Archives
COVID-19: endemic doesn’t mean harmless.
25 Jan, 2022 | 09:36h | UTCCOVID-19: endemic doesn’t mean harmless – Nature
[Preprint] Cohort study: Reduced risk of hospitalization associated with infection with SARS-CoV-2 Omicron relative to Delta.
25 Jan, 2022 | 09:40h | UTCCommentaries:
Danish report: lower risk of hospitalisation with Omicron – Copenhagen Post
Commentary on Twitter
New Danish population-based cohort study confirms lower (36%, 95%CI 44%-25%) risk of hospitalization with Omicron compared with Delta.
The risk also seems to be reduced irrespective of vaccination status.Pre-print can be found here: https://t.co/LfRrw1H3CY pic.twitter.com/Ql3zPyZyRE
— Anders Husby (@a_husby) January 20, 2022
ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question in children.
25 Jan, 2022 | 09:33h | UTCSee complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
We will be living with COVID for foreseeable future; but we can end acute phase of pandemic this year — WHO Director General.
25 Jan, 2022 | 09:34h | UTC
Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.
25 Jan, 2022 | 09:30h | UTCRelated Guideline: Media and Young Minds – American Academy of Pediatrics
Developing a how-to-guide for Health Technology Reassessment: “The HTR Playbook”.
25 Jan, 2022 | 09:26h | UTC
[Preprint] Omicron SARS-CoV-2 variant is associated with reduced risk of hospitalization and length of stay compared with Delta.
25 Jan, 2022 | 09:37h | UTC
Commentary on Twitter
In Portugal, Omicron hospitalizations were 75% reduced compared with Delta, risk adjusted. Vaccination reduced hospitalizations 84%, w/a booster 93%https://t.co/MvkfuF3mzx pic.twitter.com/zyk2INWNis
— Eric Topol (@EricTopol) January 23, 2022
Testicular seminoma and non-seminoma: ESMO-EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up.
25 Jan, 2022 | 09:28h | UTC
Diagnosis and Evaluation of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review.
25 Jan, 2022 | 09:25h | UTC
Review: Diagnosis and management of functional neurological disorder.
25 Jan, 2022 | 09:22h | UTCDiagnosis and management of functional neurological disorder – The BMJ
Management of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review.
25 Jan, 2022 | 09:24h | UTC
RCT: Single-dose 1000 mg ertapenem is non-inferior to single-dose 500 mg ceftriaxone for the treatment of gonorrhea.
25 Jan, 2022 | 09:20h | UTCEfficacy of ertapenem, gentamicin, fosfomycin, and ceftriaxone for the treatment of anogenital gonorrhoea (NABOGO): a randomised, non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
New from @TheLancetInfDis Efficacy of ertapenem, gentamicin, fosfomycin, and ceftriaxone for the treatment of anogenital gonorrhoea (NABOGO): a randomised, non-inferiority trial by @henryjdevries and colleagues https://t.co/K2fw5ORNlm pic.twitter.com/d8wz1Vc41Q
— The Lancet HIV (@TheLancetHIV) January 24, 2022
Podcast: Erectile dysfunction pearls.
25 Jan, 2022 | 09:16h | UTC#317 Erectile Dysfunction – The Curbsiders
Podcast: Inflammatory bowel disease in children.
25 Jan, 2022 | 09:18h | UTC#42: Inflammatory Bowel Disease – Go With Your Gut – The Cribsiders
RCT: Safety and efficacy of Daridorexant in patients with insomnia disorder.
25 Jan, 2022 | 09:15h | UTCSafety and efficacy of daridorexant in patients with insomnia disorder: results from two multicentre, randomised, double-blind, placebo-controlled, phase 3 trials – The Lancet Neurology (link to abstract – $ for full-text)
RCT: Fentanyl vs. placebo with ketamine and rocuronium for patients undergoing rapid sequence intubation in the emergency department.
25 Jan, 2022 | 09:14h | UTCFentanyl versus placebo with ketamine and rocuronium for patients undergoing rapid sequence intubation in the emergency department: the FAKT study – a randomized clinical trial – Academic Emergency Medicine (link to abstract – $ for full-text)
Global, regional, and national time trends in mortality for congenital heart disease, 1990–2019: An age-period-cohort analysis for the Global Burden of Disease 2019 study.
25 Jan, 2022 | 09:13h | UTC
Commentary on Twitter
A new study using data from the #GBD 2019 study estimated trends in congenital #heartdisease (CHD) mortality in 204 countries and territories over the past 30 years.
Read more here: https://t.co/6NtW0TYMAG pic.twitter.com/VLCU9OuOwx
— eClinicalMedicine – The Lancet Discovery Science (@eClinicalMed) January 14, 2022
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight.
25 Jan, 2022 | 09:09h | UTCAfter a flurry of firsts, xenotransplantation is suddenly back in the spotlight – STAT
Related: In 1st, US surgeons transplant pig heart into human patient.
Cohort study: In patients with a prosthetic joint, prophylactic antibiotics are probably not needed for invasive dental procedures.
25 Jan, 2022 | 09:11h | UTCCommentary: Prophylactic Antibiotics Not Needed Before Invasive Dental Procedures – HealthDay
Commentary on Twitter
Case-crossover study analyzing the incidence of invasive dental procedures (IDP) over the 15-months before 9,427 late prosthetic joint infection hospital admissions (LPJI) and found no evidence of a temporal association b/w IDP and LPJI. https://t.co/hcpwpN0B4H
— JAMA Network Open (@JAMANetworkOpen) January 19, 2022
Long-term results of RCT: GH replacement with once-weekly somapacitan is comparable to daily GH in children with growth hormone deficiency.
25 Jan, 2022 | 09:07h | UTC
RCT: A low FODMAP diet reduces symptoms in treated celiac patients with ongoing symptoms.
25 Jan, 2022 | 09:03h | UTC
Commentary on Twitter
A low FODMAP diet reduces symptoms in ‘𝘁𝗿𝗲𝗮𝘁𝗲𝗱’ #celiac patients with ongoing symptoms – a randomized controlled trial.
Brilliant RCT! Important word in the title is… ‘Treated’ (ie in histopathological remission).😉
🔓 https://t.co/R7oSnNhsWI pic.twitter.com/d0wbAa2nFg
— Nick Trott (@trott_nick) January 22, 2022
Massive open index of scholarly papers launches – “OpenAlex catalogues hundreds of millions of scientific documents and charts connections between them”.
25 Jan, 2022 | 09:04h | UTCMassive open index of scholarly papers launches – Nature
M-A: BRCA1 and BRCA2 pathogenic variants and prostate cancer risk.
25 Jan, 2022 | 09:01h | UTC
European CDC on Omicron: “among Omicron cases reported to TESSy, 1.14% were hospitalised, 0.16% required ICU admission/respiratory support, and 0.06% died”.
24 Jan, 2022 | 08:54h | UTC
Case-control study: 3 doses of mRNA vaccines were associated with reduced infections with SARS-CoV-2 Omicron and Delta variants compared to no vaccination or 2 doses.
24 Jan, 2022 | 08:56h | UTCCommentaries: New data show booster doses protect against Omicron – CIDRAP
Related CDC Studies:
Commentary on Twitter
Study suggests receipt of 3 doses of mRNA #COVID19 vaccine, vs 2 doses or being unvaccinated, was associated with protection against both the Omicron and Delta variants; higher odds ratios for Omicron suggest less protection for Omicron than for Delta. https://t.co/kOZh0fq5TL
— JAMA (@JAMA_current) January 21, 2022