Systematic Reviews & Meta-analysis
M-A: Interventions to minimize blood loss in very preterm infants
10 Feb, 2021 | 01:19h | UTC
Defining the role of asymptomatic and pre-symptomatic SARS-CoV-2 transmission – a living systematic review
10 Feb, 2021 | 01:45h | UTCRelated: Infectivity of asymptomatic versus symptomatic COVID-19 – The Lancet AND Asymptomatic transmission of covid-19 – The BMJ
Canadians Win Again – Syncope Score Systematic Review
9 Feb, 2021 | 01:03h | UTCCanadians Win Again – Syncope Score Systematic Review – Journal Feed
See calculator: Canadian Syncope Risk Score – MdCalc
M-A: Effects of whole grain intake, compared with refined grain, on appetite and energy intake
9 Feb, 2021 | 00:50h | UTC
Commentary on Twitter
Effects of Whole Grain Intake, Compared with Refined Grain, on Appetite and Energy Intake: A Systematic Review and Meta-Analysis
"Whole grains modestly but significantly reduced
hunger…"https://t.co/wS1Vql4KHi@nutritionorg @jnutritionorg pic.twitter.com/5UWa28wkPW— Lukas Schwingshackl (@LSchwingshackl) February 8, 2021
SR/MA: Up to a third of patients may discontinue thyroid hormone replacement and remain euthyroid
7 Feb, 2021 | 21:02h | UTCClinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis – Thyroid (link to abstract – $ for full-text)
Commentary: A Third Discontinuing Levothyroxine Have Normal Thyroid Levels – Medscape (free registration required)
Commentaries on Twitter
Hard to believe that simply treating hypothyroidism may fit into “Things We Do For No Reason.”
But >1/3 of people on thyroid replacement stay euthyroid after stopping meds.
See article for results, predictors of euthyroidism, & de-escalation strategies.https://t.co/i1f04FnbPk pic.twitter.com/fGLAbjNo5B
— David A. Cohen (@DavidACohen_MD) January 21, 2021
(thread – click for more)
#endocation #endotwitter #endotips #endorules
Hypothyroidism🧠: Third of Patients Treated for
Hypothyroidism May Not Require Thyroid Hormones❗️https://t.co/iAZcwFB5Ul✅Hypothyroidism: 5% of population, age dependent
✅NHANES: 6.4% reported use of levothyroxine (LT4)1/
— Fady Hannah-Shmouni, MD FRCPC (@DrShmouni) January 14, 2021
SR/MA: ICU mortality from COVID-19 continued to fall in 2020, but improvement is slowing
7 Feb, 2021 | 21:18h | UTCNews release: ICU mortality from COVID-19 continued to fall in 2020, but improvement is slowing – University of Bristol
Original article: Mortality in patients admitted to intensive care with COVID‐19: an updated systematic review and meta‐analysis of observational studies – Anaesthesia
Commentary on Twitter
🔐Has mortality from COVID‐19 in patients admitted to the ICU changed again?@drrichstrong, @adk300, @emirakur and @doctimcook update their previous analysis and find that any fall in mortality rate between June and September appears to have plateaued.
🔗https://t.co/zp8ygzp78A pic.twitter.com/g21p3rcjY6
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) February 2, 2021
Systematic review: Telerehabilitation for chronic respiratory disease
4 Feb, 2021 | 01:08h | UTCTelerehabilitation for chronic respiratory disease – Cochrane Library
[Preprint] Meta-analysis: More than 50 Long-term effects of COVID-19
4 Feb, 2021 | 01:26h | UTCMore than 50 Long-term effects of COVID-19: a systematic review and meta-analysis – medRxiv
Commentary: 80% of COVID-19 Patients May Have Lingering Symptoms, Signs — More than 50 effects persisted after acute infection, meta-analysis shows – MedPage Today (free registration required)
Systematic review: Intermittent fasting for the prevention of cardiovascular disease
4 Feb, 2021 | 01:01h | UTCIntermittent fasting for the prevention of cardiovascular disease – Cochrane Library
Living systematic review on Cannabis and other plant-based treatments for chronic pain
2 Feb, 2021 | 01:01h | UTC
Meta-analysis: Minimally invasive surgery versus transcatheter aortic valve replacement
27 Jan, 2021 | 01:00h | UTCCommentary: TAVI vs Minimally Invasive AVR Yields Surprising Findings: Meta-analysis – TCTMD
Commentary on Twitter
Comprehensive systematic review and meta-analysis of miniAVR vs #TAVR. Important in the context of 'lifetime management of valves'. Thank you for the opportunity. @Shoukmed @ahmedsayed8991 @BrighamSurgery @BrighamThoracic CC:@TSRA_official @STS_CTsurgery @AATSED @ThoracicsCanada https://t.co/T1XDrebl8U pic.twitter.com/5E5eOLherA
— Sameer Hirji (@Hirji1987) January 21, 2021
Meta-analysis of observational studies: Fried-food consumption linked to increased risk of cardiovascular disease and all-cause mortality
27 Jan, 2021 | 00:55h | UTCCommentaries: Fried food intake linked to heightened serious heart disease and stroke risk – The BMJ AND Expert reaction to study looking at fried food and heart disease and stroke risk – Science Media Centre
Systematic review: Payment methods for healthcare providers working in outpatient healthcare settings
27 Jan, 2021 | 00:56h | UTCSummary: Payment methods for healthcare providers in outpatient healthcare settings – Cochrane Library
Commentary on Twitter
Payment methods for #healthcare providers in #outpatient healthcare settings https://t.co/wY6LKEmhbZ New @CochraneEPOC systematic review w evidence from 27 studies suggests that different payment methods can affect healthcare provider behaviour in both positive and negative ways.
— Cochrane (@cochranecollab) January 21, 2021
Systematic review: Cardiopulmonary resuscitation in the prone position in the operating room or in the intensive care unit
27 Jan, 2021 | 01:14h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/IARS_Journals/status/1350827861016535043
Meta-analysis: Effect of micronutrient supplements on influenza and other respiratory tract infections among adults
25 Jan, 2021 | 01:17h | UTC
Commentary on Twitter (thread – click for more)
Our new article in @GlobalHealthBMJ suggests that zinc supplementation could almost halve the duration of symptoms of acute respiratory infection in adults. We also found small effects of vitamins C and D supplementation to prevent ARIs. [Thread]https://t.co/aJ4VfYFiBG
— Ibraheem Abioye (@DrAbioye) January 20, 2021
Meta-analysis: Does near-infrared fluorescent cholangiography with indocyanine green reduce bile duct injuries and conversions to open surgery during laparoscopic or robotic cholecystectomy?
25 Jan, 2021 | 01:06h | UTCDoes near-infrared fluorescent cholangiography with indocyanine green reduce bile duct injuries and conversions to open surgery during laparoscopic or robotic cholecystectomy? — A meta-analysis – Surgery (link to abstract – $ for full-text)
Systematic review: Indomethacin for symptomatic patent ductus arteriosus in preterm infants
25 Jan, 2021 | 01:02h | UTCIndomethacin for symptomatic patent ductus arteriosus in preterm infants – Cochrane Library
Meta-analysis: Multiple intra-articular corticosteroid injections are no better than placebo for osteoarthritis pain
25 Jan, 2021 | 00:56h | UTC
Meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis
22 Jan, 2021 | 08:27h | UTCCommentary: Do antidepressants help back pain and osteoarthritis? – University of Sidney AND Antidepressants largely ineffective for back pain and osteoarthritis – The BMJ
Editorial: Antidepressants for musculoskeletal pain – The BMJ
Commentary on Twitter
Antidepressant drugs are largely ineffective for back and osteoarthritis pain, despite being widely used for these conditions, suggests a review of the evidence published by @bmj_latest https://t.co/pBmzSx0NLk @giovanni_ef
— BMJ Group (@bmj_company) January 21, 2021
Meta-analysis: Colchicine reduces new cardiovascular events in patients with coronary artery disease
22 Jan, 2021 | 08:23h | UTCMeta-analysis Evaluating the Utility of Colchicine in Secondary Prevention of Coronary Artery Disease – The American Journal of Cardiology (link to abstract – $ for full-text)
Related randomized trials: Colchicine in patients with chronic coronary disease (study and commentaries) AND Low-Dose Colchicine Improves Outcomes after Myocardial Infarction (study and commentaries) AND Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT) (study and commentary)
Commentary on Twitter
Meta-analysis Evaluating the Utility of Colchicine in Secondary Prevention of Coronary Artery Disease https://t.co/EbMATgpXn4
🔽Major adverse CV events 35%
🔽Risk of MI 27%
🔽Coronary revasc 39%
🔽Stroke 53% (0.47, CI 0.28-0.81)
🔴No impact on CV mortality@mencardio #colchicine— Lempira Guevara Matheus (@Lguevaramath) October 31, 2020
Meta-analysis: Clinical presentation, investigation findings, and treatment outcomes of spontaneous intracranial hypotension syndrome
22 Jan, 2021 | 08:12h | UTC
Commentary on Twitter
This meta-analysis offers a comprehensive and objective summary of the evidence on SIH. Spontaneous intracranial hypotension should not be excluded on the basis of a non-orthostatic headache, normal neuroimaging or normal lumbar puncture opening pressure https://t.co/BcVk2ftcs3
— JAMA Neurology (@JAMANeuro) January 4, 2021
Pharmacological and non-pharmacological therapeutic strategies in difficult-to-treat rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of difficult-to-treat rheumatoid arthritis
22 Jan, 2021 | 08:08h | UTC
Meta-analysis: Prevalence of postural hypotension in primary, community and institutional care
22 Jan, 2021 | 08:09h | UTC
Meta-analysis: Outcomes of endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid
22 Jan, 2021 | 08:04h | UTC
Commentary on Twitter
Outcomes of non-endotracheal suctioning (non-ETS) versus ETS in non-vigorous meconium-stained neonates = no difference
Published in @ADC_FN https://t.co/raRs4uj73o pic.twitter.com/AAGQiKyc5a
— Evidence-Based Neo (@EBNEO) June 25, 2020
Meta-analysis of randomized trials: Closed incision negative pressure wound therapy decreases surgical site infections compared to standard dressings after revision total joint arthroplasty, but not primary total joint arthroplasty
22 Jan, 2021 | 08:02h | UTCClosed Incision Negative Pressure Wound Therapy for Elective Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Journal of Arthroplasty (link to abstract – $ for full-text)