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Daily Archives: July 28, 2022

RCT | Supplemental Vitamin D does not reduce incident fractures in midlife and older adults.

28 Jul, 2022 | 13:31h | UTC

Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Daily Vitamin D supplements don’t lower risk of bone fractures, study finds – STAT

Related:

Comparison of fracture risk using different supplemental doses of vitamin D, calcium or their combination: a network meta-analysis of randomised controlled trials – BMJ Open

Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis – JAMA

 

Commentary on Twitter

 


M-A | Prognosis and persistence of smell and taste dysfunction in patients with covid-19.

28 Jul, 2022 | 13:28h | UTC

Prognosis and persistence of smell and taste dysfunction in patients with covid-19: meta-analysis with parametric cure modelling of recovery curves – The BMJ

Editorial: Smell and taste dysfunction after covid-19 – The BMJ

Commentary: The burden of prolonged smell and taste loss in covid-19 – The BMJ

News Release: Millions of covid patients may have long term smell and taste problems – BMJ Newsroom

 


M-A | Nonoperative vs. operative management of uncomplicated acute appendicitis.

28 Jul, 2022 | 13:30h | UTC

Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis – JAMA Surgery (free for a limited period)

Related:

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

 

Commentary on Twitter

 


RCT | Effects of walking exercise at a pace with vs. without ischemic leg symptoms on functional performance measures in people with lower extremity peripheral artery disease.

28 Jul, 2022 | 13:27h | UTC

Effects of Walking Exercise at a Pace With Versus Without Ischemic Leg Symptoms on Functional Performance Measures in People With Lower Extremity Peripheral Artery Disease: The LITE Randomized Clinical Trial – Journal of the American Heart Association

News Release: ‘No pain, no gain’ approach improves walking ability with peripheral artery disease – American Heart Association

 


Perspective | Climbing melatonin use for insomnia raises safety concerns.

28 Jul, 2022 | 13:24h | UTC

Climbing Melatonin Use for Insomnia Raises Safety Concerns – JAMA (free for a limited period)

 


Guideline | Eyelid surgery for upper visual field improvement.

28 Jul, 2022 | 13:19h | UTC

American Society of Plastic Surgeons Evidence-Based Clinical Practice Guideline: Eyelid Surgery for Upper Visual Field Improvement – Plastic and Reconstructive Surgery (free for a limited period)

 


Cohort Study | Physical and mental activity, disease susceptibility, and risk of dementia.

28 Jul, 2022 | 13:22h | UTC

Physical and Mental Activity, Disease Susceptibility, and Risk of Dementia: A Prospective Cohort Study Based on UK Biobank – Neurology

News Release: Study: Chores, exercise, and social visits linked to lower risk of dementia – American Academy of Neurology

 


NICE Guideline Update | Melanoma: assessment and management.

28 Jul, 2022 | 13:21h | UTC

Melanoma: assessment and management – National Institute for Health and Care Excellence

 


Guideline | Management of diabetic macular edema.

28 Jul, 2022 | 13:18h | UTC

Management of Diabetic Macular Edema: Guidelines from the Emirates Society of Ophthalmology – Ophthalmology and Therapy

 


Consensus statement on the management of familial hypercholesterolemia.

28 Jul, 2022 | 13:16h | UTC

2022 Consensus statement on the management of familial hypercholesterolemia in Korea – The Korean Journal of Internal Medicine

 


Cohort Study | Androgen-deprivation therapy and risk of death from cardio-vascular disease in prostate cancer patients.

28 Jul, 2022 | 13:13h | UTC

Androgen-deprivation therapy and risk of death from cardio-vascular disease in prostate cancer patients: a nationwide lithuanian population-based cohort study – The Aging Male

News Release: Hormone therapy for prostate cancer increases the risk of dying from cardiovascular disease – Taylor & Francis

 


Cohort Study | Predictive utility of a validated polygenic risk score for long-term risk of coronary heart disease in young and middle-aged adults.

28 Jul, 2022 | 13:15h | UTC

Predictive Utility of a Validated Polygenic Risk Score for Long-Term Risk of Coronary Heart Disease in Young and Middle-Aged Adults – Circulation (free for a limited period)

News Release: Old-School Health Assessment Beats Genetic Test for Predicting Heart Disease – Nuke University

 


Cohort Study | Association of ultraprocessed food consumption with risk of dementia.

28 Jul, 2022 | 13:10h | UTC

Association of Ultraprocessed Food Consumption With Risk of Dementia: A Prospective Cohort – Neurology (link to abstract – $ for full-text)

Commentary: Dementia Risk Climbs With Intake of Ultra-Processed Foods — Swapping out ultra-processed for unprocessed or minimally processed foods can lower risk sharply – MedPage Today (link to abstract – $ for full-text)

 


RCT | Efficacy and safety of topical hypericin photodynamic therapy for early-stage Cutaneous T-Cell Lymphoma (Mycosis Fungoides).

28 Jul, 2022 | 13:09h | UTC

Efficacy and Safety of Topical Hypericin Photodynamic Therapy for Early-Stage Cutaneous T-Cell Lymphoma (Mycosis Fungoides): The FLASH Phase 3 Randomized Clinical Trial – JAMA Dermatology (free for a limited period)

 

Commentary on Twitter

 


Comparison of 6 mortality risk scores for prediction of 1-year mortality risk in older adults with multimorbidity.

28 Jul, 2022 | 13:07h | UTC

Comparison of 6 Mortality Risk Scores for Prediction of 1-Year Mortality Risk in Older Adults With Multimorbidity – JAMA Network Open

 


M-A | Breast cancer recurrence after immediate and delayed postmastectomy breast reconstruction.

28 Jul, 2022 | 13:05h | UTC

Breast cancer recurrence after immediate and delayed postmastectomy breast reconstruction—A systematic review and meta-analysis – Cancer

 


RCT | Trial of Anti-BDCA2 antibody Litifilimab for cutaneous Lupus Erythematosus.

28 Jul, 2022 | 13:06h | UTC

Trial of Anti-BDCA2 Antibody Litifilimab for Cutaneous Lupus Erythematosus – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: BDCA2-Targeting Antibody May Be Effective for Cutaneous Lupus — In small randomized trial, litifilimab shows superiority over placebo for skin disease activity – MedPage Today (free registration required)

 

Commentary on Twitter

 


M-A | Negative-pressure wound therapy for prevention of sternal wound infection after adult cardiac surgery.

28 Jul, 2022 | 13:03h | UTC

Negative-Pressure Wound Therapy for Prevention of Sternal Wound Infection after Adult Cardiac Surgery: Systematic Review and Meta-Analysis – Journal of Clinical Medicine

 


M-A | The efficacy of topical sucralfate in improving pain and wound healing after hemorrhoidectomy procedure.

28 Jul, 2022 | 13:02h | UTC

The efficacy of topical sucralfate in improving pain and wound healing after haemorrhoidectomy procedure: A systematic review, meta-analysis, and meta-regression of randomised clinical trials – International Wound Journal

 


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