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World’s first coronavirus “Human Challenge” study receives ethics approval in the UK

18 Feb, 2021 | 03:14h | UTC

World’s first coronavirus Human Challenge study receives ethics approval in the UK – GOV.UK

Commentaries: Covid-19: World’s first human trials given green light in UK – BBC AND UK to infect up to 90 healthy volunteers with Covid in world first trial – The Guardian

WHO Guidance on the subject: Feasibility, potential value and limitations of establishing a closely monitored challenge model of experimental COVID-19 infection and illness in healthy young adult volunteers – World Health Organization AND Key criteria for the ethical acceptability of COVID-19 human challenge studies – World Health Organization

See also: Challenge Trials—Could Deliberate Coronavirus Exposure Hasten Vaccine Development? – JAMA AND Ethical guidelines for deliberately infecting volunteers with COVID-19 – Journal of Medical Ethics AND Challenge trials can speed development of a Covid-19 vaccine. Planning for them needs to start now – STAT AND Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models – New England Journal of Medicine AND Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure – The Journal of Infectious Diseases AND Ethics of controlled human infection to address COVID-19 – Science AND Extraordinary diseases require extraordinary solutions – Vaccine


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