Systematic Reviews & Meta-analysis
Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations
14 Jan, 2021 | 01:36h | UTCMeta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations – Surgery (link to abstract – $ for full-text)
Systematic review: Immunotherapy vs. chemotherapy for people with advanced non-small cell lung cancer who have not been previously treated
14 Jan, 2021 | 01:30h | UTC
#Immunotherapy vs #chemotherapy for people with advanced non‐small cell #lungcancer who have not been not previously been treated https://t.co/RJlDp1SHTc New @CochraneLibrary systematic review includes 7 studies with 5893 participants.
— The Cochrane Library (@CochraneLibrary) December 21, 2020
Systematic review: Acute treatments for episodic migraine
13 Jan, 2021 | 01:56h | UTCAcute Treatments for Episodic Migraine – Agency for Healthcare Research and Quality
Full text: Acute Treatments for Episodic Migraine
Evidence summary: Acute Treatments for Episodic Migraine
Systematic review: Treatments for acute pain
13 Jan, 2021 | 01:55h | UTCTreatments for Acute Pain: A Systematic Review – Agency for Healthcare Research and Quality
Full text: Treatments for Acute Pain
Evidence summary: Treatments for Acute Pain
Systematic review: There is no evidence that Souvenaid is useful for preventing dementia or provide benefit for patients with Alzheimer’s disease
13 Jan, 2021 | 01:47h | UTCSouvenaid for Alzheimer’s disease – Cochrane Library
Systematic review: Treatment with antenatal corticosteroids in women at risk of preterm birth reduces the risk of perinatal death, neonatal death, respiratory distress syndrome, and the risk of intraventricular hemorrhage
13 Jan, 2021 | 01:46h | UTC
Systematic review: Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy
13 Jan, 2021 | 01:37h | UTC
Systematic Review: “For the general population of persons with elevated blood pressure, the benefits of trying to achieve a lower blood pressure target rather than a standard target (140/90 mm Hg or less) do not outweigh the harms associated with that intervention.”
12 Jan, 2021 | 01:30h | UTCBlood pressure targets in adults with hypertension – Cochrane Library
Summary: The use of lower blood pressure targets for people with hypertension – Cochrane Library
Related systematic review: Blood pressure targets in people with cardiovascular disease – Cochrane Library
Commentary on Twitter
The use of lower #bloodpressure targets for people with #hypertension https://t.co/W1bF8W7CDD Updated @CochraneHTN systematic review includes 11 randomised controlled trials involving 38,688 adult participants.
— Cochrane (@cochranecollab) December 30, 2020
Systematic review: Prevention of childhood unintentional injuries in low- and middle-income countries
12 Jan, 2021 | 01:23h | UTCRelated: World report on child injury prevention – World Health Organization
[Abstract Only] Meta-Analysis: Not enough evidence to recommend the use of a prosthetic Mesh for prevention of parastomal hernia
12 Jan, 2021 | 01:18h | UTCMeta-Analysis and Systematic Review of the Use of a Prosthetic Mesh for Prevention of Parastomal Hernia – Annals of Surgery (link to abstract – $ for full-text)
Meta-analysis: Total neoadjuvant therapy vs. standard therapy in locally advanced rectal cancer
12 Jan, 2021 | 01:10h | UTCCommentaries: Personalizing Treatment for Rectal Cancer: Total Neoadjuvant Therapy Is Leading the Way AND Total Neoadjuvant Therapy Improves Rectal Cancer Pathologic Response – Physician’s Weekly
Related meta-analysis (just published): Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials – Cancers
Commentary on Twitter
Systematic review & meta-analysis finds total neoadjuvant therapy for locally adv. rectal cancer is associated with a doubling of pathologic complete response vs standard chemoradiation plus by adjuvant chemo. @anup_kasi @KUMedCenter @geriradonc @agrothey https://t.co/oRccCh5bEb
— JAMA Network Open (@JAMANetworkOpen) December 16, 2020
Systematic review: Effectiveness of hospital clowns for symptom management in pediatrics
10 Jan, 2021 | 20:24h | UTCCommentaries: Clowns may help children cope with the pain and anxiety of hospital treatment – The BMJ AND Clowns Make Hospitals Less Scary For Young Patients – Forbes AND Laughter As Medicine: Clowns Help Hospitalized Kids Cope – U.S News
Commentary on Twitter
As a gift ? to children everywhere, a @bmj_latest study shows that sending in the clowns – in pediatric hospital settings – may reduce children's stress, fatigue, #pain, and distress during a range of medical procedures"
By @lopesjr_phd, @Naramata4 et al#bioethics #ChronicPain pic.twitter.com/hmnXRv3J8Q— Sandra Woods, CIPP/C ??? (@SandraWoodsMtl) December 25, 2020
Meta-analysis: Effectiveness of bundle interventions on ICU delirium
10 Jan, 2021 | 20:16h | UTCEffectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine
Commentary: ICU bundles do not appear to improve delirium but may help other outcomes – ACP Hospitalist
Commentary on Twitter
Meta-Analysis incl 11 studies and 26,384 patients for bundle-interventions of delirium treatment showed no effects on delirum duration ( –1.42 d; 95% CI –3.06 to 0.22) or prevalence (risk ratio = 0.92; 95% CI, 0.68–1.24)https://t.co/PzZBGttOL8
— Peter Nydahl (@NydahlPeter) December 18, 2020
Effects of low sodium diet vs. high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride
10 Jan, 2021 | 20:12h | UTC
Systematic review: Infection and mortality of healthcare workers worldwide from COVID-19
17 Dec, 2020 | 08:40h | UTC
Commentary on Twitter
Just In from @GlobalHealthBMJ
•152,888 healthcare workers had #COVID19 by May 2020 already
•Infections in women (71.6%) & nurses(38.6%)
•Deaths in men (70.8%) & doctors(51.4%)
•Europe massively failed in infection control
• >70 years high deathshttps://t.co/wGlPwzzICe pic.twitter.com/Hj64nw9Nx6— Soumyadeep Bhaumik | সৌম্যদীপ ভৌমিক (@DrSoumyadeepB) December 5, 2020
Meta-analysis: Induction of labor at 41 weeks improves perinatal outcomes compared with expectant management until 42 weeks, without increasing the cesarean delivery rate
15 Dec, 2020 | 01:21h | UTC
Meta-analysis: Efficacy and harms of remdesivir for the treatment of COVID-19. “Until stronger evidence emerges, we cannot conclude that remdesivir is efficacious for treating COVID-19”.
13 Dec, 2020 | 23:27h | UTC
A systematic review of corticosteroid treatment for noncritically ill patients with COVID-19 – corticosteroid treatment is not recommended for patients with mild or moderate COVID-19
13 Dec, 2020 | 23:26h | UTC
Systematic review: Tourniquet use for knee replacement surgery is probably associated with an increased risk of serious adverse events
13 Dec, 2020 | 23:17h | UTCTourniquet use for knee replacement surgery – Cochrane Library
Commentary: Featured Review: Tourniquet in knee replacement surgery
Systematic review: Among patients with advanced chronic kidney disease and uremic pruritus, gabapentinoids are the most studied treatments and show the greatest reduction in itch scores
13 Dec, 2020 | 23:16h | UTCInterventions for itch in people with advanced chronic kidney disease – Cochrane Library
Commentary: What is the best treatment for itch in people with chronic kidney disease? – Cochrane Library
Systematic Review: Financial conflicts of interest are associated with favorable recommendations of drugs and devices in clinical guidelines, advisory committee reports, opinion pieces, and narrative reviews
11 Dec, 2020 | 09:18h | UTC
Meta-analysis: Respiratory function post-infection by COVID-19. Altered diffusion capacity, restrictive pattern, and obstructive pattern were found in 39%, 15% and 7% of patients, respectively
7 Dec, 2020 | 01:04h | UTC
Commentary on Twitter
Check out our recent systematic review in post-COVID-19 patients. Altered diffusion capacity, restrictive pattern and obstructive pattern were found in 39%, 15% and 7% of patients, respectively. @VilaroJordi @lvasconcello @RestoyAlsina @BufadorBufador https://t.co/PDHcUOCEbw
— Rodrigo Torres Castro (@klgorodtorres) November 25, 2020
Meta-analysis reinforces the safety of betablockers in patients with COPD and cardiovascular disease
6 Dec, 2020 | 23:30h | UTCCommentary: Beta-Blockers in Patients With COPD and CVD – American College of Cardiology
Meta-analysis: High-quality evidence supports fecal microbiota transplantation is effective for recurrent Clostridioides difficile infection
6 Dec, 2020 | 23:35h | UTC
Meta-analysis: Epidural corticosteroid injections for sciatica are effective, although the effects are small and short-term
4 Dec, 2020 | 08:26h | UTC