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[Preprint] High prevalence of olfactory disorders 18 months after contracting COVID-19.

26 Jan, 2022 | 02:11h | UTC

High prevalence of olfactory disorders 18 months after contracting COVID-19 – medRxiv

Commentaries:

Half of first-wave Covid cases may have lasting harm to sense of smell – The Guardian

Prevalence of olfactory dysfunction 18 months after SARS-CoV-2 infection – News Medical

 


RCT: Acetazolamide prevents adverse altitude effects in COPD and healthy adults.

26 Jan, 2022 | 01:53h | UTC

Acetazolamide to Prevent Adverse Altitude Effects in COPD and Healthy Adults – NEJM Evidence

Related: A Randomized Controlled Trial of the Lowest Effective Dose of Acetazolamide for Acute Mountain Sickness Prevention

 


Mass casualty medicine and anesthesia special issue: science and clinical practice.

26 Jan, 2022 | 02:04h | UTC

Editorials:

Mass casualty medicine: time for a 21st century refresh

Exercising for mass casualty preparedness

Massive transfusion and severe blood shortages: establishing and implementing predictors of futility

Transfusion support during mass casualty events

Embracing uncertainty in mass casualty incidents

Pre-hospital critical care at major incidents

Provision of pre-hospital medical care for terrorist attacks

Higher pre-hospital anaesthesia case volumes result in lower mortality rates: implications for mass casualty care

Improving mass casualty planning in low resource settings: Médecins Sans Frontières and International Committee of the Red Cross perspective

Global lessons learned from COVID-19 mass casualty incidents

Reimagining health preparedness in the aftermath of COVID-19

Preparing for mass casualty events despite COVID-19

Paediatric Anaesthesia:

Paediatric patients in mass casualty incidents: a comprehensive review and call to action

Adaptations to practice and resilience in a paediatric major trauma centre during a mass casualty incident

Pre-hospital Care:

Injury scoring systems for blast injuries: a narrative review

Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort

Establishing quality indicators for pre-hospital advanced airway management: a modified nominal group technique consensus process

Pre-hospital continuous positive airway pressure after blast lung injury and hypovolaemic shock: a modelling study

Preparedness:

Review of the requirements for effective mass casualty preparedness for trauma systems. A disaster waiting to happen?

Learning from terrorist mass casualty incidents: a global survey

Refining mass casualty plans with simulation-based iterative learning

Specific Incidents:

Mass casualty, intentional vehicular trauma and anaesthesia

Chemical, biological, radiological, and nuclear mass casualty medicine: a review of lessons from the Salisbury and Amesbury Novichok nerve agent incidents

Correspondence:

Pre-hospital oral transmucosal fentanyl citrate for trauma analgesia: preliminary experience and implications for civilian mass casualty response

Implications for trauma system development in a low- and middle-income country: the Sri Lanka 2019 Easter Sunday terrorist attack

Development and evaluation of a mass casualty medicine simulation method using figurines

Influx! A game-based learning tool for in-hospital interprofessional disaster preparedness and response

 


RCT: Electronic directly observed therapy is noninferior to in-person observed therapy for ensuring adherence to tuberculosis treatment.

26 Jan, 2022 | 01:58h | UTC

In-Person vs Electronic Directly Observed Therapy for Tuberculosis Treatment Adherence: A Randomized Noninferiority Trial – JAMA Network Open

 

Commentary on Twitter

 


Perspective: The value of patient-reported outcomes in early-phase clinical trials.

26 Jan, 2022 | 01:47h | UTC

The value of patient-reported outcomes in early-phase clinical trials – Nature Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


A review of high impact journals found that misinterpretation of non-statistically significant results from randomized trials was common.

26 Jan, 2022 | 01:50h | UTC

A review of high impact journals found that misinterpretation of non-statistically significant results from randomised trials was common – Journal of Clinical Epidemiology

 


Opinion | “The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice”.

26 Jan, 2022 | 01:52h | UTC

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice – European Journal of Human Genetics

Commentary: ‘Unproven and unethical’: experts warn against genetic embryo tests – The Guardian

 


A registry study with 1,581 cases of Stenotrophomonas maltophilia blood and/or lower respiratory infections suggest Levofloxacin is a reasonable alternative to standard therapy with Trimethoprim-sulfamethoxazole.

26 Jan, 2022 | 01:40h | UTC

Trimethoprim-Sulfamethoxazole versus Levofloxacin for Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 U.S. Hospitals – Open Forum Infectious Diseases

 

Commentary on Twitter

 


An artificial intelligence system can help predict myocardial infarction through retinal scans and minimal personal information.

26 Jan, 2022 | 01:44h | UTC

News release: Using the eye as a window into heart disease – University of Leeds

Original study: Predicting myocardial infarction through retinal scans and minimal personal information – Nature Machine Intelligence (link to abstract – $ for full-text)

 


Fever of unknown origin and incidence of cancer: a population-based cohort study using nationwide Danish registries showed that cancer risk in one year was 1.2%.

26 Jan, 2022 | 01:36h | UTC

Fever of unknown origin and incidence of cancer – Clinical Infectious Diseases (link to abstract – $ for full-text)

 


Systematic Review: Ultrafiltration for acute heart failure.

26 Jan, 2022 | 01:33h | UTC

Ultrafiltration for acute heart failure – Cochrane Library

Commentary: Fluid removal therapy in acute heart failure – Cochrane Library

 


Systematic Review: Delayed introduction of progressive enteral feeds to prevent necrotizing enterocolitis in very low birth weight infants.

26 Jan, 2022 | 01:27h | UTC

Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants – Cochrane Library

Summary: Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants – Cochrane Library

 


Systematic Review: Oral antihistamine‐decongestant‐analgesic combinations for the common cold.

26 Jan, 2022 | 01:31h | UTC

Oral antihistamine‐decongestant‐analgesic combinations for the common cold – Cochrane Library

Commentary: Oral antihistamine-decongestant-analgesic combinations for the common cold – Cochrane Library

 


Review: Point-of-care ultrasound for the trauma anesthesiologist.

26 Jan, 2022 | 01:22h | UTC

Point-of-Care Ultrasound for the Trauma Anesthesiologist – Current Anesthesiology Reports (if the link is paywalled, try this one)

 


Systematic Review: Short intravenous antibiotic courses for urinary infections in young infants.

26 Jan, 2022 | 01:24h | UTC

Short Intravenous Antibiotic Courses for Urinary Infections in Young Infants: A Systematic Review – Pediatrics (link to abstract – $ for full-text)

 


Supplement: Irritable bowel syndrome and related conditions.

26 Jan, 2022 | 01:21h | UTC

Homepage: IBS and Related Conditions – Alimentary Pharmacology and Therapeutics

Review article: epidemiology of IBS and other bowel disorders of gut–brain interaction (DGBI)

Review article: Physical and psychological comorbidities associated with irritable bowel syndrome

Review article: irritable bowel syndrome: natural history, bowel habit stability and overlap with other gastrointestinal disorders

Review article: Diagnosis and investigation of irritable bowel syndrome

Review article: the patients’ experience with irritable bowel syndrome and their search for education and support

Review article: current and future treatment approaches for IBS with constipation

Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS-D) and IBS mixed pattern (IBS-M)

Review article: current and future treatment approaches for pain in IBS

 


Review: Genotypic and phenotypic characteristics of hereditary colorectal cancer.

26 Jan, 2022 | 01:16h | UTC

Genotypic and Phenotypic Characteristics of Hereditary Colorectal Cancer – Annals of Coloproctology

 


ASCO-SNO Guideline: Therapy for diffuse astrocytic and oligodendroglial tumors in adults.

26 Jan, 2022 | 01:19h | UTC

Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline – Journal of Clinical Oncology

 


RCT: CPAP improved outcomes in patients with acute hypoxemic respiratory failure due to COVID-19, but high-flow nasal oxygen was not better than conventional oxygen therapy.

25 Jan, 2022 | 09:50h | UTC

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial – JAMA

Editorial: Defining Optimal Respiratory Support for Patients With COVID-19 – JAMA

 

Commentary on Twitter

 


Review: Treatment for peritoneal metastasis of patients with colorectal cancer.

26 Jan, 2022 | 01:17h | UTC

Treatment for Peritoneal Metastasis of Patients With Colorectal Cancer – Annals of Coloproctology

 


ACP living, rapid review: risk for reinfection after SARS-CoV-2.

25 Jan, 2022 | 09:47h | UTC

Risk for Reinfection After SARS-CoV-2: A Living, Rapid Review for American College of Physicians Practice Points on the Role of the Antibody Response in Conferring Immunity Following SARS-CoV-2 Infection – Annals of Internal Medicine

 

Commentary on Twitter

 


New CPR guidance addresses more contagious COVID-19 variants amidst evolving pandemic.

25 Jan, 2022 | 09:48h | UTC

News release: New CPR guidance addresses more contagious COVID-19 variants amidst evolving pandemic – American Heart Association

See Guidance: 2022 Interim Guidance to Healthcare Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates with Suspected or Confirmed COVID-19: From the Emergency Cardiovascular Care Committee and Get With the Guidelines®-Resuscitation Adult and Pediatric Task Forces of the American Heart Association in Collaboration with the American Academy of Pediatrics, American Association for Respiratory Care, The Society of Critical Care Anesthesiologists, and American Society of Anesthesiologists

 


WHO drops opposition to boosters – recommends third Pfizer jab for adults & two vaccines for children ages 5 & up.

25 Jan, 2022 | 09:45h | UTC

WHO Drops Opposition to Boosters – Recommends Third Pfizer Jab for Adults & Two Vaccines for Children Ages 5 & Up – Health Policy Watch

Related:

WHO updated roadmap for prioritizing uses of COVID-19 vaccines.

WHO advisers weigh in on COVID-19 boosters, Pfizer vaccine in younger kids.

 


A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

25 Jan, 2022 | 09:43h | UTC

Carditis After COVID-19 Vaccination With a Messenger RNA Vaccine and an Inactivated Virus Vaccine: A Case–Control Study – Annals of Internal Medicine

News release: BNT162b2 COVID-19 vaccine associated with increased risk of carditis – American College of Physicians

Related:

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


Early assessment of the clinical severity of the SARS-CoV-2 omicron variant in South Africa.

25 Jan, 2022 | 09:41h | UTC

Early assessment of the clinical severity of the SARS-CoV-2 omicron variant in South Africa: a data linkage study – The Lancet

Commentary: Omicron severity: milder but not mild – The Lancet

 

Commentary on Twitter

 


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