Archives
German Guideline: Oxygen therapy in the acute care of adult patients.
12 Jan, 2022 | 08:57h | UTCGerman S3 Guideline: Oxygen Therapy in the Acute Care of Adult Patients – Respiration
Two years of coronavirus: how pandemic unfolded around the world.
12 Jan, 2022 | 09:02h | UTCTwo years of coronavirus: how pandemic unfolded around the world – The Guardian
Discriminative accuracy of chronic obstructive pulmonary disease screening instruments in 3 low- and middle-income country settings.
12 Jan, 2022 | 08:54h | UTCDiscriminative Accuracy of Chronic Obstructive Pulmonary Disease Screening Instruments in 3 Low- and Middle-Income Country Settings – JAMA (free for a limited period)
Editorial: Screening for Chronic Obstructive Pulmonary Disease: Unmet Needs and Future Considerations
News release: Simple screening for common lung disease could relieve millions globally – University College London
Commentary from the author on Twitter (thread – click for more)
🔺Screening for #COPD in LMIC🔺
The results of our @COPDGECo study from @ucl are published today in @JAMA_current.
Discriminative Accuracy of COPD Screening Instruments in Low- and Middle-Income Countries
🇳🇵🇵🇪 🇺🇬 https://t.co/7aq8XXfI8E – part of @JAMANetwork— John Hurst (@ProfHurst) January 11, 2022
Clinical Review: Diagnostic reasoning in cardiovascular medicine.
12 Jan, 2022 | 08:49h | UTCDiagnostic reasoning in cardiovascular medicine – The BMJ
RCT: Endoscopic sinus surgery with medical therapy vs. medical therapy alone for chronic rhinosinusitis with nasal polyps.
12 Jan, 2022 | 08:51h | UTCEndoscopic sinus surgery with medical therapy versus medical therapy for chronic rhinosinusitis with nasal polyps: a multicentre, randomised, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW Research—Endoscopic sinus surgery + medical therapy > medical therapy alone in pts w/ chronic rhinosinusitis w/ nasal polyps (although minimal clinically important difference was not met)
From Wytske Fokkens & colleagues https://t.co/VKxCQZ97Am pic.twitter.com/IzXq712lNL
— The Lancet Respiratory Medicine (@LancetRespirMed) January 8, 2022
RCT: Among patients younger than 21 years of age with provoked thromboembolism, anticoagulation for 6 weeks was non-inferior vs. 12 weeks on the risk of recurrence and bleeding events.
12 Jan, 2022 | 08:53h | UTCEffect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DOTT Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Duration of Anticoagulant Treatment for Acute Provoked Venous Thromboembolism in Pediatric Patients – JAMA (free for a limited period)
RCT: In patients with untreated advanced melanoma, treatment with Relatlimab plus Nivolumab was associated with increased median progression-free survival compared with Nivolumab alone (10.1 months vs. 4.6 months).
12 Jan, 2022 | 08:43h | UTCRelatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
The inhibition of two immune checkpoints, LAG-3 and PD-1, provided a greater benefit with regard to PFS than inhibition of PD-1 alone in patients with previously untreated metastatic or unresectable melanoma. https://t.co/idtOgksg74 pic.twitter.com/vx1W9O4Dh6
— NEJM (@NEJM) January 5, 2022
Clinical Update: Management and outcomes of extreme preterm birth.
12 Jan, 2022 | 08:48h | UTCManagement and outcomes of extreme preterm birth – The BMJ
RCT: Eltrombopag added to immunosuppression is associated with improved hematologic response vs. immunosuppression alone in previously untreated patients with severe aplastic anemia.
12 Jan, 2022 | 08:46h | UTCEltrombopag Added to Immunosuppression in Severe Aplastic Anemia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
A randomized trial comparing immunosuppression (horse ATG and cyclosporine) with the same therapy plus eltrombopag showed more rapid and complete responses with the addition of eltrombopag. https://t.co/nH7rkeCMAS pic.twitter.com/i8iTIq8FSG
— NEJM (@NEJM) January 5, 2022
A cluster randomized trial in a yaws-endemic area of Papua New Guinea showed a reduction in the community prevalence of yaws with three rounds of mass administration of azithromycin at 6-month intervals compared with one round of mass administration of azithromycin followed by two rounds of targeted treatment.
12 Jan, 2022 | 08:44h | UTCTrial of Three Rounds of Mass Azithromycin Administration for Yaws Eradication – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Data from a community-based trial in Papua New Guinea suggest that more than one round of mass drug administration should be considered as part of the strategy for yaws eradication. https://t.co/7Cfuz16CUa pic.twitter.com/pVRyefOlTb
— NEJM (@NEJM) January 6, 2022
Phase 2 RCT: Adjunctive ketamine with relapse prevention–based psychological therapy shows promise for the treatment of alcohol use disorder.
12 Jan, 2022 | 08:42h | UTCAdjunctive Ketamine With Relapse Prevention–Based Psychological Therapy in the Treatment of Alcohol Use Disorder – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: People With AUD May Benefit From Combination of Ketamine, Mindfulness Therapy – Psychiatric News Alert
RCT: Among patients with short bulbar urethral strictures, those submitted to transecting excision and primary anastomosis (tEPA) reported more penile complications compared to patients submitted to buccal mucosa grafting (BMG).
12 Jan, 2022 | 08:39h | UTC
Commentary on Twitter
To Transect or Not Transect: Results from the Scandinavian Urethroplasty Study, A Multicentre Randomised Study of Bulbar Urethroplasty Comparing Excision and Primary Anastomosis Versus Buccal Mucosal Graftinghttps://t.co/pO7MS7F65H@veiby_holm @7some pic.twitter.com/Vy4wmc74ul
— European Urology (@EUplatinum) January 10, 2022
Cohort Study: Higher consumption of olive oil linked to lower risk of cardiovascular, cancer, and all-cause mortality.
12 Jan, 2022 | 08:41h | UTCConsumption of Olive Oil and Risk of Total and Cause-Specific Mortality Among U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Higher olive oil intake associated with lower risk of CVD mortality – American College of Cardiology
Systematic Review: Antecolic vs. retrocolic reconstruction after partial pancreaticoduodenectomy.
12 Jan, 2022 | 08:38h | UTCAntecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy – Cochrane Library
Consequences of a diagnostic label: A systematic scoping review and thematic framework.
12 Jan, 2022 | 08:37h | UTC
RCT: Interferon-alpha vs. Hydroxyurea in Polycythemia Vera and Essential Thrombocythemia.
12 Jan, 2022 | 08:35h | UTC
Review: Management of coagulopathy in bleeding patients.
12 Jan, 2022 | 08:34h | UTCManagement of Coagulopathy in Bleeding Patients – Journal of Clinical Medicine
Clinical Guideline: Acute-on-chronic liver failure.
11 Jan, 2022 | 02:43h | UTCAcute-on-Chronic Liver Failure Clinical Guidelines – American Journal of Gastroenterology
Related: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU
Commentary on Twitter
📣NEW ACG Guidelines Acute-on-Chronic #Liver Failure by @JasmohanBajaj et al.
📕https://t.co/T3CqvOAMrj#Cirrhosis #GItwitter #LiverTwitter #MostReadinRed pic.twitter.com/LHwIkUtGZt
— AJG – The American Journal of Gastroenterology (@AmJGastro) January 10, 2022
Perspective: What Sci-Hub’s latest court battle means for research.
12 Jan, 2022 | 08:32h | UTCWhat Sci-Hub’s latest court battle means for research – Nature
European Guidelines on non–muscle-invasive bladder cancer (Ta, T1, and Carcinoma in Situ).
12 Jan, 2022 | 08:32h | UTC
AHA Scientific Statement: Comprehensive management of cardiovascular risk factors for adults with Type 2 Diabetes.
11 Jan, 2022 | 02:40h | UTC
Best Practice Recommendations: Management of adults and children receiving CAR T-cell therapy.
12 Jan, 2022 | 08:31h | UTC
Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.
11 Jan, 2022 | 02:38h | UTCNews Release: Global dementia cases set to triple by 2050 unless countries address risk factors – The Lancet
Commentaries:
Forecasting the prevalence of dementia – The Lancet Public Health
Dementia cases expected to almost triple across the world by 2050 – BBC
Number of adults with dementia to exceed 150m by 2050, study finds – The Guardian
Commentary on Twitter (thread – click for more)
🆕✨First #GBDstudy forecasts global #dementia cases set to triple by 2050 (up from 57m in 2019 to expected 153m people) unless countries address risk factors: #smoking, #obesity, #HighBloodSugar, & low #education🧵👇
Published in @TheLancet @TheLancetPHhttps://t.co/GccTPRroEV
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) January 7, 2022
In 1st, US surgeons transplant pig heart into human patient.
11 Jan, 2022 | 02:34h | UTCIn 1st, US surgeons transplant pig heart into human patient – Associated Press
Position Statement: Prehospital surgical airway management.
11 Jan, 2022 | 02:39h | UTC