Systematic Reviews & Meta-analysis
Systematic review on prophylaxis for COVID-19: Hydroxychloroquine does not work, little evidence regarding other drugs
20 Jan, 2021 | 01:38h | UTCProphylaxis for COVID-19: a systematic review – Clinical Microbiology and Infection
Meta-analysis: Inconclusive evidence regarding a benefit of systematic early mobilization in mechanically ventilated adult ICU patients
20 Jan, 2021 | 01:24h | UTC
Meta-analysis: Comparison of the loop technique with incision and drainage for skin and soft tissue abscesses
20 Jan, 2021 | 01:22h | UTC
Commentary on Twitter
Loop drainage technique (LDT) vs conventional I&D (CID) for cutaneous abscess
8 studies (n=910)
CID failed in 69/487 pts (14%)
LDT failed in 35/423 pts (8%)
OR 2.02 (95% CI 1.29 to 3.18) https://t.co/JVRZWFfyUe@MGottliebMD @GillianMD1 @AcademicEmerMed @SAEMonline #AEM pic.twitter.com/HJfnou4NYc— Gary D Peksa ? (@garyDpeksa) October 15, 2020
Epidural corticosteroid injections for sciatica: An abridged Cochrane systematic review and meta-analysis
20 Jan, 2021 | 01:16h | UTCSource: EvidenceAlerts
Systematic review: Insufficient evidence of benefit from immediate‐release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults
20 Jan, 2021 | 01:11h | UTCIR methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults – Cochrane Library
Original study: Immediate‐release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults – Cochrane Library
Systematic review: Intra-articular ketamine for postoperative analgesia
20 Jan, 2021 | 01:13h | UTC
Commentary on Twitter
What is the impact of intra-articular ketamine for postoperative analgesia?https://t.co/61ECP4EOZ2#physiatry #rehab #painmanagement #ketamine pic.twitter.com/wEQhUvyd8E
— AJPM&R (@AJPMRjournal) November 16, 2020
Systematic review: Does adding iron to wheat flour reduce anemia and increase iron levels in the general population?
20 Jan, 2021 | 01:10h | UTCOriginal study: Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations – Cochrane Library
Meta-analysis: Bisphosphonates or RANK‐ligand‐inhibitors for men with prostate cancer and bone metastases
20 Jan, 2021 | 01:09h | UTC
Meta-analysis: Corticosteroid use in COVID-19 patients
19 Jan, 2021 | 01:56h | UTCRelated meta-analysis: Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials – Journal of Cardiothoracic and Vascular Anesthesia
Meta-analysis: saliva and nasopharyngeal swab nucleic acid amplification have similar diagnostic accuracy for the detection of SARS-CoV-2
19 Jan, 2021 | 01:46h | UTC
Meta-Analysis: After transcatheter aortic valve implantation, Aspirin alone is a better choice than dual antiplatelet therapy
19 Jan, 2021 | 01:34h | UTCMeta-Analysis Comparing the Safety and Efficacy of Single vs. Dual Antiplatelet Therapy in Post Transcatheter Aortic Valve Implantation Patients. – American Journal of Cardiology (link to abstract – $ for full-text)
Meta-analysis: The effect of low-fat and low-carbohydrate diets on weight loss and lipid levels
19 Jan, 2021 | 01:18h | UTC
Systematic review: Time-restricted eating’s effects on human health
19 Jan, 2021 | 01:16h | UTC
Systematic review: Little evidence of benefit from vitamin D supplementation on linear growth and other health outcomes among children under five years of age
19 Jan, 2021 | 01:11h | UTC
Systematic review: The association of Alvimopan treatment with postoperative outcomes after abdominal surgery
19 Jan, 2021 | 01:05h | UTCThe association of alvimopan treatment with postoperative outcomes after abdominal surgery: A systematic review across different surgical procedures and contexts of perioperative care – Surgery (link to abstract – $ for full-text)
Meta-analysis: Prophylactic macrolides beneficial for patients with COPD with frequent exacerbations
17 Jan, 2021 | 22:09h | UTCSummary: Prophylactic antibiotics for people with COPD – Cochrane Library
Meta-analysis of observational studies: Proton pump inhibitors linked to increased risk for recurrent Clostridioides difficile infection
17 Jan, 2021 | 22:00h | UTC
Systematic review: Insufficient evidence to recommend Trypanocidal drugs for late-stage, symptomatic Chagas disease
17 Jan, 2021 | 21:44h | UTCSummary: Trypanocidal drugs for late-stage, symptomatic Chagas disease – Cochrane Library
Meta-analysis: Safety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation
17 Jan, 2021 | 21:42h | UTCSafety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation: a systematic review and meta-analysis of randomized trials – CHEST (link to abstract – $ for full-text)
Meta-analysis: Effect of ultra-short-acting β-blockers on mortality in patients with persistent tachycardia despite initial resuscitation
17 Jan, 2021 | 21:41h | UTCEffect of ultra-short-acting β-blockers on mortality in patients with persistent tachycardia despite initial resuscitation: a systematic review and meta-analysis of randomized controlled trials – CHEST (link to abstract – $ for full-text)
Meta-analysis of randomized trials: patients adhering to a low carbohydrate diet for six months may experience remission of diabetes without adverse consequences
15 Jan, 2021 | 08:43h | UTCCommentary: Short term low carbohydrate diet linked to remission of type 2 diabetes – The BMJ
Short term low carbohydrate diet linked to remission of type 2 diabetes in new #BMJResearch. But further trials are needed to determine longer term effects, say researchers @methodsnerd et al.
Includes a #VisualAbstract by @will_s_t #BMJInfographichttps://t.co/qihKAib11U pic.twitter.com/3rPH0ZrSGL— The BMJ (@bmj_latest) January 14, 2021
Meta-analysis of randomized trials: SGLT-2 inhibitors and GLP-1 receptor agonists reduce cardiovascular and renal outcomes in type 2 diabetes
15 Jan, 2021 | 08:41h | UTCCalculator based on the results: interactive decision support tool for outcomes
Systematic review: Prostatic arterial embolization for men with symptomatic benign prostatic hyperplasia provides similar short term (up to 12 months) improvement in urologic symptom scores and quality of life, but with an increase in re-treatment rates
15 Jan, 2021 | 08:11h | UTC
Systematic review: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer
15 Jan, 2021 | 08:10h | UTC
Systematic review: Oral hygiene care with chlorhexidine mouthwash or gel in critically ill patients probably reduces the incidence of developing ventilator-associated pneumonia
15 Jan, 2021 | 08:09h | UTC