Archives
Special Issue: Peri‐operative and critical care management of the brain ‐ current evidence.
11 Jan, 2022 | 02:36h | UTCEditorials:
In search of the perfect outcome in neuroanaesthesia and neurocritical care
Anaesthesia and the older brain: what should we do?
Review Articles:
Implications of nocebo in anaesthesia care
Acute peri-operative neurocognitive disorders: a narrative review
Pragmatic sedation strategies to prevent secondary brain injury in low-resource settings
Delirium and COVID-19: a narrative review of emerging evidence
Anaesthesia for mechanical thrombectomy: a narrative review
Clinical applications of point-of-care ultrasound in brain injury: a narrative review
Management of status epilepticus: a narrative review
Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review
Management of traumatic brain injury: a narrative review of current evidence
Peri-operative management of patients with Parkinson’s disease
Medical Decisions: Some are Easy and Some Not So Much.
11 Jan, 2022 | 02:31h | UTCMedical Decisions: Some are Easy and Some Not So Much – Stop and Think blog, by John Mandrola
Commentary on Twitter
https://twitter.com/drjohnm/status/1480289256518176770
Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019.
11 Jan, 2022 | 02:30h | UTC
RCT: In premenopausal women with breast cancer, gonadotropin-releasing hormone analogs may preserve ovarian function against chemotherapy-induced gonadotoxic effects.
11 Jan, 2022 | 02:26h | UTCEffects of Gonadotropin-Releasing Hormone Analogs on Ovarian Function Against Chemotherapy-Induced Gonadotoxic Effects in Premenopausal Women With Breast Cancer in China: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Randomized clinical trial finds administration of gonadotropin-releasing hormone analogs (GnRHa) with chemotherapy in premenopausal pts with #BreastCancer reduces risk of premature ovarian insufficiency (#POI) and promotes recovery of ovarian function. https://t.co/gymbKT9GWZ pic.twitter.com/OUOlIwPSsq
— JAMA Oncology (@JAMAOnc) December 30, 2021
RCT: In patients presenting with metastatic breast cancer, early locoregional therapy for the primary site did not improve survival or quality of life.
11 Jan, 2022 | 02:29h | UTCEarly Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108) – Journal of Clinical Oncology (link to abstract – $ for full-text)
Systematic Review: First-generation cephalosporins for the treatment of complicated upper urinary tract infection in adults.
11 Jan, 2022 | 02:23h | UTC
Commentary on Twitter
Interesting! Why not?
🆕💥Systematic literature review First-generation cephalosporins mainly Cefazolin and one study Cefadroxil for the treatment of complicated upper urinary tract infection in adults
Comparators mainly 3d G
Old studies
No meta-analysis https://t.co/EHamKpfKZQ— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) January 10, 2022
Systematic Review: The effectiveness and safety of treatments for recurrent vulvovaginal candidiasis.
11 Jan, 2022 | 02:24h | UTCTreatment for recurrent vulvovaginal candidiasis (thrush) – Cochrane Library
Review: New aspects in the management of hypertension in patients with chronic kidney disease not on renal replacement therapy.
11 Jan, 2022 | 02:22h | UTC
The ‘Ten Commandments’ of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.
11 Jan, 2022 | 02:20h | UTCRelated:
NICE Guideline | Acute heart failure: diagnosis and management.
The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention.
M-A: Fecal immunochemical test to triage patients with possible colorectal cancer symptoms.
11 Jan, 2022 | 02:18h | UTC
Commentary on Twitter
🆕#CuttingEdgeBlog Plain English summary📰
"Worried about symptoms of bowel cancer? A simple stool test may help."@ian_bissett @SawKS88 @ChenLiu_NZ @williamxu_98 @chrisvarghese98
Blog🔗: https://t.co/Pb7zfsfWT3
Based on the paper 🔗: https://t.co/20proTApNd pic.twitter.com/IAUsHIqUrn
— BJS (@BJSurgery) January 10, 2022
Registry Study: Determinants of outcomes following surgery for type A acute aortic dissection.
11 Jan, 2022 | 02:12h | UTC
Commentary on Twitter
Determinants of outcomes following surgery for type A acute aortic dissection: the UK National Adult Cardiac Surgical Audit https://t.co/nKH9jJLjdp #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/5C5jGd4DV6
— European Society of Cardiology Journals (@ESC_Journals) September 30, 2021
Review | Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop.
11 Jan, 2022 | 02:16h | UTC
Commentary from the author on Twitter (thread – click for more)
We were asked to write about balance of harms and benefits of antidepressants based on current knowledge for @DTB_BMJ, a BMJ journal that is famously independent and does not take pharma sponsorship/advertising https://t.co/QCg7Bo1F40 1/n
— Mark Horowitz @markhoro.bsky.social (@markhoro) December 21, 2021
RCT: Early exercise (1 week after surgery) may be safe after breast augmentation.
11 Jan, 2022 | 02:14h | UTCCommentary: Exercise Soon After Breast Plastic Surgery Is Safe, Healthy – HealthDay
RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.
11 Jan, 2022 | 02:10h | UTCHydroxyurea for primary stroke prevention in children with sickle cell anaemia in Nigeria (SPRING): a double-blind, multicentre, randomised, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)
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9 Jan, 2022 | 01:15h | UTCAll Channels (142 specialties and subspecialties)
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Cohort Study: Ciprofloxacin exposure during pregnancy was not associated with miscarriage or major malformations in a nationwide study from Denmark.
11 Jan, 2022 | 02:08h | UTCCiprofloxacin exposure and adverse pregnancy outcomes: a Danish nationwide cohort study – BJOG (link to abstract – $ for full-text)
Cohort study: Among health care workers previously vaccinated with 2 doses of the Pfizer-BioNTech vaccine, receiving a third dose was associated with reduced risk of SARS-CoV-2 infection.
11 Jan, 2022 | 01:35h | UTCEditorial: Booster Vaccination to Reduce SARS-CoV-2 Transmission and Infection – JAMA
Covid-19’s Devastating Effect on Tuberculosis Care — A Path to Recovery.
11 Jan, 2022 | 01:33h | UTC
Commentary on Twitter
In @NEJM today, @TerezaKasaeva @doctorsoumya and I write about
Covid-19’s devastating impact on tuberculosis care & offer suggestions for recoveryhttps://t.co/buOEOPVWwM pic.twitter.com/BfOK3X3MuU
— Madhu Pai, MD, PhD (@paimadhu) January 5, 2022
Review: Rapid diagnostic testing for SARS-CoV-2.
11 Jan, 2022 | 01:34h | UTCRapid Diagnostic Testing for SARS-CoV-2 – New England Journal of Medicine
[Preprint] Lab study shows Omicron infection enhances neutralizing immunity against the Delta variant.
11 Jan, 2022 | 01:29h | UTCOmicron infection enhances neutralizing immunity against the Delta variant – medRxiv
Study shows Covid-19 vaccination is associated with a smaller reduction in transmission of the delta variant compared with the alpha variant.
11 Jan, 2022 | 01:31h | UTC
Commentary on Twitter
Vaccination was associated with a smaller reduction in transmission of the SARS-CoV-2 delta variant than of the alpha variant, and the effects of vaccination decreased over time. #COVID19 #IDTwitter https://t.co/giGzWSx31k pic.twitter.com/HlwBqNGFO1
— NEJM (@NEJM) January 5, 2022
Clinical Practice Guideline Summary: Recommended Drugs and Biologics in Adult Patients with COVID-19.
11 Jan, 2022 | 01:26h | UTC
Commentary on Twitter
Fantastic outpatient treatment approach from Ontario #COVID19 Clinical Practice Guidelines
Risk level:high mod low
Eg:high:Sotrovimab is recommended if NA Remdesivir if NA Fluvoxamine or Budesonide
Paxlovid/Molnupiravir not added coz not yet approved CA https://t.co/dDhj6vA0uv pic.twitter.com/4ucrKIcMn8— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) January 8, 2022
M-A: Fatigue and cognitive impairment in Post-COVID-19 Syndrome.
11 Jan, 2022 | 01:28h | UTC
Covid-19: An urgent call for global “vaccines-plus” action.
11 Jan, 2022 | 01:22h | UTCCovid-19: An urgent call for global “vaccines-plus” action – The BMJ
CDC Report: COVID-19 vaccine safety in children aged 5–11 Years.
9 Jan, 2022 | 01:09h | UTCCommentary: COVID-19 vaccine appears safe in children aged 5–11 Years – News Medical
Commentary on Twitter
Early vaccine safety data for children ages 5–11 years old found that reactions such as fatigue and headaches were commonly reported following Pfizer-BioNTech #COVID19 vaccine. Everyone ages 5 years & older should get vaccinated as soon as possible. https://t.co/D66QgLRWni pic.twitter.com/8I48L5GmcG
— MMWR (@CDCMMWR) December 30, 2021