOriginal study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics
Opinion | Scientific publishing’s new weapon for the next crisis: the rapid correction.
9 Jun, 2021 | 08:14h | UTCScientific publishing’s new weapon for the next crisis: the rapid correction – STAT
FDA approvement of Alzheimer’s drug sparks controversy among doctors.
9 Jun, 2021 | 08:18h | UTCNews release: FDA Grants Accelerated Approval for Alzheimer’s Drug – U.S. Food & Drug Administration
Commentaries: ICER Issues Statement on the FDA’s Approval of Aducanumab for Alzheimer’s Disease – Institute for Clinical and Economic Review AND Landmark Alzheimer’s Drug Approval Confounds Research Community – Nature AND FDA approves Alzheimer’s drug from Biogen, against experts’ advice – NBC News AND F.D.A. Approves Alzheimer’s Drug Despite Fierce Debate Over Whether It Works – The New York Times (a few articles per month are free) AND Alzheimer’s drug approved despite doubts about effectiveness – Science (a few articles per month are free) AND The FDA Has Approved A New Alzheimer’s Drug — Here’s Why That’s Controversial – NPR AND Opinion: Bad medicine: aducanumab is a lackluster drug with a high price tag – STAT
Current state of analgesia and sedation in the pediatric intensive care unit.
9 Jun, 2021 | 08:09h | UTC
RCT: Vaginal administration of misoprostol is superior to buccal administration of misoprostol along with a Foley catheter for induction of labor.
9 Jun, 2021 | 08:11h | UTCBuccal vs vaginal misoprostol combined with Foley catheter for cervical ripening at term (the BEGIN trial): a randomized controlled trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/AJOG_thegray/status/1393529144395374592
Short review: Neurological complications of COVID-19.
8 Jun, 2021 | 09:36h | UTCNeurological complications of COVID-19 – Intensive Care Medicine
Commentary on Twitter
NeuroCOVID potential mechanism(s)?
🧠 #COVID19 neuro-complications
🧠 direct neuroinvasion
🧠 inflammatory/autoimmune
🧠 vascular
+
🧠 #ICU complications
🧠 drugs toxicity/side effects
🧠 PICS/PACS & PTSD
Challenging to identify/diagnose: strictly monitor! https://t.co/0YlAoanUFo pic.twitter.com/unM0SWFR7L— Intensive Care Medicine (@yourICM) June 7, 2021
Difficult airway management in neonates and infants: knowledge of devices and a device-oriented strategy.
9 Jun, 2021 | 08:08h | UTC
Underlying medical conditions associated with severe COVID-19 illness among children – the strongest risk factors for hospitalization were chronic and complex chronic diseases, type 1 diabetes, and obesity.
8 Jun, 2021 | 09:37h | UTCCommentaries: Underlying illness, respiratory infection raise risk for severe COVID in kids – CIDRAP AND COVID-19 in Children—Not Just Little Adults – JAMA Network Open
Commentary on Twitter
This cross-sectional study found a higher risk of severe #COVID19 illness among children with medical complexity and certain underlying conditions, such as type 1 diabetes, cardiac and circulatory congenital anomalies, and obesity. https://t.co/ifq1Ao0HKS
— JAMA Network Open (@JAMANetworkOpen) June 7, 2021
Are SARS-CoV-2 Human Challenge Trials Ethical? – “A clinical trial is underway in the UK in which young, healthy participants are exposed deliberately to SARS-CoV-2 to assess the viral inoculum needed to produce an infection and to test vaccine efficacy”.
8 Jun, 2021 | 09:29h | UTCAre SARS-CoV-2 Human Challenge Trials Ethical? – JAMA Internal Medicine
Related: World’s first coronavirus “Human Challenge” study receives ethics approval in the UK (several texts on the subject)
Commentary on Twitter
I am not convinced of #SARSCoV2 #ChallengeTrials. You should not pay volunteers. If things go wrong, there is no effective treatment. What will be learnt from mild disease, when you are interested in severe disease? #COVID19 #Covid #Corona #coronavirushttps://t.co/JjXDJDfOl2
— Martin Michaelis (@MartMichaelis) June 8, 2021
The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – careful use of antibiotics and corticosteroids and closely monitoring blood glucose levels are some of the strategies suggested by the authors.
8 Jun, 2021 | 09:34h | UTC
Multicenter Epidemiologic Study of Coronavirus Disease–Associated Mucormycosis, India – Uncontrolled diabetes mellitus was the most common underlying disease; improper glucocorticoid use was independently associated with the disease.
8 Jun, 2021 | 09:33h | UTCCommentary: COVID19: Secondary Infections Still a Big Challenge in India – News Click
Commentary on Twitter
New study from India on mucormycosis
– COVID-19 has led to increases in mucormycosis, partly from inappropriate steroid use
– Uncontrolled diabetes was the most common underlying disease
Better diabetes care & rational steroid use are key!https://t.co/Wv8kCyTDtK pic.twitter.com/KK78BKg2Xf
— Madhu Pai, MD, PhD (@paimadhu) June 7, 2021
Report: 376,000 people in UK have had long Covid symptoms for at least a year.
8 Jun, 2021 | 09:27h | UTC376,000 people in UK have had long Covid symptoms for at least a year – ONS – The Guardian
Original report: Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 4 June 2021 – Office for National Statistics
Practice Pointer | Mask related acne (“maskne”) and other facial dermatoses.
8 Jun, 2021 | 09:24h | UTCMask related acne (“maskne”) and other facial dermatoses – The BMJ
Commentary on Twitter
The term “maskne” has become increasingly popular during the pandemic, particularly in the media.
This #BMJInfographic presents common distributions that can be used as a starting point for assessment @will_s_t https://t.co/mKQUaN3PYY pic.twitter.com/OCBuFxiY9s
— The BMJ (@bmj_latest) June 7, 2021
Synopsis | Updates to the Pediatrics Asthma Management Guidelines.
8 Jun, 2021 | 09:22h | UTCUpdates to the Pediatrics Asthma Management Guidelines – JAMA Pediatrics (free for a limited period)
Original Guideline: 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group
RCT: Low tidal volume ventilation is not superior to no ventilation during cardiopulmonary bypass in heart surgery.
8 Jun, 2021 | 09:16h | UTCLow Tidal Volume Mechanical Ventilation Against No Ventilation During Cardiopulmonary Bypass in Heart Surgery (MECANO): A Randomized Controlled Trial – CHEST (link to abstract – $ for full-text)
Diagnostic value of cutaneous manifestation of SARS-CoV-2 infection – there was a significant association between skin rashes and a positive swab test result (odds ratio 1.67).
8 Jun, 2021 | 09:26h | UTCDiagnostic value of cutaneous manifestation of SARS-CoV-2 infection – British Journal of Dermatology
Time-to-positivity in bloodstream infection is not a prognostic marker for mortality: analysis of a prospective multicenter randomized control trial.
8 Jun, 2021 | 09:21h | UTC
Commentary on Twitter
🆕💥Analysis Data from RAPIDO RCT
Time to positivity is not associated with mortality, except in Candida spp (longer times associated with worse outcomes), and possibly in Streptococci (shorter times associated with worse outcomes) #IDTwitter #medtwitter https://t.co/v17uT8j7u9— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 7, 2021